Baraclude tablets 1 mg, 30 pcs. (entekavyr)

Release form

Film-coated tablets.

Packing

30 pcs

Pharmacological action

Baraclude has an antiviral effect.

Indications

Chronic hepatitis B in adults with signs of viral replication and increased activity of serum transaminases (ALT or AST) or in the presence of histological signs of an inflammatory process in the liver.

Contraindications

Hypersensitivity to entecavir or any other component of the drug. Children's age: up to 18 years.

Use during pregnancy and lactation

Adequate and well-controlled studies in pregnant women have not been conducted.

Baraclude can be taken during pregnancy if the potential benefit of the application outweighs the potential risk to the fetus.

There is no data on the penetration of entecavir into breast milk.

Breastfeeding is not recommended when using the drug.

Composition

1 tab. contains entecavir 1 mg.

Dosage and administration of

Baraclude should be taken orally on an empty stomach (that is, at least 2 hours after eating and no later than 2 hours before the next meal).

The recommended dose of entecavir is 0.5 mg once daily. Patients resistant to lamivudine (that is, patients with a history of hepatitis B virus viremia remaining with lamivudine therapy, or patients with confirmed resistance to lamivudine) should be prescribed 1 mg entecavir once a day.

Patients with renal failure: Entecavir clearance decreases with decreased creatinine clearance.

Recommended dose adjustment of entecavir to patients with creatinine clearance <50 ml / min, including those on hemodialysis and long-term ambulatory peritoneal dialysis.

Entecavir should be taken after a hemodialysis session.

In patients with hepatic insufficiency, dose adjustment of entecavir is not required.

Side effects of the

From the digestive system: rarely ( 1/1000, <1/100) - diarrhea, dyspepsia, nausea, vomiting.

From the side of the central nervous system: often ( 1/100, <1/10) - headache, rarely fatigue ( 1/1000, <1/100) - insomnia, dizziness, drowsiness.

Post-marketing data (frequency cannot be determined)

Allergic reactions: anaphylactoid reaction.

Dermatological reactions: alopecia, rash.

Storage Conditions

At a temperature not exceeding 25 ° C.

active substance

Entecavir

Terms leave through pharmacies

In retseptu

The dosage form of

tablet

Prescribing

For adults as prescribed by a doctor

Indications

Indications srdl0164 Liver score waf Indications

Indications

Damage to the liver, Hepatitis

bris ol-Myers Squibb, USA



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