Calcium chloride ampoules 10%, 10 ml, 10 pcs. (calcium chloride)

Pharmacological action

Calcium chloride is a calcium preparation that replenishes the calcium deficiency necessary for the process of transmission of nerve impulses, reduction of skeletal and smooth muscles, myocardial activity, formation of bone tissue, blood coagulation.

Reduces the permeability of cells and the vascular wall, prevents the development of inflammatory reactions, increases the body's resistance to infections and can significantly increase phagocytosis (phagocytosis, which decreases after taking sodium chlorine, increases after taking calcium preparations).

When administered intravenously, it stimulates the sympathetic division of the autonomic nervous system, enhances adrenal gland epinephrine, and has a moderate diuretic effect.

Pharmacokinetics of

In plasma, about 45% is in complex with proteins. About 20% is excreted by the kidneys, the remaining amount (80%) is removed with the contents of the intestine.

Indications

Bleeding of various etiologies and localizations (pulmonary, gastrointestinal, nasal, uterine, etc.)

allergic diseases (serum sickness, urticaria, febrile syndrome, pruritus, Quincke's edema)

dystrophic alimentary infections, alimentary infections, hypocalcemia,

increased vascular permeability (hemorrhagic vasculitis, radiation sickness),

weakness of labor,

poisoning with magnesium salts, oxalic and fluoric acids: paroxysmal myoplegia (hypercal hemic form).

Contraindications

Hypersensitivity,

hypercalcemia,

atherosclerosis,

tendency to thrombosis.

Composition of

1 ml of solution for intravenous administration contains: active ingredient:

calcium chloride 100 mg,

excipient:

water for injection

Dosage and administration

Slowly intravenously (6-8 drops / min), 5-15 ml of 10% solution, diluting before administration in 100-200 ml of 0.9% NaCl solution or 5% dextrose solution.

Side effects of

When administered intravenously - a feeling of heat, flushing of the face, bradycardia, with rapid administration - ventricular fibrillation.

Local reactions (with intravenous administration) - pain and hyperemia along the vein.

Drug interaction

When combined with thiazide diuretics, it can enhance hypercalcemia, reduce the effect of calcitonin with hypercalcemia, and reduce the bioavailability of phenytoin.

dosage form

infusion solution

Indications

hives, itchy skin, Angioedema

Armavirskaya biofabrika, Russia



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