Cinnarizine tablets 25 mg 50 pcs. (cinnarizine)

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Release form

Tablets. Buy Cinnarizine tablets 25 mg 50 pcs. (cinnarizine) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Release form

Tablets.

Packing

50 pcs.

Pharmacological action

Pharmaceutical group:

slow calcium channel blocker.

Pharmaceutical action:

Selective BMCC, reduces Ca2 + entry into cells and reduces their concentration in the plasma depot, reduces smooth muscle tone of arterioles, enhances the vasodilating effect of carbon dioxide.

Directly affecting the smooth muscles of blood vessels, reduces their response to nutrients (adrenaline, norepinephrine, dopamine, angiotensin, vasopressin). It has a vasodilating effect (especially in relation to cerebral vessels), without having a significant effect on blood pressure.

It exhibits moderate antihistamine activity, reduces the excitability of the vestibular apparatus, lowers the tone of the sympathetic nervous system.

Effective in patients with latent cerebrovascular insufficiency, initial atherosclerosis of the cerebral vessels and chronic diseases of the cerebral vessels with post-stroke focal symptoms.

In patients with impaired peripheral circulation, improves blood supply to organs and tissues (including the myocardium), enhances postischemic vasodilation.

Increases the elasticity of erythrocyte membranes, their ability to deform, reduces blood viscosity. Increases muscle resistance to hypoxia.

Pharmacokinetics:

TCmax after oral administration - 1-3 hours, communication with plasma proteins - 91%.

Completely metabolized in the liver (via dealkylation). T1 / 2 - 4 hours.

It is excreted in the form of metabolites: 1/3 - the kidneys and 2/3 - with feces.

Indications

Chronic cerebrovascular insufficiency (dizziness, tinnitus, headache, memory impairment, decreased attention span).

Vestibular disorders (including Meniere's disease, dizziness, tinnitus, nystagmus, nausea and vomiting of labyrinth origin).

Prevention of kinetosis (road sickness - sea and air sickness).

Migraine (attack prevention).

Disturbances of peripheral circulation (intermittent claudication, Raynaud's disease, diabetic angiopathy, thrombophlebitis, trophic disorders, including trophic and varicose ulcers).

Special instructions

Due to the antihistamine effect, cinnarizine can affect the result of anti-doping control of athletes (false-positive result), as well as neutralize positive reactions during skin diagnostic tests (treatment should be canceled 4 days before the study).

With prolonged use, a follow-up examination of liver, kidney and peripheral blood picture is recommended.

Breastfeeding is not recommended for women taking cinnarizine.

Patients with Parkinson's disease should be prescribed only in those cases where the benefits of its appointment exceed the possible risk of worsening.

During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require an increased concentration of attention and speed of psychomotor reactions.

Composition

Cinnarizine 25 mg.

Dosage and Administration

Inside, after meals.

In case of chronic cerebrovascular insufficiency - 25 mg 3 times a day, in drops - 8 drops 3 times a day or 1 capsule (75 mg) once a day.

In case of peripheral circulation disorder - 50-75 mg 3 times a day.

For the prevention of seasickness and airborne disease - 25 mg 30 minutes before the upcoming trip, if necessary, repeat the dose after 6 hours for children from 5 years - 1/2 dose for adults.

For vestibular disorders - 25 mg 3 times a day. For children, the dose is reduced by 2 times.

The maximum daily dose should not exceed 225 mg. With high sensitivity to the drug, treatment begins with 1/2 dose, increasing it gradually.

To achieve the optimal therapeutic effect, the drug should be taken continuously, for a long time - from several weeks to several months.

Side effects of the

From the nervous system: drowsiness, increased fatigue, headache, extrapyramidal disorders (tremor of the extremities and increased muscle tone, hypokinesia), depression.

From the digestive system: dry oral mucosa, epigastric pain, dyspepsia, cholestatic jaundice.

From the skin: increased sweating, lichen planus (extremely rare).

Allergic reactions: skin rash.

Other: decreased blood pressure, weight gain, lupus-like syndrome.

Drug Interactions

Enhances the effects of ethanol, sedatives, tricyclic antidepressants.

Overdose of

Symptoms: vomiting, drowsiness, tremor, excessive decrease in blood pressure, coma.

Treatment: there is no specific antidote, gastric lavage, activated charcoal, symptomatic therapy.

Actions yuschee substances

cinnarizine

Terms and conditions vacations from srdlk's vacation prescription

dosage form

tablets

Appointment

Children's doctor's appointment, Adult doctor's appointment

Pharma AD, Bulgaria



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