Aceclofenac tablets coated.pl.ob. 100 mg 20 pcs. (Aceclofenac)
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$20.40
Regular Price
$24.00
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SKU
newyork827306
Pharmacological action of
Aceclofenac is a non-steroidal anti-inflammatory drug derived from phenylacetic acid. Aceclofenac has an analgesic, anti-inflammatory, antipyretic effect, which are associated with the inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is time which are associated with inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is time which are associated with inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is timeThe dose is reached 2 to 4 hours longer than in plasma. The distribution volume of aceclofenac is 25 liters. Aceclofenac binds to plasma proteins (albumin) by 99%. Aceclofenac circulates mainly unchanged, its main metabolite is 4'-hydroxyaceclofenac. the half-life is 4 hours. Aceclofenac is excreted by the kidneys, more than 60% in the form of hydroxy derivatives. Buy Aceclofenac tablets coated.pl.ob. 100 mg 20 pcs. (Aceclofenac) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Aceclofenac is a non-steroidal anti-inflammatory drug derived from phenylacetic acid. Aceclofenac has an analgesic, anti-inflammatory, antipyretic effect, which are associated with the inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is time which are associated with inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is time which are associated with inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is timeThe dose is reached 2 to 4 hours longer than in plasma. The distribution volume of aceclofenac is 25 liters. Aceclofenac binds to plasma proteins (albumin) by 99%. Aceclofenac circulates mainly unchanged, its main metabolite is 4'-hydroxyaceclofenac. the half-life is 4 hours. Aceclofenac is excreted by the kidneys, more than 60% in the form of hydroxy derivatives. Buy Aceclofenac tablets coated.pl.ob. 100 mg 20 pcs. (Aceclofenac) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Pharmacological action of
Aceclofenac is a non-steroidal anti-inflammatory drug derived from phenylacetic acid. Aceclofenac has an analgesic, anti-inflammatory, antipyretic effect, which are associated with the inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is time which are associated with inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is time which are associated with inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is timeThe dose is reached 2 to 4 hours longer than in plasma. The distribution volume of aceclofenac is 25 liters. Aceclofenac binds to plasma proteins (albumin) by 99%. Aceclofenac circulates mainly unchanged, its main metabolite is 4'-hydroxyaceclofenac. the half-life is 4 hours. Aceclofenac is excreted by the kidneys, more than 60% in the form of hydroxy derivatives.
Indications
The drug is prescribed: as a part of the complex treatment of inflammatory diseases of the musculoskeletal system (osteoarthritis, rheumatoid, psoriatic and juvenile arthritis, gifts, ankylosing spondylitis or spondylitis)
for the relief of pain syndrome toothache, humeroscapular periarthritis.
Aceclofenac is not able to completely cure these diseases, but it quickly reduces inflammation and pain.
Contraindications
The medicine is contraindicated: for allergies to the active substance
to patients with ulcers and erosion in the digestive tract, during exacerbation of
in Crohn’s disease and ulcerative colitis
if there is a suspicion of bleeding from the gastrointestinal tract
in severe liver diseases and liver failure
in pregnant women
in patients with impaired hematopoiesis or blood clotting
during hypercalcea , progressive kidney disease
for children under 18
during the recovery period after coronary artery bypass grafting
with the “aspirin triad”
to individuals suffering from severe heart failure.
Caution should be observed: for kidney disease, of the gastrointestinal tract and liver of moderate and mild severity
if the patient has the helicobacter bacterium in the gastrointestinal tract
for bronchial asthma
for people with low blood pressure
after extensive surgery if the circulating blood volume
is reduced in elderly patients
cerebrovascular disease
in diabetes mellitus
after prolonged treatment of NSAIDs
for alcoholics and smokers
in severe somatic diseases
in patients with hemostatic defects
with stemnoy lupus erythematosus
combined with anticoagulants, serotonin reuptake inhibitors, antiplatelet.
Ointment or cream should not be applied to damaged skin.
Use during pregnancy and lactation
An absolute contraindication to the use of the product is the 3rd trimester of pregnancy.
