Cypromed eye drops 0.3%, 5 ml (Ciprofloxacin)
Special Price
$19.55
Regular Price
$23.00
In stock
SKU
newyork462328
Latin name pldfpffaf4fpfrdaflfpfrdfpfrdaf Buy Cypromed eye drops 0.3%, 5 ml (Ciprofloxacin) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Latin name pldfpffaf4fpfrdaflfpfrdfpfrdaf
Release form
eye drops.
Packaging
In a plastic dropper bottle, 5 ml drops. In a cardboard bundle 1 bottle.
Pharmacological action
An antibacterial drug from the group of fluoroquinolones for topical use in ophthalmology. It has a wide spectrum of antibacterial action, has a bactericidal effect. The mechanism of action is associated with the ability to inhibit the bacterial DNA gyrase enzyme, which leads to disruption of DNA replication and the synthesis of bacterial cellular proteins. Ciprofloxacin acts on both multiplying microorganisms and those at rest.
Active against gram-negative microorganisms: Esherichia coli, Salmonella spp., Shigella spp., Proteus spp. (indole-positive and indole-negative strains), Morganella morganii, Citrobacter spp., Klebsiella spp., Enterobacter spp., Vibrio spp., Campylobacter spp., Hafnia spp., Providencia stuartii, Haemophilus influenzae, Pasteurese multocaspp. , Gardnerella spp., Legionella pneumophila, Neisseria spp., Moraxella catarrhalis, Acinetobacter spp., Brucella spp., Chlamydia spp.
Gram-positive microorganisms are also sensitive to ciprofloxacin: Staphylococcus spp., Streptococcus pyogenes, Streptococcus agalactiae, Corynebacterium diphtheriae, Listeria monocitogenes.
The drug is low toxic.
Pharmacokinetics
Absorption
When applied topically, ciprofloxacin penetrates well into the tissues of the eye. After a single instillation, the concentration of ciprofloxacin in the moisture of the anterior chamber of the eye is reached after 10 minutes and is 100 μg / ml. Cmax in the moisture of the anterior chamber after 1 h is 190 μg / ml. After 2 hours, the concentration of the drug begins to decrease, while its antibacterial effect in the tissues of the cornea lasts up to 6 hours, in the moisture of the anterior chamber - up to 4 hours.
After instillation, systemic absorption of the drug is possible.
When treated for 7 days with 4 times / day in both eyes, the average concentration is less than 2 ng / ml.
Excretion of
When applied topically T1 / 2 from plasma is 4-5 hours. The drug is excreted by the kidneys unchanged - up to 50%, and in the form of metabolites - up to 10% through the intestines - about 15%.
Some of the drug excreted in breast milk.
Indications
Bacterial inflammatory diseases of the eye and its appendages: acute and subacute conjunctivitis
keratitis
anterior uveitis
blepharitis and other inflammatory diseases of the eyelids
dacryocystitis eye infections and treatment of it after treatment and prevention.
Contraindications
Hypersensitivity to the components of the drug or to other quinolones,
pregnancy,
period of breastfeeding,
children under 1 year old.
Use during pregnancy and lactation
Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.
Composition
1 ml eye drops contains: active substance: ciprofloxacin 3 mg,
excipients: excipients: benzalkonium chloride, sodium edetate, lactic acid, sodium chloride, sodium hydroxide, water d / and.
Dosage and administration
The drug is prescribed 1-2 drops in the conjunctival sac of the affected eye. The frequency of instillations depends on the severity of the inflammatory process.
In acute bacterial conjunctivitis, simple, Scaly and ulcerative blepharitis Cypromed is prescribed 4-8 times / day, depending on the severity of the inflammatory process. The course of treatment is from 5 to 14 days.
With keratitis, the drug is prescribed 1 drop at least 6 times / day. If there is a positive effect, the duration of therapy depends on the severity of the corneal lesion and is usually 2-4 weeks.
