Candide powder for external use 1%, 30 g (Clotrimazolum)

Latin name

Candid

Release form

Powder for external use

Packaging

Bottle 30 g

Pharmacological action

Candide - a wide spectrum antifungal.

The antimycotic effect of the active active ingredient - clotrimazole (an imidazole derivative) is associated with impaired synthesis of ergosterol, which is part of the cell membrane of fungi, which changes the membrane permeability and causes subsequent cell lysis.

It acts fungistatically in small concentrations, fungicidal in large concentrations, and not only on proliferating cells.

In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, resulting in an increase in the concentration of hydrogen peroxide to a toxic level, which also contributes to the destruction of fungal cells.

Effective against dermatophytes, yeast-like and mold fungi, as well as the causative agent of colorful lichen (Pityriasis versicolor) and the pathogen of erythrasma.

It has antimicrobial activity against gram-positive (staphylococci, streptococci) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as against Trichomonas vaginalis.

Indications

dermatophytosis of the head (including the face), body, foot

mycosis of nails

multicolored lichen

candidiasis of the skin

candida paronychia

candida vulvitis

candida balanitis

candidiasis of the external genitalia and anus

fungal diaper dermatitis

.

Contraindications

specific skin lesions (including tuberculosis, chickenpox, herpes simplex, measles, syphilis)

skin reactions at the site of vaccination

hypersensitivity to the components of the drug.

Composition of

1 g of powder contains:

Active ingredient:

clotrimazole 10 mg

Excipients:

talc purified

corn starch

colloidal silicon dioxide perfume cosmetic.

Dosage and Administration

Externally. Apply to the affected area of ??the skin 3-4 times a day. Improvement occurs in 3-5 days. The duration of therapy is individual and depends on the severity and location of the disease.

To achieve a full recovery, you should not stop treatment with the drug immediately after the disappearance of acute symptoms of inflammation or subjective complaints. The duration of therapy is about 4 weeks.

Pityriasis versicolor is cured mainly within 1-3 weeks, erythrasma - 2-4 weeks.

For fungal diseases of the skin of the legs, it is recommended to continue therapy for about 2 weeks after the relief of the symptoms of the disease.

Side effects

Itching, burning and swelling of the vaginal mucosa, vaginal discharge, headache, gastralgia, frequent urination, intercurrent cystitis, burning sensation in the penis of the sexual partner, pain during intercourse.

Overdose of

The use of the drug in high doses does not cause any reactions and conditions that are life-threatening.

Symptoms (in case of unintended use of the drug by mouth): anorexia, nausea, vomiting, gastralgia, impaired liver function rarely - drowsiness, hallucinations, pollakiuria, skin allergic reactions.

Treatment: administration of activated carbon, if necessary - symptomatic therapy there is no specific antidote.

Storage conditions

In a dry, dark place at a temperature of no higher than 25 ° C.

Expiration

3 years

Active ingredient

Clotrimazole

Dosage form

powder for outdoor use

Glenmark Pharmaceuticals Ltd., India



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