Derinat spray 0.25% 10 ml (Dezoksyrybonukleat sodium)

Release form

Spray.

Packing

10 ml.

Pharmacological action

The drug activates cellular and humoral immunity. Optimizes specific reactions against fungal, viral and bacterial infections. The drug stimulates reparative and regenerative processes, normalizes the state of tissues and organs with dystrophy of vascular origin. Derinat promotes the healing of trophic ulcers of various etiologies. Derinat promotes the rapid healing of deep burns, significantly accelerating the dynamics of epithelization. With the restoration of ulcerative formations on the mucosa under the action of Derinat, scarless recovery occurs. The drug does not have teratogenic and carcinogenic effects.

Pharmacokinetics:

Derinat, when applied topically, is rapidly absorbed and distributed in organs and tissues with the participation of the endolymphatic transport pathway. In the phase of intensive drug intake into the blood, a redistribution occurs between plasma and blood cells, in parallel with metabolism and excretion. Derinat is metabolized in the body. It is excreted from the body (in the form of metabolites) partially with feces, and, to a greater extent, with urine according to biexponential dependence.

Contraindications

hypersensitivity to the components of the drug.

Use during pregnancy and lactation

The patient should be warned that a doctor should be consulted before using the drug during pregnancy and lactation. If necessary, the appointment of the drug during pregnancy should evaluate the expected benefits for the mother and the potential risk to the fetus.

Composition of

1 ml of solution contains sodium deoxyribonucleate - 2.5 mg, sodium chloride - 1.0 mg

Dosage and administration

Derinat in the form of a solution for external and local use is prescribed depending on the localization of the pathological process. The drug is prescribed for children from the first day of life and adults. For the prevention of acute respiratory viral infections, 2 drops are instilled into each nasal passage 2-4 times a day for 1-2 weeks. When symptoms of a respiratory disease appear, the drug is instilled 2-3 drops in each nasal passage every 1-1.5 hours during the first day, then 2-3 drops in each nasal passage 3-4 Duration of the course of therapy - from 5 days to 1 month . In inflammatory diseases of the nasal cavity and sinuses, the drug is instilled 3-5 drops in each nasal passage 4-6 times a day, the course duration is 7-15 days. In inflammatory diseases of the oral cavity, rinse the mouth with a solution of the drug 4-6 times a day (1 bottle for 2-3 rinses). The duration of the course of therapy is 5-10 days. In chronic inflammatory diseases, fungal, bacterial and other infections in gynecological practice - intravaginal administration of tampons with the drug or irrigation of the vagina and cervix of 5 ml per procedure 1-2 times a day for 10-14 days. With hemorrhoids, the drug is administered rectally with a microclyster of 15-40 ml. The duration of treatment is 4-10 days. In ophthalmic practice in severe inflammatory and dystrophic processes, Derinat is instilled in the eyes 1-2 drops 2-3 times a day for 14-45 days. With obliterating diseases of the lower extremities, in order to achieve a systemic effect, the drug is instilled 1-2 drops in each nasal passage 6 times a day, the duration of the course is up to 6 months. With postradiation necrosis of the skin and mucous membranes, with long-term non-healing wounds, burns, frostbite, trophic ulcers of various etiologies, gangrene on the affected areas is recommended to apply dressings (gauze in 2 layers) with the application of the drug 3-4 times a day or treat the affected surface with a drug from a spray of 10-40 ml 4-5 times a day. The course of treatment is 1-3 months.

Side effects of

No side effects were detected with topical and local use of the drug.

Storage conditions

The drug is recommended to be stored in a dry, dark place at temperatures from 4 ° to 18 ° С.

Terms and conditions

without prescription

lekarstvennaja form

spray nazaln y

Indications

Conjunctivitis, SARS, acute respiratory infections, the prevention of influenza, influenza

FZ Immunoleks, Russia



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