Dibazol ampoules 1%, 5 ml, 10 pcs. (Bendazol)

Latin name

DIBAZOL

Pharmacological action

Vasodilating agent has a hypotensive, vasodilating effect, stimulates the function of the spinal cord, has moderate immunostimulating activity. It has a direct antispasmodic effect on the smooth muscles of blood vessels and internal organs. Facilitates synaptic transmission in the spinal cord. Immunostimulating activity is associated with the regulation of the ratio of cGMP and cAMP concentrations in immune cells (increases the cGMP content), which leads to the proliferation of mature sensitized T and B lymphocytes, their secretion of mutual regulation factors, cooperative reaction, and activation of the final effector function of cells. It has a short (2-3 hours) and moderate hypotensive effect, is well tolerated. It causes expansion (short) of the cerebral vessels and is therefore especially indicated for forms of arterial hypertension due to chronic hypoxia of the brain due to local circulatory disorders (sclerosis of cerebral arteries).

Indications

Spasm of peripheral arteries: coronary spasm, arterial hypertension (including hypertensive crisis) spasm of smooth muscles of the internal organs: peptic ulcer of the stomach and duodenum, intestinal colic, renal and hepatic colitis, peripheral paralysis of the facial nerve, polyneuritis.

Special instructions

It is not recommended to appoint for long-term treatment of arterial hypertension, especially to elderly patients.

Composition

Solution for i / v and i / m administration 1 ml

bendazole 10 mg

Excipients: glycerol 108 mg, ethanol 95% 0.1 ml, hydrochloric acid 0.1 M 0.01 ml, water d / and up to 1 ml.

Dosage and administration

Hypertensive crisis - iv or iv 3-4 ml of 1% or 6-8 ml of 0.5% solution with significantly increased blood pressure without crisis symptoms - 2-4 ml of 1% or 4-8 ml of a 0.5% solution 2-3 times a day. Inside, 0.02-0.04 g 2-3 times a day for 3-4 weeks. For the treatment of diseases of the nervous system - 0. 005 g (adults) 5-10 times a day or every other day. After 3-4 weeks, the treatment is repeated. The following courses are carried out with a break of 1-2 months for children under 1 year old - 1 mg, 1-3 years old - 2 mg, 4-8 years old - 3 mg, 9-12 years old - 4 mg, older than 12 years old - 5 mg.

Side effects

Allergic reactions. When using high doses - a feeling of fever, sweating, dizziness, nausea, headache.

Drug Interactions

Prevents an increase in SPS associated with beta-blockers. Enhances the hypotensive effect of hypotensive and diuretic agents. Phentolamine enhances the hypotensive effect of bendazole.

Active ingredient

Bendazole

Dalchimpharm, Russia



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