In case of damage to the cornea caused by Pseudomonas aeruginosa, Cypromed is prescribed 1 drop at least 8-12 times / day. The duration of therapy depends on the course of the disease and usually is about 2-3 weeks.
With anterior uveitis, the drug is prescribed 1 drop 8-12 times / day.
In acute dacryocystitis and canaliculitis, Tsipromed is prescribed 1 drop 6-12 times / day, in chronic cases - 4-8 times / day.
To prevent secondary infection in injuries of the eye and its appendages, Cypromed is prescribed 1 drop 4-8 times / day for 1-2 weeks.
For the prevention of inflammatory diseases after surgical procedures with perforation of the eyeball, Tsipromed is prescribed 1 drop 4-6 times / day throughout the postoperative period (usually from 5 days to 1 month).
Side effects
From the side of the organ of vision: immediately after instillation - a slight burning sensation for 1-2 minutes, itching, soreness, hyperemia of the mucous membrane of the eye is possible - allergic reactions, swelling of the eyelids, photophobia, lacrimation, sensation of a foreign body in the eye, an unpleasant aftertaste in the mouth immediately after instillation, decreased visual acuity, the appearance of white crystalline precipitate in patients with corneal ulcer, keratitis, keratopathy, spots or corneal infiltration, the development of superinfection.
Drug Interaction
Ciprofloxacin solution is incompatible with pH 3-4 drugs that are physically or chemically unstable.
Overdose
There are no specific symptoms when accidentally taking Cipromed inside. Possible: nausea, vomiting, diarrhea, headache, fainting, anxiety.
Treatment: standard emergency care, sufficient fluid intake, acid reaction to prevent crystalluria.
Storage conditions
The drug should be stored in a dark place at a temperature of no higher than 25 ° C. Do not freeze!
Expiration
2 years. After opening the vial, the Expiration is 1 month.
Deystvuyuschee substances
Ciprofloxacin
Sardlkp pharmacy leave terms for prescription
dosage form
dosage form
eye drops
Cypromed eye drops 0.3%, 5 ml (Ciprofloxacin) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Cypromed eye drops 0.3%, 5 ml - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
Release form
eye drops.
Packaging
In a plastic dropper bottle, 5 ml drops. In a cardboard bundle 1 bottle.
Pharmacological action
An antibacterial drug from the group of fluoroquinolones for topical use in ophthalmology. It has a wide spectrum of antibacterial action, has a bactericidal effect. The mechanism of action is associated with the ability to inhibit the bacterial DNA gyrase enzyme, which leads to disruption of DNA replication and the synthesis of bacterial cellular proteins. Ciprofloxacin acts on both multiplying microorganisms and those at rest.
Active against gram-negative microorganisms: Esherichia coli, Salmonella spp., Shigella spp., Proteus spp. (indole-positive and indole-negative strains), Morganella morganii, Citrobacter spp., Klebsiella spp., Enterobacter spp., Vibrio spp., Campylobacter spp., Hafnia spp., Providencia stuartii, Haemophilus influenzae, Pasteurese multocaspp. , Gardnerella spp., Legionella pneumophila, Neisseria spp., Moraxella catarrhalis, Acinetobacter spp., Brucella spp., Chlamydia spp.
Gram-positive microorganisms are also sensitive to ciprofloxacin: Staphylococcus spp., Streptococcus pyogenes, Streptococcus agalactiae, Corynebacterium diphtheriae, Listeria monocitogenes.
The drug is low toxic.
Pharmacokinetics
Absorption
When applied topically, ciprofloxacin penetrates well into the tissues of the eye. After a single instillation, the concentration of ciprofloxacin in the moisture of the anterior chamber of the eye is reached after 10 minutes and is 100 μg / ml. Cmax in the moisture of the anterior chamber after 1 h is 190 μg / ml. After 2 hours, the concentration of the drug begins to decrease, while its antibacterial effect in the tissues of the cornea lasts up to 6 hours, in the moisture of the anterior chamber - up to 4 hours.
