Citramon P tablets 10 pcs. (Acetylsalicylic acid, Caffeine, Paracetamol)

Latin name

Citramonum P

Release form

Tablets.

Packing

10 pcs

Pharmacological action

Combined drug.

Acetylsalicylic acid has an antipyretic and anti-inflammatory effect, relieves pain, especially caused by the inflammatory process, and also moderately inhibits platelet aggregation and thrombosis, improves microcirculation in the focus of inflammation.

Caffeine increases the reflex excitability of the spinal cord, stimulates the respiratory and vasomotor centers, dilates the blood vessels of the skeletal muscles, brain, heart, kidneys, reduces platelet aggregation, reduces drowsiness, and a feeling of tiredness. In this combination, caffeine in a small dose practically does not have a stimulating effect on the central nervous system, but it helps to regulate the tone of brain vessels.

Paracetamol has an analgesic, antipyretic and mild anti-inflammatory effect, due to its effect on the thermoregulation center in the hypothalamus and a mild ability to inhibit prostaglandin (Rd) synthesis in peripheral tissues.

Indications

Pain of mild to moderate severity (of various origins): headache, migraine, toothache, neuralgia, myalgia, arthralgia, algomenorrhea. Feverish syndrome: in acute respiratory diseases (ARI), flu.

Contraindications

gastric and duodenal ulcer in the acute phase

gastrointestinal bleeding (including a history)

severe liver and / or kidney dysfunctions

hemorrhagic sensitization of the drug srd.

Use during pregnancy and lactation

Contraindicated in pregnancy (I and III trimesters), during lactation.

Acetylsalicylic acid has a teratogenic effect when used in the first trimester of pregnancy leads to a malformation - splitting of the upper palate in the third trimester - to inhibition of labor activity (inhibition of prostaglandin synthesis), to closure of the arterial duct in the fetus, which causes pulmonary vascular hyperplasia and vascular hypertension pulmonary circulation.

Excreted in breast milk, which increases the risk of bleeding in a child due to impaired platelet function.

Composition

Active substances: acetylsalicylic acid - 240 mg, paracetamol - 180 mg, caffeine monohydrate or caffeine (caffeine anhydrous) - 30 mg.

Excipients: cocoa - 14 mg, citric acid - 5 mg, potato starch - 63 mg, low molecular weight povidone (medical polyvinylpyrrolidone low molecular weight) - 4 mg, talc - 9 mg, calcium stearate - 5 mg.

Dosage and Administration

Inside.

Assign to adults and children over 14 years of age 1-3 tablets. 2-3 times / day.

The maximum daily intake for adults is 6 tablets.

Side effects of

heartburn,

nausea,

epigastric pain,

erosive and ulcerative lesions of the gastrointestinal tract, (including complicated by bleeding),

increased bleeding,

urticaria.

Drug Interaction

The drug enhances the action of anticoagulants, the side effects of glucocorticoids and sulfonyl-urea derivatives.

Overdose

Symptoms (caused by acetylsalicylic acid): with mild intoxication - nausea, vomiting, gastralgia, dizziness, ringing in the ears severe intoxication - drowsiness, drowsiness, collapse, collapse, collapse, shortness of breath, anuria, bleeding.

Initially, central pulmonary hyperventilation results in respiratory alkalosis (shortness of breath, asphyxiation, cyanosis, and evaporation). As the intoxication intensifies, progressive respiratory paralysis and uncoupling of oxidative phosphorylation cause respiratory acidosis.

Treatment: constant control of acid-base balance and electrolyte balance depending on the state of metabolism - the introduction of sodium bicarbonate, sodium citrate or sodium lactate.

Increasing reserve alkalinity increases the excretion of acetylsalicylic acid by alkalinizing the urine.

Storage conditions

Keep out of the reach of children in the original packaging at a temperature not exceeding 25 ° C.

Expiration

5 years.

Deystvuyuschee substances

Atsetylsalytsylovaya acid, caffeine, paracetamol

Pharmacy terms

without a prescription

dosage form

dosage form

tablets

Pharmstandard-Leksredstva, Russia



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