Special care must be taken in the 1st and 2nd trimesters and during breastfeeding. The medicine can be prescribed by a doctor in case of urgent need.
Special instructions
It is recommended to use minimally effective and active dosages as a precaution during treatment with the drug. Periodic monitoring of the liver and kidneys, a picture of peripheral blood, feces (lack of blood), and the work of the cardiovascular system are also shown.
During treatment, you must not drive or perform potentially hazardous activities.
The risk of allergies or skin reactions is higher in the first months of taking the medicine. If there are injuries of the oral mucosa, skin rashes, other signs of allergy, then therapy should be interrupted.
The process of inhibition of platelets during treatment with the drug is reversible, the composition of the blood normalizes some time after drug withdrawal.
Composition
Active ingredients:
Aceclofenac - 100 mg
Excipients:
Core composition:
Calcium stearate - 3 mg
talc - 9 mg
Silicon colloidal dioxide (aerosil) - 1.5 mg
Microcrystalline cellulose - 85 mg
Croscarmellose sodium (primrose) - 10.5 mg
Lactose monohydrate (91 mg) (
Core mass - 300 mg
Shell composition:
Hypromellose (hydroxypropyl methylcellulose) - 6.4 mg
Macrogol - 4000 (polyethylene oxide-4000) - 2.5 mg
Titanium dioxide (titanium dioxide) - 1.1 mg
Tablet weight - 310 mg
Dosage and Administration
Tablets are prescribed by mouth. Depending on the disease and age of the patient, 100 to 200 mg of the drug per day is prescribed. 100 mg at a time, whole, without separation and without chewing, with a large amount of liquid.
Outwardly. The substance in the composition of the ointment or cream with a thin layer is carefully applied to the area of ​​inflammation 3 times a day. After using the drug, it is recommended to wash your hands thoroughly with soap, to prevent contact with eyes.
Side effects of
During Aceclofenac treatment, dizziness, nausea, abnormalities in the gastrointestinal tract, abdominal pain, indigestion, diarrhea
increase in liver enzyme activity, allergic reactions in the form of skin rashes and itching are often observed.
Less commonly developed: anemia, anaphylactic reactions, decreased visual acuity
increased blood pressure, heart failure, dyspnea
increased concentration of creatinine and urea in the blood
constipation, oral ulcers, increased gas formation, gastritis, gastric vomiting, hematitis, vomiting,
ulcer
dermatitis, itching, Quincke's edema, urticaria.
Very rarely occur: muscle cramps, weakness and a feeling of fatigue, weight gain, hyperkalemia, eczema
renal failure, nephrotic syndrome, purpura
nephritis, Stevens-Johnson syndrome, chicken pox soft tissue infections, toxic epidermal necrolysis of
granulocytopenia, impaired hematopoiesis, thrombocytopenia, hemolytic anemia
depression, vivid dreams and nightmares, nightmares, nightmares , vasculitis
tremor, taste perversion, drowsiness, paresthesia, tinnitus
perforation of the intestines, pancreatitis, ulcerative colitis, vomiting with blood
hyperemia of the skin, hot flashes, tachycardia
bronchospasm, stomatitis, hepatitis.
Drug Interactions
Anticoagulants when combined with tablets increase the risk of bleeding. During treatment, it is recommended to periodically monitor blood coagulation.
Aceclofenac tablets increase the plasma concentration of digoxin, phenytoin, lithium-based drugs.
The substance when combined with antihypertensive drugs and diuretics reduces the effectiveness of the latter.
The combination of the drug with potassium-sparing diuretics increases the likelihood of hyperkalemia.
With caution, the drug should be combined with NSAIDs and glucocorticosteroids, the drug increases the toxicity of methotrexate and cyclosporine.
Aspirin reduces the plasma concentration of aceclofenac.
The combination of drugs with hypoglycemic drugs requires constant monitoring of blood glucose levels.
Overdose
There have been no reported cases of drug overdose in humans.
