Arbidol Maximum capsules 200 mg, 10 pcs. (Umyfenovyr)

Latin name

Arbidol Maximum

Release form

Capsules.



packaging 10 pcs

Pharmacological action

Arbidol Maximum - antiviral and immunostimulating agent.

Pharmacodynamics.

An antiviral agent that has an immunomodulating and anti-influenza effect, specifically inhibits influenza A and B viruses, a severe acute respiratory syndrome (SARS).

Prevents the contact and penetration of viruses into the cell, inhibiting the fusion of the lipid membrane of the virus with cell membranes. It has an interferon-inducing effect, stimulates humoral and cellular immune responses, the phagocytic function of macrophages, and increases the body's resistance to viral infections. It reduces the incidence of complications associated with a viral infection, as well as exacerbations of chronic bacterial diseases.

Therapeutic efficacy in viral infections is manifested in a decrease in the severity of general intoxication and clinical events, and a reduction in the duration of the disease.

Refers to low-toxic drugs (LD50> 4 g / kg). It does not have any negative effects on the human body when administered orally in recommended doses.

Pharmacokinetics

Quickly absorbed and distributed to organs and tissues. The maximum concentration in blood plasma when taken at a dose of 50 mg is reached after 1.2 hours, at a dose of 100 mg - after 1.5 hours. It is metabolized in the liver. The elimination half-life is 17-21 hours. About 40% is excreted unchanged, mainly with bile (38.9%) and in a small amount by the kidneys (0.12%). During the first day, 90%) of the administered dose is excreted.

Indications

Prevention and treatment in adults and children: influenza A and B, SARS, severe acute respiratory syndrome (SARS) (including those complicated by bronchitis, pneumonia) secondary immunodeficiency conditions, complex therapy of chronic bronchitis, pneumonia and recurrent herpetic infection.

Prevention of postoperative infectious complications and normalization of immune status.

Complex therapy of acute intestinal infections of rotavirus etiology in children older than 3 years.

Contraindications

Hypersensitivity to the drug, age up to 3 years.

Special instructions

Effect on the ability to drive vehicles and other mechanisms, requiring increased concentration of attention

Does not show central neurotropic activity and can be used in medical practice as a preventive measure in healthy individuals of various professions, including requiring increased attention and coordination of movements (drivers of transport, operators, etc.).

Composition

1 capsule contains:

p active.

Dosage and administration

Inside, before meals.

Single dose: for children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg (2 capsules of 100 mg or 4 capsules of 50 mg).

For non-specific prophylaxis:

In direct contact with patients with influenza and other acute respiratory viral infections:

for children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg once a day for 10-14 days.

During the period of the epidemic of influenza and other acute respiratory viral infections, to prevent exacerbations of chronic bronchitis, relapse of herpes infection:

for children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg twice a week for 3 weeks.

For the prevention of SARS (in contact with the patient):

is prescribed to adults and children over 12 years of age 200 mg once a day. Children from 6 to 12 years of age, 100 mg once a day (before meals) for 12-14 days.

Prevention of postoperative complications:

for children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 2 days before surgery, then 2 and 5 days after surgery.

For treatment:

Influenza, other acute respiratory viral infections without complications:

for children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 4 times a day (every 6 hours) for 5 days.

Influenza, other acute respiratory viral infections with the development of complications (bronchitis, pneumonia, etc.):

for children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 4 times a day ( every 6 hours) for 5 days, then a single dose 1 time per week for 4 weeks.

Severe Acute Respiratory Syndrome (SARS):

for children over 12 years of age and adults - 200 mg 2 times a day for 8-10 days.

In the complex treatment of chronic bronchitis, herpetic infection:

for children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg 4 times a day (every 6 hours) for 5 -7 days, then a single dose 2 times a week for 4 weeks.

Complex therapy of acute intestinal infections of rotavirus etiology in children older than 3 years:

from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, older than 12 years old - 200 mg 4 times a day (every 6 hours) for 5 days.

Side effects

Rarely - allergic reaction.

Drug Interactions

No adverse effects were observed with other drugs.

Storage Conditions

Store in a dry, dark place.

Expiration

2 years.

active substance

umifenovir

Dosage form

capsule

Prescribing

Children over 12 years old, For adults

Indications

Indications

Indications

Colds, SARS, Influenza, Prevention of influenza and the common cold

Pharmstandard-Leksredstva, Russia



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