Fenkarol tablets 50 mg 15 pcs. (Hyfenadyn)
Special Price
$23.80
Regular Price
$28.00
In stock
SKU
newyork502656
Pharmacological action
Fenkarol is a derivative of quinuclidylcarbinol, which reduces the effects of histamine on: organs and their systems. Fenkarol is a competitive blocker of H1 receptors. In addition, unlike the classical drugs of this group, it activates the enzyme diamine oxidase, which breaks down up to 30% of endogenous histamine. This explains the effectiveness of fencarol for patients resistant to other antihistamines. Fenkarol poorly penetrates the blood-brain barrier and has little effect on the processes of deamination of serotonin in the brain, weakly affects the activity of monoamine oxidase. The antihistamine properties of fencarol are associated with the presence of a cyclic quinuclidine nucleus in the structure and the distance between the diphenylcarbinol group and the nitrogen atom. Fencarol is superior to diphenhydramine in antihistamine activity and duration of action. Fenkarol reduces the toxic effect of histamine, eliminates or weakens its bronchoconstrictive effect and spasmodic effect on the smooth muscles of the intestine, possesses moderate antiserotonin and weak anticholinergic action, pronounced antipruritic and desensitizing properties. Fenkarol attenuates the hypotensive effect of histamine and its effect on capillary permeability. Fenkarol has no direct effect on cardiac activity and blood pressure. Fenkarol does not have a protective effect for aconitine arrhythmias. Unlike diphenhydramine (diphenhydramine) and diprazine (pipolfen), fenkarol does not have a depressing effect on the central nervous system, but with individual hypersensitivity, a slight sedation is possible. The drug is slightly lipophilic and, compared with diphenhydramine and other central nervous system inhibitory drugs with histamine-blocking agents, its content in brain tissues is low (less than 0.05%), which explains the absence of a depressing effect on the central nervous system.
Pharmacokinetics.
Fenkarol is rapidly absorbed from the gastrointestinal tract, and after 30 minutes the drug is found in the tissues of the body. The maximum concentration is reached in an hour.
Metabolites and the unchanged proportion of fencarol are mainly excreted in urine and bile within 48 hours. Buy Fenkarol tablets 50 mg 15 pcs. (Hyfenadyn) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Fenkarol is a derivative of quinuclidylcarbinol, which reduces the effects of histamine on: organs and their systems. Fenkarol is a competitive blocker of H1 receptors. In addition, unlike the classical drugs of this group, it activates the enzyme diamine oxidase, which breaks down up to 30% of endogenous histamine. This explains the effectiveness of fencarol for patients resistant to other antihistamines. Fenkarol poorly penetrates the blood-brain barrier and has little effect on the processes of deamination of serotonin in the brain, weakly affects the activity of monoamine oxidase. The antihistamine properties of fencarol are associated with the presence of a cyclic quinuclidine nucleus in the structure and the distance between the diphenylcarbinol group and the nitrogen atom. Fencarol is superior to diphenhydramine in antihistamine activity and duration of action. Fenkarol reduces the toxic effect of histamine, eliminates or weakens its bronchoconstrictive effect and spasmodic effect on the smooth muscles of the intestine, possesses moderate antiserotonin and weak anticholinergic action, pronounced antipruritic and desensitizing properties. Fenkarol attenuates the hypotensive effect of histamine and its effect on capillary permeability. Fenkarol has no direct effect on cardiac activity and blood pressure. Fenkarol does not have a protective effect for aconitine arrhythmias. Unlike diphenhydramine (diphenhydramine) and diprazine (pipolfen), fenkarol does not have a depressing effect on the central nervous system, but with individual hypersensitivity, a slight sedation is possible. The drug is slightly lipophilic and, compared with diphenhydramine and other central nervous system inhibitory drugs with histamine-blocking agents, its content in brain tissues is low (less than 0.05%), which explains the absence of a depressing effect on the central nervous system.
Pharmacokinetics.
Fenkarol is rapidly absorbed from the gastrointestinal tract, and after 30 minutes the drug is found in the tissues of the body. The maximum concentration is reached in an hour.
