Chondroitin sulfate ampoules 100 mg, 10 pcs (chondroitin sulfate sulfate)

Release form

Lyophilisate for solution for intramuscular administration.

Packing

10 pcs.

Pharmacological action

Pharmacological action - chondrostimulating, chondroprotective.

Participates in the construction of the main substance of cartilage and bone tissue. It improves phosphorus-calcium metabolism in cartilage, inhibits enzymes that disrupt the structure and function of articular cartilage, and inhibits the degeneration of cartilage. It stimulates the synthesis of glucosaminoglycans, normalizes the metabolism of hyaline tissue, and promotes the regeneration of cartilage surfaces and articular bags. Prevents compression of connective tissue, increases the production of intraarticular fluid, increases the mobility of the affected joints. Slows down bone resorption, reduces calcium loss and accelerates bone tissue repair, inhibits the progression of osteoarthritis. It has an analgesic effect, reduces joint pain, pain at rest and when walking, the severity of inflammation, helps to reduce the need for NSAIDs.

After oral administration, it is rapidly absorbed from the digestive tract. Cmax is reached after 3-4 hours. It accumulates in the synovial fluid of the joints. Bioavailability is 13%. It is excreted by the kidneys.

Indications

Osteoarthrosis of the peripheral joints and spine.

Contraindications

Hypersensitivity to chondroitin sulfate, tendency to bleeding, thrombophlebitis, pregnancy, lactation period (breast-feeding should be discontinued during treatment).

Composition

1 ampoule of lyophilisate for the preparation of a solution for intramuscular administration contains: active substance: chondroitin sulfate 100 mg.

Dosage and administration of

Intramuscularly, 1 ml every other day. Before use, the contents of the ampoule are dissolved in 1 ml of water for injection. With good tolerance, the dose is increased to 2 ml, starting with the fourth injection. The course of treatment is 25 to 35 injections. Repeated courses - after 6 months.

The duration of repeated courses of treatment is determined by the doctor. To achieve a stable clinical effect, at least 25 injections of chondroitin sulfate are necessary, while the effect persists for many months after the end of the course of treatment. Repeated courses of treatment are indicated to prevent exacerbations.

Side effects

Allergic reactions, bleeding at the injection site.

Drug interaction

It is possible to enhance the action of indirect anticoagulants, antiplatelet agents, fibrinolytics, which requires more frequent monitoring of blood coagulation when used together.

Storage conditions

In a dry, dark place at a temperature of 18 ° C to 22 ° C.

Expiration

3 years.

Active ingredient

Chondroitin sulfate

Terms and conditions

prescription

Dosage form

injection for



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