Bisoprolol-SZ tablets coated. 10 mg film, 50 pcs. (bisoprolol)
Special Price
$20.40
Regular Price
$24.00
In stock
SKU
newyork502861
Release form
film-coated tablets. Buy Bisoprolol-SZ tablets coated. 10 mg film, 50 pcs. (bisoprolol) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
film-coated tablets. Buy Bisoprolol-SZ tablets coated. 10 mg film, 50 pcs. (bisoprolol) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Release form
film-coated tablets.
Packing
50 pcs.
Pharmacological action
Bisoprolol is a selective beta1-blocker without internal sympathomimetic activity, does not have membrane-stabilizing activity. Bisoprolol reduces plasma renin activity, reduces myocardial oxygen demand, reduces heart rate (at rest and during exercise) and cardiac output, while stroke volume does not significantly decrease. Inhibits AV conduction. It has antianginal and hypotensive effects. In high doses (200 mg or more), it can cause blockade and 2-adrenoreceptors mainly in the bronchi and in the smooth muscles of blood vessels.
Contraindications
Chronic heart failure II B - stage III, cardiogenic shock, AV block II and III degree, CVD, sinoatrial block, bradycardia, arterial hypotension (systolic pressure less than 90 mm Hg) tendency to bronchospasm ( and other diseases with bronchial obstructive syndrome), severe peripheral circulatory disorders, concomitant use of MAO inhibitors (with the exception of MAO inhibitors of type B), increased sensitivity to bisoprolol and other beta-adrenoblock Ram pregnancy and lactation.
Special instructions
Use with caution in case of psoriasis and for indications of psoriasis in the family history, diabetes mellitus in the decompensation phase, with a predisposition to allergic reactions. With pheochromocytoma, the use of bisoprolol is possible only after taking alpha-blockers. To prevent the sudden withdrawal of bisoprolol, the course of treatment should be completed slowly with a gradual decrease in dose.
Composition
1 tablet contains bisoprolol (in the form of a fumarate) 10 mg.
Dosage and administration
Dosage regimen is individual. For oral administration, the daily dose of bisoprolol is 2.5-10 mg, the frequency of administration is 1 time / day. The maximum daily dose is 10 mg.
Side effects of
From the side of the central nervous system and peripheral nervous system: weakness, fatigue, dizziness, headache, sleep disorders, mental disorders (depression, rarely hallucinations), a feeling of cold and paresthesia in the limbs.
From the cardiovascular system: orthostatic hypotension, bradycardia, impaired AV conduction, the appearance of symptoms of heart failure, worsening intermittent claudication and the main clinical symptoms in Raynaud's syndrome.
From the side of the organ of vision: decreased secretion of lacrimal fluid, conjunctivitis.
From the digestive system: diarrhea, constipation, nausea, abdominal pain.
From the musculoskeletal system: muscle weakness, muscle cramps.
Drug Interactions
Allergens used for immunotherapy, or allergen extracts for skin tests increase the risk of severe systemic allergic reactions or anaphylaxis in patients receiving bisoprolol.
Iodine-containing radiopaque drugs for iv administration increase the risk of anaphylactic reactions.
Phenytoin with iv administration, drugs for inhalation general anesthesia (hydrocarbon derivatives) increase the severity of cardiodepressive action and the likelihood of lowering blood pressure.
Changes the effectiveness of insulin and oral hypoglycemic drugs, masks the symptoms of developing hypoglycemia (tachycardia, increased blood pressure).
Reduces clearance of lidocaine and xanthines (except diphillin) and increases their concentration in plasma, especially in patients with initially increased clearance of theophylline under the influence of smoking.
The antihypertensive effect is weakened by NSAIDs (Na + retention and blockade of prostaglandin synthesis by the kidneys), GCS and estrogens (Na + ion retention).
Cardiac glycosides, methyldopa, reserpine and guanfacine, slow calcium channel blockers (verapamil, diltiazem), amiodoron, and other antiarrhythmic drugs increase the risk of developing or worsening bradycardia, AV blockade, heart failure, and heart failure.