Metabolites and the unchanged proportion of fencarol are mainly excreted in urine and bile within 48 hours. Buy Fenkarol tablets 50 mg 15 pcs. (Hyfenadyn) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Pharmacological action
Fenkarol is a derivative of quinuclidylcarbinol, which reduces the effects of histamine on: organs and their systems. Fenkarol is a competitive blocker of H1 receptors. In addition, unlike the classical drugs of this group, it activates the enzyme diamine oxidase, which breaks down up to 30% of endogenous histamine. This explains the effectiveness of fencarol for patients resistant to other antihistamines. Fenkarol poorly penetrates the blood-brain barrier and has little effect on the processes of deamination of serotonin in the brain, weakly affects the activity of monoamine oxidase. The antihistamine properties of fencarol are associated with the presence of a cyclic quinuclidine nucleus in the structure and the distance between the diphenylcarbinol group and the nitrogen atom. Fencarol is superior to diphenhydramine in antihistamine activity and duration of action. Fenkarol reduces the toxic effect of histamine, eliminates or weakens its bronchoconstrictive effect and spasmodic effect on the smooth muscles of the intestine, possesses moderate antiserotonin and weak anticholinergic action, pronounced antipruritic and desensitizing properties. Fenkarol attenuates the hypotensive effect of histamine and its effect on capillary permeability. Fenkarol has no direct effect on cardiac activity and blood pressure. Fenkarol does not have a protective effect for aconitine arrhythmias. Unlike diphenhydramine (diphenhydramine) and diprazine (pipolfen), fenkarol does not have a depressing effect on the central nervous system, but with individual hypersensitivity, a slight sedation is possible. The drug is slightly lipophilic and, compared with diphenhydramine and other central nervous system inhibitory drugs with histamine-blocking agents, its content in brain tissues is low (less than 0.05%), which explains the absence of a depressing effect on the central nervous system.
Pharmacokinetics.
Fenkarol is rapidly absorbed from the gastrointestinal tract, and after 30 minutes the drug is found in the tissues of the body. The maximum concentration is reached in an hour.
Metabolites and the unchanged proportion of fencarol are mainly excreted in urine and bile within 48 hours.
Indications
Pollinosis, food and drug allergies, other allergic diseases, acute and chronic urticaria, edema (angioedema) Quincke, hay fever, allergic rhinopathy, dermatoses (eczema, psoriasis, neurodermatitis, and also non-allergic skin pruritus) with bronchospastic component.
Contraindications
1. Individual intolerance to the drug.
2. The first three months of pregnancy.
Use during pregnancy and lactation
Fenkarol is contraindicated in the first three months of pregnancy.
Composition
Quinuclidyl-3-diphenylcarbinol hydrochloride.
Pills in white.
Active ingredient - fenkarol. Each tablet contains 50 mg of active ingredient.
Excipients: sugar, potato starch, calcium stearate.
Dosage and administration of
Fenkarol is taken orally immediately after a meal. A single dose for adults - 25-50 mg 3-4 times a day. With pollinosis, a daily dosage of less than 75 mg is not effective. The maximum daily dose is 200 mg. The duration of treatment is 10-20 days.
Children under 3 years of age - 5 mg 2-3 times a day from 3 to 7 years old - 10 mg 2 times a day from 7 to 12 years old - 10-15 mg 2-3 times a day older than 12 years - 25 mg 2-3 times a day. The recommended daily dose can be taken in 4 divided doses. The duration of treatment is 10-15 days.
If the next dose was not taken on time, continue treatment at previously prescribed doses. If necessary, consult a doctor.
Side effects of
With hypersensitivity or an overdose of fencarol, mild dry mucous membranes of the oral cavity, dyspeptic symptoms, which usually disappear when the dose is reduced or the drug is withdrawn, may be observed. In people with diseases of the gastrointestinal tract, the possibility of side effects increases.
If side effects appear, especially such which are not indicated in the instructions, you must inform your doctor.
Overdose of
Daily dose up to 300 mg does not cause serious clinically adverse effects. Large doses can cause dry mucous membranes, headache, vomiting, epigastric pain and other dyspeptic symptoms.
Storage conditions
List B. Store in a dry, dark place, out of the reach of children. Do not take the drug after the expiration date.
Pharmacy leave conditions - over-the-counter.
