Ascorbic acid with glucose tablets, 10 pcs. (ascorbic acid, dextrose)

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Release form

Tablets. Buy Ascorbic acid with glucose tablets, 10 pcs. (ascorbic acid, dextrose) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Release form

Tablets.

Packing

Per pack 10 pcs.

Pharmacological action of

Pharmacodynamics of

Ascorbic acid with glucose is a vitamin product, has a metabolic effect, is involved in the regulation of redox processes, carbohydrate metabolism, blood coagulation, tissue regeneration, in the synthesis of steroid hormones increases the body's resistance to infections, reduces vascular permeability, reduces the need for vitamins B1, B2, A, E, folic acid, pantothenic acid.

Pharmacokinetics

Ascorbic acid is well absorbed mainly in the duodenum and jejunum. 30 minutes after the administration, the content of ascorbic acid in the blood noticeably increases, and its intense uptake by tissues begins due to its initial conversion into dehydroascorbic acid, which has the ability to penetrate through cell membranes without energy costs and quickly recover in the cell. Intracellular ascorbic acid is determined in three forms - ascorbic and dehydroascorbic acids and ascorbigen (bound ascorbic acid).

The distribution between organs is uneven: there are many in the endocrine glands, especially in the adrenal glands, less in the brain, kidneys, liver, cardiac and skeletal muscles. Ascorbic acid is partially metabolized and excreted by up to 90% of the kidneys in the form of oxalate, partly in the free form. Glucose is easily absorbed, the main metabolic pathways are glycolysis and aerobic oxidation with the formation of carbon dioxide and water with the release of ATP and other macroergic compounds.

Contraindications

Hypersensitivity,

children under 6 years of age,

thrombophlebitis,

tendency to thrombosis.

Precautions

Diabetes mellitus, glucose-6-phosphate dehydrogenase deficiency for large doses - hemochromatosis, sideroblastic anemia, thalassemia, hyperoxaluria, nephrourolithiasis.

Use during pregnancy and lactation

During pregnancy and lactation, use only if the intended benefits to the mother outweigh the risk to the fetus and baby. During pregnancy and lactation, ascorbic acid is taken only as directed by a doctor. The daily need for ascorbic acid in the II-III trimesters of pregnancy is 90-100 mg. Keep in mind that the fetus can adapt to high doses of ascorbic acid, which is taken by a pregnant woman, and then the newborn may develop the “withdrawal” syndrome.

Theoretically, there is a danger to the child when a high dose of ascorbic acid is used by the nursing mother (it is recommended not to exceed the daily requirement of ascorbic acid by the nursing mother). Recommended daily need for ascorbic acid during lactation is 120 mg.

Special instructions

In connection with the stimulating effect of ascorbic acid on the synthesis of corticosteroid hormones, it is necessary to monitor renal function and blood pressure. With prolonged use of large doses, inhibition of the function of the insular apparatus of the pancreas is possible, therefore, during treatment it must be regularly monitored.

In patients with a high iron content in the body, ascorbic acid should be used in minimal doses.

The administration of ascorbic acid to patients with rapidly proliferating and intensively metastatic tumors may aggravate the course of the process.

Ascorbic acid as a reducing agent can distort laboratory test results (blood glucose, bilirubin, activity of “liver” transaminases and LDH).

Dosage and Administration

Inside. In terms of ascorbic acid:

- for adults with prophylactic purpose - 50-100 mg / day, for children 6-14 years old - 50 mg of ascorbic acid per day, for children over 14 years old - 50-75 mg of ascorbic acid per day for

- for adults with therapeutic purpose - 50-100 mg 3-5 times a day, for children from 6 years old - 50-100 mg 2-3 times a day. The duration of therapy and dose is determined by the attending physician.

Side effects of

Allergic reactions, irritation of the gastrointestinal mucosa (gastrointestinal tract) (nausea, vomiting, diarrhea, gastrointestinal spasm) inhibition of the function of the pancreatic insular apparatus (hyperglycemia, glucosuria) when used in high doses - nephrocalcinosis and hypercalcallosalus )

Change in laboratory parameters: thrombocytosis, hyperprombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia.

Drug interaction

Ascorbic acid increases the blood concentration of benzylpenicillin and tetracyclines at a dose of 1 g / day and increases the bioavailability of ethinyl estradiol (including that which is part of oral contraceptives).

Improves the absorption of iron preparations in the intestines, can increase the excretion of iron while using deferoxamine.

Reduces the effectiveness of heparin and indirect anticoagulants.

Acetylsalicylic acid, oral contraceptives, fresh juices and alkaline drink reduce absorption and absorption.

Increases the risk of crystalluria in the treatment of short-acting salicylates and sulfanilamides, slows the excretion of acids by the kidneys, increases the excretion of drugs with an alkaline reaction (including alkaloids, reduces the concentration of oral contraceptives in the blood).

Increases the total clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body.

In high doses, increases the excretion of mexiletine by the kidneys.

Barbiturates increase urinary excretion of ascorbic acid.

Reduces the therapeutic effect of antipsychotic drugs (antipsychotics) - phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants.

Overdose

Symptoms: when used more than 1 g - headache, increased excitability of the CNS, insomnia, nausea, vomiting, diarrhea, hyperacid gastritis, ulceration of the gastrointestinal mucosa, suppression of the function of the pancreas insular apparatus (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis (calcium oxalate), damage to the glomerular kidney apparatus, moderate pollakia (more than 600 mg / day). Reduction of capillary permeability (possible deterioration of tissue trophic, increase of blood pressure (BP), hypercoagulation, development of microangiopathies).

Storage conditions

In a place protected from light and moisture, at a temperature not exceeding 25 C. Keep out of reach of children.

Active ingredient

Ascorbic acid, D ectrose

Terms leave through pharmacies

without prescription

lekarstvennaja form

tablets

Appointment

Vitamins and minerals

Possible product names

Ascorbic acid with glucose Meligen tab 1g N10 pack boom (PARTY 50pcs)

Ascorbic acid with glucose tablets, 10 pcs.

Meligy, Russia



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