Overdose symptoms are: headaches, cramps, vomiting, abdominal pain, nausea, dizziness. Enterosorbents are used as therapy, they wash the stomach and produce symptomatic treatment. The drug does not have a specific antidote, hemodialysis and forced diuresis are ineffective.
Storage conditions
Tablets are stored in a cool, dark place, away from children.
Expiration
3 years.
Deystvuyuschee substances
Aceclofenac
Conditions of supply of pharmacies
prescription
Form of Treatment
tablets
Appointment
Adult prescription, For athletes
Possible Product Names
Aceclofenac Tablets. 100 mg 20 pcs.
Aceclofenac tablets coated.pl.ob. 100 mg 20 pcs. (Aceclofenac) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Aceclofenac tablets coated.pl.ob. 100 mg 20 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
Aceclofenac is a non-steroidal anti-inflammatory drug derived from phenylacetic acid. Aceclofenac has an analgesic, anti-inflammatory, antipyretic effect, which are associated with the inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is time which are associated with inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is time which are associated with inhibition of cyclooxygenase 1 and 2, which regulate the production of prostaglandins. When taken orally, aceclofenac is well absorbed. The maximum concentration is reached after 1.25 - 3 hours. Aceclofenac enters the joint fluid, where its content reaches 57% of plasma concentrations, and the maximum concentration is timeThe dose is reached 2 to 4 hours longer than in plasma. The distribution volume of aceclofenac is 25 liters. Aceclofenac binds to plasma proteins (albumin) by 99%. Aceclofenac circulates mainly unchanged, its main metabolite is 4'-hydroxyaceclofenac. the half-life is 4 hours. Aceclofenac is excreted by the kidneys, more than 60% in the form of hydroxy derivatives.
Indications
The drug is prescribed: as a part of the complex treatment of inflammatory diseases of the musculoskeletal system (osteoarthritis, rheumatoid, psoriatic and juvenile arthritis, gifts, ankylosing spondylitis or spondylitis)
for the relief of pain syndrome toothache, humeroscapular periarthritis.
Aceclofenac is not able to completely cure these diseases, but it quickly reduces inflammation and pain.
Contraindications
The medicine is contraindicated: for allergies to the active substance
to patients with ulcers and erosion in the digestive tract, during exacerbation of
in Crohn’s disease and ulcerative colitis
if there is a suspicion of bleeding from the gastrointestinal tract
in severe liver diseases and liver failure
in pregnant women
in patients with impaired hematopoiesis or blood clotting
during hypercalcea , progressive kidney disease
for children under 18
during the recovery period after coronary artery bypass grafting
with the “aspirin triad”
to individuals suffering from severe heart failure.
Caution should be observed: for kidney disease, of the gastrointestinal tract and liver of moderate and mild severity
if the patient has the helicobacter bacterium in the gastrointestinal tract
for bronchial asthma
for people with low blood pressure
after extensive surgery if the circulating blood volume
is reduced in elderly patients
cerebrovascular disease
in diabetes mellitus
after prolonged treatment of NSAIDs
for alcoholics and smokers
in severe somatic diseases
in patients with hemostatic defects
with stemnoy lupus erythematosus
combined with anticoagulants, serotonin reuptake inhibitors, antiplatelet.
Ointment or cream should not be applied to damaged skin.
Use during pregnancy and lactation
An absolute contraindication to the use of the product is the 3rd trimester of pregnancy.
Special care must be taken in the 1st and 2nd trimesters and during breastfeeding. The medicine can be prescribed by a doctor in case of urgent need.
Special instructions
It is recommended to use minimally effective and active dosages as a precaution during treatment with the drug. Periodic monitoring of the liver and kidneys, a picture of peripheral blood, feces (lack of blood), and the work of the cardiovascular system are also shown.
During treatment, you must not drive or perform potentially hazardous activities.
The risk of allergies or skin reactions is higher in the first months of taking the medicine. If there are injuries of the oral mucosa, skin rashes, other signs of allergy, then therapy should be interrupted.
The process of inhibition of platelets during treatment with the drug is reversible, the composition of the blood normalizes some time after drug withdrawal.
