Candide cream 1%, 20 g (Clotrimazole)

Release form

Topical cream

Pharmacological action

Candide is a broad-spectrum antifungal.

The antimycotic effect of the active substance, clotrimazole (an imidazole derivative), is associated with impaired synthesis of ergosterol, which is part of the cell membrane of fungi, which changes the membrane permeability and causes subsequent cell lysis.

It acts fungistatically in small concentrations, fungicidal in large concentrations, and not only on proliferating cells.

In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, resulting in an increase in the concentration of hydrogen peroxide to a toxic level, which also contributes to the destruction of fungal cells.

Effective against dermatophytes, yeast-like and mold fungi, as well as the causative agent of colorful lichen (Pityriasis versicolor) and the pathogen of erythrasma. It has an antimicrobial effect against gram-positive (staphylococci, streptococci) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as against Trichomonas vaginalis.

Indications

dermatophytosis of the head (including the face), body, foot

mycosis of nails

multicolored lichen

candidiasis of the skin

candida paronychia

candida vulvitis

candida balanitis

candidiasis of the external genitalia and anus

fungal diaper dermatitis

.

Contraindications

specific skin lesions (including tuberculosis, chickenpox, herpes simplex, measles, syphilis)

skin reactions at the site of vaccination

hypersensitivity to the components of the drug.

Use during pregnancy and lactation

Safety of the use of the drug Candide during pregnancy and lactation has not been established.

Therefore, the administration of the drug in large quantities or for a long time during these periods should be avoided.

Ingredients

1 g cream contains:

Active ingredient:

Clotrimazole 10 mg

Excipients:

Propylene

Liquid paraffin

cetomacrogol emulsifying wax

White petrolatum

benzyl alcohol

Methylparaben

Propylparaben

Anhydrous sodium phosphate

Sodium phosphate monobasic

butylhydroxytoluene

Purified Water

Dosage and administration

The required amount of cream is rubbed onto previously washed and dry affected skin 2-3 times a day.

Treatment should be continued for another 2-4 weeks after the disappearance of clinical symptoms in order to ensure mycological cure and prevent relapse.

Side effects

Itching, burning and swelling of the vaginal mucosa, vaginal discharge, headache, gastralgia, frequent urination, intercurrent cystitis, burning sensation in the penis of the sexual partner, pain during intercourse.

Overdose

Using the drug at high doses does not cause any life-threatening reactions and conditions.

Symptoms (in case of unintended use of the drug inside):

anorexia, nausea, vomiting, gastralgia, liver dysfunction rarely - drowsiness, hallucinations, pollakuria, skin allergic reactions.

Treatment:

purpose of activated charcoal, if necessary - no symptomatic therapy for a specific antidote.

Storage conditions

The product should be stored in a dry,

, protected from light at a temperature not exceeding 25 ° C.

shelf life

3 years

Deystvuyushtee substance

Clotrimazole

Conditions for dispensing from pharmacies

Without a prescription

dosage form

cream

Possible product names

CANDID 1% 20G. CREAM

Candide 1% Cream 20g

Candide 1% cream d / outdoor approx. 20g Tuba

CANDID 20,0 CREAM

Candide cream 1%, 20 g

Glenmark Pharmaceuticals Ltd., India



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