Active ingredient
Hifenadine
Terms and conditions otpuska IZ
pharmacies without a prescription
The dosage form of
tablet
Appointment
Adult
Indications
Allergiya, from psoriasis, Neyrodermit, Эkzema, sensitization rhinitis Dermatosis, Urticaria, Pollinosis
Olainfarm, Latvia
Fenkarol tablets 50 mg 15 pcs. (Hyfenadyn) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Fenkarol tablets 50 mg 15 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
Fenkarol is a derivative of quinuclidylcarbinol, which reduces the effects of histamine on: organs and their systems. Fenkarol is a competitive blocker of H1 receptors. In addition, unlike the classical drugs of this group, it activates the enzyme diamine oxidase, which breaks down up to 30% of endogenous histamine. This explains the effectiveness of fencarol for patients resistant to other antihistamines. Fenkarol poorly penetrates the blood-brain barrier and has little effect on the processes of deamination of serotonin in the brain, weakly affects the activity of monoamine oxidase. The antihistamine properties of fencarol are associated with the presence of a cyclic quinuclidine nucleus in the structure and the distance between the diphenylcarbinol group and the nitrogen atom. Fencarol is superior to diphenhydramine in antihistamine activity and duration of action. Fenkarol reduces the toxic effect of histamine, eliminates or weakens its bronchoconstrictive effect and spasmodic effect on the smooth muscles of the intestine, possesses moderate antiserotonin and weak anticholinergic action, pronounced antipruritic and desensitizing properties. Fenkarol attenuates the hypotensive effect of histamine and its effect on capillary permeability. Fenkarol has no direct effect on cardiac activity and blood pressure. Fenkarol does not have a protective effect for aconitine arrhythmias. Unlike diphenhydramine (diphenhydramine) and diprazine (pipolfen), fenkarol does not have a depressing effect on the central nervous system, but with individual hypersensitivity, a slight sedation is possible. The drug is slightly lipophilic and, compared with diphenhydramine and other central nervous system inhibitory drugs with histamine-blocking agents, its content in brain tissues is low (less than 0.05%), which explains the absence of a depressing effect on the central nervous system.
Pharmacokinetics.
Fenkarol is rapidly absorbed from the gastrointestinal tract, and after 30 minutes the drug is found in the tissues of the body. The maximum concentration is reached in an hour.
Metabolites and the unchanged proportion of fencarol are mainly excreted in urine and bile within 48 hours.
Indications
Pollinosis, food and drug allergies, other allergic diseases, acute and chronic urticaria, edema (angioedema) Quincke, hay fever, allergic rhinopathy, dermatoses (eczema, psoriasis, neurodermatitis, and also non-allergic skin pruritus) with bronchospastic component.
Contraindications
1. Individual intolerance to the drug.
2. The first three months of pregnancy.
Use during pregnancy and lactation
Fenkarol is contraindicated in the first three months of pregnancy.
Composition
Quinuclidyl-3-diphenylcarbinol hydrochloride.
Pills in white.
Active ingredient - fenkarol. Each tablet contains 50 mg of active ingredient.
Excipients: sugar, potato starch, calcium stearate.
Dosage and administration of
Fenkarol is taken orally immediately after a meal. A single dose for adults - 25-50 mg 3-4 times a day. With pollinosis, a daily dosage of less than 75 mg is not effective. The maximum daily dose is 200 mg. The duration of treatment is 10-20 days.
Children under 3 years of age - 5 mg 2-3 times a day from 3 to 7 years old - 10 mg 2 times a day from 7 to 12 years old - 10-15 mg 2-3 times a day older than 12 years - 25 mg 2-3 times a day. The recommended daily dose can be taken in 4 divided doses. The duration of treatment is 10-15 days.
If the next dose was not taken on time, continue treatment at previously prescribed doses. If necessary, consult a doctor.
Side effects of
With hypersensitivity or an overdose of fencarol, mild dry mucous membranes of the oral cavity, dyspeptic symptoms, which usually disappear when the dose is reduced or the drug is withdrawn, may be observed. In people with diseases of the gastrointestinal tract, the possibility of side effects increases.
If side effects appear, especially such which are not indicated in the instructions, you must inform your doctor.
Overdose of
Daily dose up to 300 mg does not cause serious clinically adverse effects. Large doses can cause dry mucous membranes, headache, vomiting, epigastric pain and other dyspeptic symptoms.
Storage conditions
List B. Store in a dry, dark place, out of the reach of children. Do not take the drug after the expiration date.
Pharmacy leave conditions - over-the-counter.
Active ingredient
Hifenadine
Terms and conditions otpuska IZ
pharmacies without a prescription
The dosage form of
tablet
Appointment
Adult
Indications
Allergiya, from psoriasis, Neyrodermit, Эkzema, sensitization rhinitis Dermatosis, Urticaria, Pollinosis
Olainfarm, Latvia
Fenkarol tablets 50 mg 15 pcs. (Hyfenadyn) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Fenkarol tablets 50 mg 15 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
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