Nifedipine can lead to a significant decrease in blood pressure.
Diuretics, clonidine, sympatholytics, hydralazine and other antihypertensive drugs can lead to an excessive decrease in blood pressure.
Extends the effect of non-depolarizing muscle relaxants and the anticoagulant effect of coumarins.
Tri- and tetracyclic antidepressants, antipsychotic drugs (antipsychotics), ethanol, sedative and hypnotic drugs increase CNS depression.
The simultaneous use with MAO inhibitors is not recommended due to a significant increase in the antihypertensive effect, the break in treatment between taking MAO inhibitors and bisoprolol should be at least 14 days.
Non-hydrogenated ergot alkaloids increase the risk of peripheral circulation disorders.
Ergotamine increases the risk of developing peripheral circulatory disorders sulfasalazine increases the plasma concentration of bisoprolol rifampicin shortens the elimination half-life.
overdose
Symptoms: arrhythmia, ventricular extrasystole, severe bradycardia, AV blockade, severe BP, chronic heart failure, finger or palm cyanosis, difficulty breathing, bronchospasm dizziness, fainting, convulsions.
Treatment: gastric lavage and the appointment of adsorbents symptomatic therapy: with developed AV blockade - in / in the introduction of 1-2 mg of atropine, epinephrine or the setting of a temporary pacemaker with ventricular extrasystole - lidocaine (class IA drugs should not be used) with lowering in the position of Trendelenburg if there is no evidence of pulmonary edema - in / in plasma-replacement solutions, with inefficiency - the introduction of epinephrine, dopamine, dobutamine (to maintain chronotropic and inotropic action and eliminate in pronounced decrease in blood pressure) in heart failure - cardiac glycosides, diuretics, glucagon in convulsions - in / in diazepam with bronchospasm beta-blockers inhalation.
Storage conditions
Store in a dry, dark place out of the reach of children, at temperatures not exceeding 20 ° C.
Shelf life
3 years.
Deystvuyushtee substance
Bisoprolol
Terms and conditions
prescription
dosage form
tablets
Bisoprolol-SZ tablets coated. 10 mg film, 50 pcs. (bisoprolol) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Bisoprolol-SZ tablets coated. 10 mg film, 50 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
film-coated tablets.
Packing
50 pcs.
Pharmacological action
Bisoprolol is a selective beta1-blocker without internal sympathomimetic activity, does not have membrane-stabilizing activity. Bisoprolol reduces plasma renin activity, reduces myocardial oxygen demand, reduces heart rate (at rest and during exercise) and cardiac output, while stroke volume does not significantly decrease. Inhibits AV conduction. It has antianginal and hypotensive effects. In high doses (200 mg or more), it can cause blockade and 2-adrenoreceptors mainly in the bronchi and in the smooth muscles of blood vessels.
Contraindications
Chronic heart failure II B - stage III, cardiogenic shock, AV block II and III degree, CVD, sinoatrial block, bradycardia, arterial hypotension (systolic pressure less than 90 mm Hg) tendency to bronchospasm ( and other diseases with bronchial obstructive syndrome), severe peripheral circulatory disorders, concomitant use of MAO inhibitors (with the exception of MAO inhibitors of type B), increased sensitivity to bisoprolol and other beta-adrenoblock Ram pregnancy and lactation.
Special instructions
Use with caution in case of psoriasis and for indications of psoriasis in the family history, diabetes mellitus in the decompensation phase, with a predisposition to allergic reactions. With pheochromocytoma, the use of bisoprolol is possible only after taking alpha-blockers. To prevent the sudden withdrawal of bisoprolol, the course of treatment should be completed slowly with a gradual decrease in dose.
Composition
1 tablet contains bisoprolol (in the form of a fumarate) 10 mg.
Dosage and administration
Dosage regimen is individual. For oral administration, the daily dose of bisoprolol is 2.5-10 mg, the frequency of administration is 1 time / day. The maximum daily dose is 10 mg.
