Dextrose (Dextrose)

Release form

Solution for infusion

Packing

Pack 250 ml

Pharmacological action

5% glucose solution is isotonic with respect to blood plasma and, when administered intravenously, replenishes the volume of circulating blood, when it is lost, it is a source of nutrient material, and also helps to remove poison from the body. Glucose provides a substrate replenishment of energy consumption. With intravenous injections, it activates metabolic processes, improves the antitoxic function of the liver, enhances the contractile activity of the myocardium, dilates blood vessels, and increases diuresis.

Pharmacokinetics

After administration, it is rapidly distributed in body tissues. It is excreted by the kidneys.

Contraindications

Hyperglycemia, diabetes mellitus, hyperhydration, postoperative disorders of glucose utilization, hyperosmolar coma, hyperlactacidemia.

Precautions - severe heart failure, pulmonary edema, oliguria, anuria, hyponatremia.

Use during pregnancy and lactation

The drug can be used according to indications.

Composition

1 l 5% solution contains:

Active glucose: 00 g (corresponding to glucose monohydrate 55.00 g)

Excipients: hydrochloric acid, water for injection.

Side effects

Fever, hypervolemia, the development of infection and thrombophlebitis at the injection site of Glucose, extravasation.

Drug Interactions

When used simultaneously with thiazide diuretics and furosemide, their ability to influence serum glucose levels should be considered. Insulin contributes to the release of glucose into peripheral tissues. A glucose solution reduces the toxic effect of pyrazinamide on the liver. The introduction of a large volume of glucose solution contributes to the development of hypokalemia, which increases the toxicity of simultaneously taken digitalis preparations.

Glucose is incompatible in solutions with aminophilin, soluble barbiturates, hydrocortisone, kanamycin, soluble sulfanilamides, cyanocobalamin.

Storage conditions

The drug should be stored out of the reach of children at a temperature not exceeding 2-8 ° C.

Term hodnosty

3 years

Deystvuyuschee substances

Dextrose

Pharmacy terms

Prescription

Dosage form

infusion solution

MEDPOLIMER, Russia



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