After instillation, systemic absorption of the drug is possible.
When treated for 7 days with 4 times / day in both eyes, the average concentration is less than 2 ng / ml.
Excretion of
When applied topically T1 / 2 from plasma is 4-5 hours. The drug is excreted by the kidneys unchanged - up to 50%, and in the form of metabolites - up to 10% through the intestines - about 15%.
Some of the drug excreted in breast milk.
Indications
Bacterial inflammatory diseases of the eye and its appendages: acute and subacute conjunctivitis
keratitis
anterior uveitis
blepharitis and other inflammatory diseases of the eyelids
dacryocystitis eye infections and treatment of it after treatment and prevention.
Contraindications
Hypersensitivity to the components of the drug or to other quinolones,
pregnancy,
period of breastfeeding,
children under 1 year old.
Use during pregnancy and lactation
Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.
Composition
1 ml eye drops contains: active substance: ciprofloxacin 3 mg,
excipients: excipients: benzalkonium chloride, sodium edetate, lactic acid, sodium chloride, sodium hydroxide, water d / and.
Dosage and administration
The drug is prescribed 1-2 drops in the conjunctival sac of the affected eye. The frequency of instillations depends on the severity of the inflammatory process.
In acute bacterial conjunctivitis, simple, Scaly and ulcerative blepharitis Cypromed is prescribed 4-8 times / day, depending on the severity of the inflammatory process. The course of treatment is from 5 to 14 days.
With keratitis, the drug is prescribed 1 drop at least 6 times / day. If there is a positive effect, the duration of therapy depends on the severity of the corneal lesion and is usually 2-4 weeks.
In case of damage to the cornea caused by Pseudomonas aeruginosa, Cypromed is prescribed 1 drop at least 8-12 times / day. The duration of therapy depends on the course of the disease and usually is about 2-3 weeks.
With anterior uveitis, the drug is prescribed 1 drop 8-12 times / day.
In acute dacryocystitis and canaliculitis, Tsipromed is prescribed 1 drop 6-12 times / day, in chronic cases - 4-8 times / day.
To prevent secondary infection in injuries of the eye and its appendages, Cypromed is prescribed 1 drop 4-8 times / day for 1-2 weeks.
For the prevention of inflammatory diseases after surgical procedures with perforation of the eyeball, Tsipromed is prescribed 1 drop 4-6 times / day throughout the postoperative period (usually from 5 days to 1 month).
Side effects
From the side of the organ of vision: immediately after instillation - a slight burning sensation for 1-2 minutes, itching, soreness, hyperemia of the mucous membrane of the eye is possible - allergic reactions, swelling of the eyelids, photophobia, lacrimation, sensation of a foreign body in the eye, an unpleasant aftertaste in the mouth immediately after instillation, decreased visual acuity, the appearance of white crystalline precipitate in patients with corneal ulcer, keratitis, keratopathy, spots or corneal infiltration, the development of superinfection.
Drug Interaction
Ciprofloxacin solution is incompatible with pH 3-4 drugs that are physically or chemically unstable.
Overdose
There are no specific symptoms when accidentally taking Cipromed inside. Possible: nausea, vomiting, diarrhea, headache, fainting, anxiety.
Treatment: standard emergency care, sufficient fluid intake, acid reaction to prevent crystalluria.
Storage conditions
The drug should be stored in a dark place at a temperature of no higher than 25 ° C. Do not freeze!
Expiration
2 years. After opening the vial, the Expiration is 1 month.
Deystvuyuschee substances
Ciprofloxacin
Sardlkp pharmacy leave terms for prescription
dosage form
dosage form
eye drops
Cypromed eye drops 0.3%, 5 ml (Ciprofloxacin) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Cypromed eye drops 0.3%, 5 ml - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
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