Side effects of
From the side of the central nervous system and peripheral nervous system: weakness, fatigue, dizziness, headache, sleep disorders, mental disorders (depression, rarely hallucinations), a feeling of cold and paresthesia in the limbs.
From the cardiovascular system: orthostatic hypotension, bradycardia, impaired AV conduction, the appearance of symptoms of heart failure, worsening intermittent claudication and the main clinical symptoms in Raynaud's syndrome.
From the side of the organ of vision: decreased secretion of lacrimal fluid, conjunctivitis.
From the digestive system: diarrhea, constipation, nausea, abdominal pain.
From the musculoskeletal system: muscle weakness, muscle cramps.
Drug Interactions
Allergens used for immunotherapy, or allergen extracts for skin tests increase the risk of severe systemic allergic reactions or anaphylaxis in patients receiving bisoprolol.
Iodine-containing radiopaque drugs for iv administration increase the risk of anaphylactic reactions.
Phenytoin with iv administration, drugs for inhalation general anesthesia (hydrocarbon derivatives) increase the severity of cardiodepressive action and the likelihood of lowering blood pressure.
Changes the effectiveness of insulin and oral hypoglycemic drugs, masks the symptoms of developing hypoglycemia (tachycardia, increased blood pressure).
Reduces clearance of lidocaine and xanthines (except diphillin) and increases their concentration in plasma, especially in patients with initially increased clearance of theophylline under the influence of smoking.
The antihypertensive effect is weakened by NSAIDs (Na + retention and blockade of prostaglandin synthesis by the kidneys), GCS and estrogens (Na + ion retention).
Cardiac glycosides, methyldopa, reserpine and guanfacine, slow calcium channel blockers (verapamil, diltiazem), amiodoron, and other antiarrhythmic drugs increase the risk of developing or worsening bradycardia, AV blockade, heart failure, and heart failure.
Nifedipine can lead to a significant decrease in blood pressure.
Diuretics, clonidine, sympatholytics, hydralazine and other antihypertensive drugs can lead to an excessive decrease in blood pressure.
Extends the effect of non-depolarizing muscle relaxants and the anticoagulant effect of coumarins.
Tri- and tetracyclic antidepressants, antipsychotic drugs (antipsychotics), ethanol, sedative and hypnotic drugs increase CNS depression.
The simultaneous use with MAO inhibitors is not recommended due to a significant increase in the antihypertensive effect, the break in treatment between taking MAO inhibitors and bisoprolol should be at least 14 days.
Non-hydrogenated ergot alkaloids increase the risk of peripheral circulation disorders.
Ergotamine increases the risk of developing peripheral circulatory disorders sulfasalazine increases the plasma concentration of bisoprolol rifampicin shortens the elimination half-life.
overdose
Symptoms: arrhythmia, ventricular extrasystole, severe bradycardia, AV blockade, severe BP, chronic heart failure, finger or palm cyanosis, difficulty breathing, bronchospasm dizziness, fainting, convulsions.
Treatment: gastric lavage and the appointment of adsorbents symptomatic therapy: with developed AV blockade - in / in the introduction of 1-2 mg of atropine, epinephrine or the setting of a temporary pacemaker with ventricular extrasystole - lidocaine (class IA drugs should not be used) with lowering in the position of Trendelenburg if there is no evidence of pulmonary edema - in / in plasma-replacement solutions, with inefficiency - the introduction of epinephrine, dopamine, dobutamine (to maintain chronotropic and inotropic action and eliminate in pronounced decrease in blood pressure) in heart failure - cardiac glycosides, diuretics, glucagon in convulsions - in / in diazepam with bronchospasm beta-blockers inhalation.
Storage conditions
Store in a dry, dark place out of the reach of children, at temperatures not exceeding 20 ° C.
Shelf life
3 years.
Deystvuyushtee substance
Bisoprolol
Terms and conditions
prescription
dosage form
tablets
Bisoprolol-SZ tablets coated. 10 mg film, 50 pcs. (bisoprolol) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Bisoprolol-SZ tablets coated. 10 mg film, 50 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
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