Azitrox suspension 100 mg / 5 ml, 20 ml (Azithromycin)

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Release form

Packing

Bottle 20 ml.

Pharmacological action

Azitrox® is a broad-spectrum antibiotic. It is the first representative of a new subgroup of macrolide antibiotics - azalides. When creating high concentrations of inflammation in the focus, it has a bactericidal effect.

Gram-positive cocci are sensitive to azithromycin: Streptococcus pneumoniae, St. pyogenes, St. agalactiae, streptococci of CF and G groups, Staphylococcus aureus, St. Viridans are Gram-negative bacteria: Haemophilus influenzae, Moraxella catarrhalis, Bordetella pertussis, B. parapertussis, Legionella pneumophila, H. ducrei, Campylobacter jejuni, Neisseria gonorrhoeae and Gardnerella microorganisms, microorganisms, microorganisms, microorganisms, pneumoniae, Ureaplasma urealyticum, Treponema pallidum, Borrelia burgdoferi. Azithromycin is inactive against gram-positive bacteria resistant to erythromycin.

Azithromycin persists in bactericidal concentrations in the focus of inflammation for 5-7 days after the last dose, which allowed the development of short (3-day and 5-day) courses of treatment.

Indications

- Infectious and inflammatory diseases, caused by microorganisms sensitive to the drug:

- Upper respiratory tract infections and ENT organs (tonsillitis, sinusitis, tonsillitis, otitis media)

- Scarlet fever

- Lower respiratory tract infections (bacterial and SARS, bronchitis)

- Skin infections soft tissues (erysipelas, impetigo, secondarily infected dermatoses)

- Infections of the urogenital tract (uncomplicated urethritis and / or cereitis)

- Lyme disease (borreliosis), for the treatment of the initial stage (erithema migrans)

- Disease of the stomach and twelve erstnoy ulcers associated with Helicobacter Pylori.

Contraindications

Hypersensitivity to azithromycin and other macrolide antibiotics.

Use during pregnancy and lactation

Azithromycin crosses the placental barrier. Use during pregnancy is possible only in cases where the intended benefits to the mother outweigh the potential risk to the fetus.

If you need to use azithromycin during lactation, you should decide whether to stop breastfeeding.

Special instructions

Not recommended for use in patients with impaired liver function.

Use with caution in cases of impaired renal function.

Azithromycin should be taken at least 1 hour before or 2 hours after a meal or antacids.

Composition

5 ml of the finished suspension contains:

azithromycin 100 mg.

Dosage and administration

Set individually, taking into account the nosological form, the severity of the disease and the sensitivity of the pathogen.

Adults inside - 0.25-1 g 1 time / day for children - 5-10 mg / kg 1 time / day. Duration of administration is 2-5 days.

Side effects of the

From the digestive system: nausea, vomiting, flatulence, diarrhea, abdominal pain, transient increase in the activity of liver enzymes rarely - cholestatic jaundice.

Allergic reactions: rarely - skin rash, angioedema, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.

Dermatological reactions: rarely - photosensitivity.

From the side of the central nervous system: dizziness, headache rarely - drowsiness, weakness.

From the hemopoietic system: rarely - leukopenia, neutropenia, thrombocytopenia.

From the cardiovascular system: rarely - chest pain.

From the genitourinary system: vaginitis rarely - candidiasis, nephritis, increased residual urea nitrogen.

Other: rarely - hyperglycemia, arthralgia.

Drug Interactions

When used together with ergot alkaloids, the risk of ergotism cannot be ruled out.

With the simultaneous use of azithromycin with warfarin, cases of increased effects of the latter have been described.

With the simultaneous use of digoxin or digitoxin with azithromycin, a significant increase in the concentration of cardiac glycosides in blood plasma and a risk of developing glycoside intoxication are possible.

With simultaneous use with disopyramide, a case of ventricular fibrillation has been described.

With simultaneous use with lovastatin, cases of rhabdomyolysis have been described.

When used concomitantly with rifabutin, the risk of developing neutropenia and leukopenia is increased.

With simultaneous use, cyclosporin metabolism is disrupted, which increases the risk of adverse and toxic reactions caused by cyclosporine.

Storage conditions

In a dry, dark place at room temperature.

Keep out of the reach of children.

Expiration

2 years. Prepared suspension - no more than 5 days.

Deystvuyuschee substances

Azithromycin

Form of Treatment

suspension dlya accepts vnutry

Appointment

Adult prescribing, Prescribing children, Children older than 6 months

Indications

Bronchitis, Infectious diseases, Inflammation l lung infections, respiratory tract infections, pharyngitis, sinusitis, cystitis, tonsillitis, tonsillitis, otitis media, urethritis, skin infections

Possible product names

AZITROX 0, 1 / 5ML 20ML N1 FLAC POR D / SUSP VN

Azitrox por d / suspension d / inside approx. 100mg / 5ml 15.9g fl + mern. Spoon + pipette doses ind unit *

Azitrox p d / suspension d / inside approx. 100mg / 5ml 15.9g fl + mern spoon + pipette doses ind unitary enterprise

AZITROX POR. D / PRIG. SUSP. D / RECEPTION INSIDE 100MG / 5ML 20ML (15.9G) FL. No. 1

Azitrox Pore. d / preparation. suspension for oral administration vial 100mg / 5ml 15.9g Russia

Pharmstandard-Leksredstva, Russia



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