Composition
Active ingredients:
Aceclofenac - 100 mg
Excipients:
Core composition:
Calcium stearate - 3 mg
talc - 9 mg
Silicon colloidal dioxide (aerosil) - 1.5 mg
Microcrystalline cellulose - 85 mg
Croscarmellose sodium (primrose) - 10.5 mg
Lactose monohydrate (91 mg) (
Core mass - 300 mg
Shell composition:
Hypromellose (hydroxypropyl methylcellulose) - 6.4 mg
Macrogol - 4000 (polyethylene oxide-4000) - 2.5 mg
Titanium dioxide (titanium dioxide) - 1.1 mg
Tablet weight - 310 mg
Dosage and Administration
Tablets are prescribed by mouth. Depending on the disease and age of the patient, 100 to 200 mg of the drug per day is prescribed. 100 mg at a time, whole, without separation and without chewing, with a large amount of liquid.
Outwardly. The substance in the composition of the ointment or cream with a thin layer is carefully applied to the area of ​​inflammation 3 times a day. After using the drug, it is recommended to wash your hands thoroughly with soap, to prevent contact with eyes.
Side effects of
During Aceclofenac treatment, dizziness, nausea, abnormalities in the gastrointestinal tract, abdominal pain, indigestion, diarrhea
increase in liver enzyme activity, allergic reactions in the form of skin rashes and itching are often observed.
Less commonly developed: anemia, anaphylactic reactions, decreased visual acuity
increased blood pressure, heart failure, dyspnea
increased concentration of creatinine and urea in the blood
constipation, oral ulcers, increased gas formation, gastritis, gastric vomiting, hematitis, vomiting,
ulcer
dermatitis, itching, Quincke's edema, urticaria.
Very rarely occur: muscle cramps, weakness and a feeling of fatigue, weight gain, hyperkalemia, eczema
renal failure, nephrotic syndrome, purpura
nephritis, Stevens-Johnson syndrome, chicken pox soft tissue infections, toxic epidermal necrolysis of
granulocytopenia, impaired hematopoiesis, thrombocytopenia, hemolytic anemia
depression, vivid dreams and nightmares, nightmares, nightmares , vasculitis
tremor, taste perversion, drowsiness, paresthesia, tinnitus
perforation of the intestines, pancreatitis, ulcerative colitis, vomiting with blood
hyperemia of the skin, hot flashes, tachycardia
bronchospasm, stomatitis, hepatitis.
Drug Interactions
Anticoagulants when combined with tablets increase the risk of bleeding. During treatment, it is recommended to periodically monitor blood coagulation.
Aceclofenac tablets increase the plasma concentration of digoxin, phenytoin, lithium-based drugs.
The substance when combined with antihypertensive drugs and diuretics reduces the effectiveness of the latter.
The combination of the drug with potassium-sparing diuretics increases the likelihood of hyperkalemia.
With caution, the drug should be combined with NSAIDs and glucocorticosteroids, the drug increases the toxicity of methotrexate and cyclosporine.
Aspirin reduces the plasma concentration of aceclofenac.
The combination of drugs with hypoglycemic drugs requires constant monitoring of blood glucose levels.
Overdose
There have been no reported cases of drug overdose in humans.
Overdose symptoms are: headaches, cramps, vomiting, abdominal pain, nausea, dizziness. Enterosorbents are used as therapy, they wash the stomach and produce symptomatic treatment. The drug does not have a specific antidote, hemodialysis and forced diuresis are ineffective.
Storage conditions
Tablets are stored in a cool, dark place, away from children.
Expiration
3 years.
Deystvuyuschee substances
Aceclofenac
Conditions of supply of pharmacies
prescription
Form of Treatment
tablets
Appointment
Adult prescription, For athletes
Possible Product Names
Aceclofenac Tablets. 100 mg 20 pcs.
Aceclofenac tablets coated.pl.ob. 100 mg 20 pcs. (Aceclofenac) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Aceclofenac tablets coated.pl.ob. 100 mg 20 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
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