Combiben rr for in / mouse. injection 2 ml ampoules 10 pcs. (Pyridoxine, thiamine, cyanocobalamin, lidocaine)

Latin name

Combilipen

Release form

Intravenous solution4rd4drd4drd4drd4drd4drd4 Solution for intramuscular injection



packaging 10 pcs

Pharmacological action

Combilipen - a combined multivitamin complex. The effect of the drug is determined by the properties of vitamins that make up its composition.

Benfotiamine is a fat-soluble form of thiamine (vitamin B1). Participates in a nerve impulse.

Pyridoxine hydrochloride (vitamin B6) - is involved in the metabolism of proteins, carbohydrates and fats, is necessary for normal blood formation, the functioning of the central and peripheral nervous system. It provides synaptic transmission, inhibition processes in the central nervous system, is involved in the transport of sphingosine, which is part of the nerve sheath, and is involved in the synthesis of catecholamines.

Cyanocobalamin (vitamin B12) - participates in the synthesis of nucleotides, is an important factor in the normal growth, hematopoiesis and development of epithelial cells is necessary for the metabolism of folic acid and the synthesis of myelin.

Indications

It is used in the complex treatment of the following neurological diseases: trigeminal neuralgia

facial neuritis

pain caused by diseases of the spine (intercostal neuralgia, lumbar ischialgia, lumbar syndrome, cervical, vertebral vertebral syndrome )

polyneuropathy of various etiologies (diabetic, alcoholic).

Contraindications

Hypersensitivity to the components of the drug Combilipen, severe and acute forms of decompensated heart failure. Pregnancy and lactation.

Special instructions

Combibipene contains benzyl alcohol. Do not prescribe to children because of the content of benzyl alcohol in the preparation.

Dosage and administration of

The drug is administered intramuscularly.

With severe manifestations of 2 ml daily for 5-7 days, then 2 ml 2-3 times a week for 2 weeks in mild cases, 2 ml 2-3 times a week for 7-10 days.

Duration is determined by the doctor individually, depending on the severity of the symptoms of the disease, but should not exceed two weeks. For maintenance therapy, the administration of oral forms of B vitamins is recommended.

Side effects

Allergic reactions (skin reactions in the form of pruritus, urticaria), increased sweating, tachycardia, acne, difficulty breathing, Quincke's edema, anaphylactic shock.

Drug interaction

Levodopa reduces the effect of therapeutic doses of vitamin B6. Vitamin B12 is incompatible with heavy metal salts. Ethanol dramatically reduces the absorption of thiamine. When taking the drug, it is not recommended to take multivitamin complexes that include B vitamins.

Overdose

Symptoms: increased side effects of the drug.

First Aid: symptomatic treatment.

Storage Conditions

In a dark place and out of the reach of children, at 2 to 8 ° C.

Shelf life

2 years.

Active ingredient

Pyridoxine, Thiamine, Cyanocobalamin, lidocaine

Terms and conditions

prescription

dosage form

injection

Indications

Indications

From radiculi neuritis, From trigeminal neuralgia, From sciatica

Pharmstandard-Ufavita, Russia



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