Cerepro capsules 400 mg, 14 pcs. (Choline alfostserat)

Release form

Capsules

Packing

14 pcs.

Pharmacological action

Cerepro is a central anticholinergic stimulator containing 40.5% metabolically protected choline (metabolic protection promotes the release of choline in the brain).

When ingested, it is cleaved by enzymes into choline and glycerophosphate: choline is involved in the biosynthesis of acetylcholine - one of the main mediators of neural excitation, glycerophosphate is a precursor of phospholipids (phosphatidylcholine) of the neural membrane. Provides the synthesis of acetylcholine and phosphatidylcholine in neuronal membranes, improves blood flow and enhances metabolic processes in the central nervous system, activates the reticular formation.

Increases the linear blood flow velocity on the side of the traumatic brain injury, helps to normalize the spatio-temporal characteristics of spontaneous bioelectrical activity of the brain, and has a positive effect on cognitive and behavioral responses of patients with cerebrovascular diseases.

cerepro improves brain function, acting on the pathogenetic factors of involutional psycho-organic syndrome, it changes the phospholipid composition of the membranes of neurons and reduces cholinergic activity. Dose-dependently stimulates the release of acetylcholine by participating in the synthesis of phosphagidylcholine (membrane phospholipid), improves synaptic transmission, plasticity of neuronal membranes, and receptor function. It does not affect the reproductive cycle and does not have teratogenic and mutagenic effects.

Pharmacokinetics

Absorption - 88%), easily penetrates the blood-brain barrier (when taken orally, the concentration in the brain is 45%) of that in plasma). It is excreted mainly by the lungs, in the form of carbon dioxide (85%), as well as by the kidneys and through the intestines (15%).

Indications

acute and recovery periods of severe traumatic brain injury and ischemic stroke, recovery period of hemorrhagic stroke, occurring with focal hemispheric symptoms or symptoms of damage to the brain stem

psycho-organic syndrome against the background of degenerative and involutional changes in the brain

chronic cerebrovascular insufficiency

cognitive disorders (impaired mental function, memory, confusion, disorientation, decreased motivation, initiative and ability to concentrate) including with dementia and encephalopathy.

senile pseudomelancholy.

Contraindications

Hypersensitivity, pregnancy, breastfeeding.

Special instructions

If you experience nausea, you should reduce the dose after taking the drug.

Cerepro has no effect on the speed of psychomotor reactions.

Composition

1 capsule contains:

active substance:

400 mg glycerylphosphorylcholine hydrate (choline alfoscerate)

excipients:

glycerol (glycyrin),

purified water.

Capsule shell:

medical gelatin,

glycerol (glycerin),

methyl parahydroxybenzoate (methyl paraben),

propyl parahydroxybenzoate (propyl paraben),

dye sorbitol iron oxide, redbit srdp, drd

Dosage and administration of

In chronic conditions: 0.4 g inside (1 capsule) 3 times a day, preferably before meals.

Duration of treatment is 3-6 months.

Side effects

Allergic reactions, nausea (due to dopaminergic activation).

Storage conditions of

in a dry, dark place and out of the reach of children at a temperature of 25 ° C.

Expiration

2 years.

Deystvuyuschee substances

Choline alfostserat

Terms and conditions

prescription

dosage form

capsules

Veropharm, Russia



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