Gastrozole capsules 10 mg 14 pcs. (omeprazole)
Special Price
$18.70
Regular Price
$22.00
In stock
SKU
newyork979299
Pharmacological action
Inhibits H + K + ATPase (proton pump) in the parietal cells of the stomach and blocks the final stage of basal and stimulated secretion of hydrochloric acid.
After oral administration, acid secretion begins to decline within 1-2 hours. A 2-fold decrease in HCl biosynthesis is observed over a period of 17-24 hours. The pH of the gastric environment is maintained at 3 units. The maximum therapeutic effect is achieved on the 4th-5th day of treatment, and lasts 3-4 days after the end of the course.
The active component of Gastrozole is rapidly and almost completely absorbed in the digestive tract. The highest plasma concentration is recorded after) .5-3 hours after application.
Bioavailability level - dose-dependent, with a single dose it reaches 40%, and with a second dose - 70%. Omeprazole forms conjugates with acidic 1-glycoprotein and plasma albumin. Due to the high degree of lipophilicity, the substance freely enters the lining cells of the walls of the stomach. The active component has the ability to activate in their secretory tubules, where the medium has a pronounced acid reaction.
The process of biotransformation occurs in the liver. The resulting inactive metabolites are excreted in the urine (up to 80%) and bile. The half-life is from 30 to 60 minutes. A decrease in the functional activity of the kidneys increases bioavailability to 100%, but the half-life increases to 3 hours. Buy Gastrozole capsules 10 mg 14 pcs. (omeprazole) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Inhibits H + K + ATPase (proton pump) in the parietal cells of the stomach and blocks the final stage of basal and stimulated secretion of hydrochloric acid.
After oral administration, acid secretion begins to decline within 1-2 hours. A 2-fold decrease in HCl biosynthesis is observed over a period of 17-24 hours. The pH of the gastric environment is maintained at 3 units. The maximum therapeutic effect is achieved on the 4th-5th day of treatment, and lasts 3-4 days after the end of the course.
The active component of Gastrozole is rapidly and almost completely absorbed in the digestive tract. The highest plasma concentration is recorded after) .5-3 hours after application.
Bioavailability level - dose-dependent, with a single dose it reaches 40%, and with a second dose - 70%. Omeprazole forms conjugates with acidic 1-glycoprotein and plasma albumin. Due to the high degree of lipophilicity, the substance freely enters the lining cells of the walls of the stomach. The active component has the ability to activate in their secretory tubules, where the medium has a pronounced acid reaction.
The process of biotransformation occurs in the liver. The resulting inactive metabolites are excreted in the urine (up to 80%) and bile. The half-life is from 30 to 60 minutes. A decrease in the functional activity of the kidneys increases bioavailability to 100%, but the half-life increases to 3 hours. Buy Gastrozole capsules 10 mg 14 pcs. (omeprazole) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Pharmacological action
Inhibits H + K + ATPase (proton pump) in the parietal cells of the stomach and blocks the final stage of basal and stimulated secretion of hydrochloric acid.
After oral administration, acid secretion begins to decline within 1-2 hours. A 2-fold decrease in HCl biosynthesis is observed over a period of 17-24 hours. The pH of the gastric environment is maintained at 3 units. The maximum therapeutic effect is achieved on the 4th-5th day of treatment, and lasts 3-4 days after the end of the course.
The active component of Gastrozole is rapidly and almost completely absorbed in the digestive tract. The highest plasma concentration is recorded after) .5-3 hours after application.
Bioavailability level - dose-dependent, with a single dose it reaches 40%, and with a second dose - 70%. Omeprazole forms conjugates with acidic 1-glycoprotein and plasma albumin. Due to the high degree of lipophilicity, the substance freely enters the lining cells of the walls of the stomach. The active component has the ability to activate in their secretory tubules, where the medium has a pronounced acid reaction.
The process of biotransformation occurs in the liver. The resulting inactive metabolites are excreted in the urine (up to 80%) and bile. The half-life is from 30 to 60 minutes. A decrease in the functional activity of the kidneys increases bioavailability to 100%, but the half-life increases to 3 hours.
Indications
treatment of peptic ulcer of the stomach and duodenum
prevention of relapse of peptic ulcer of the stomach and duodenum
reflux esophagitis
hypersecretory syndrome, gastrointestinal syndrome, gastrointestinal syndrome, Helicobacter pylori eradication in infected patients with gastric and duodenal ulcer (as part of combination therapy)
Contraindications
Hypersensitivity to the drug Gastrozole.
Special instructions
Before starting treatment, it is necessary to exclude the presence of a malignant process (especially with gastric ulcer), because Gastrozole may mask symptoms and delay the correct diagnosis.
Taking the drug at the same time as food does not affect its effectiveness.
Use in cases of impaired liver function
Use with caution in patients with hepatic impairment.
Use in cases of impaired renal function
Use with caution in patients with renal failure.
Composition of
1 capsule contains 10 mg omeprazole
Dosage and administration
Inside, in the morning, on an empty stomach, without chewing and washing down with a small amount of liquid.
With exacerbation of peptic ulcer of the stomach and duodenum - 20 mg once a day, if necessary, the dose can be increased to 40 mg once a day. The duration of treatment is from 4 (in patients with a duodenal ulcer) to 8 weeks (in patients with a stomach ulcer). With poor healing of the ulcer, it is recommended to prescribe the drug for another 4 weeks.
For the prevention of relapse of gastric ulcer and duodenal ulcer - 20-40 mg (if necessary) 1 time per day.
With reflux esophagitis - 20–40 mg once a day for 4–12 weeks.
With Zollinger-Ellison syndrome, the dose is set individually. The recommended starting dose is 60 mg once daily. A dose exceeding 80 mg / day should be divided into 2 doses (every 12 hours), a dose of more than 120 mg - into 3 doses.
For the prevention of acid aspiration - 40 mg in the evening before surgery and 40 mg 1–4 hours before the procedure.
Treatment of erosive and ulcerative lesions, caused by taking NSAIDs - 20 mg 1 time per day for 4 weeks, if necessary, treatment can be continued for another 4 weeks. For the prevention of relapse, maintenance therapy at a dose of 20 mg is recommended.
With peptic ulcer associated with Helicobacter pylori there are several combination therapy regimens (triple or double):
20 mg gastrozole, 1 g amoxicillin and 500 mg clarithromycin 2 times a day for 1 week
20 mg gastrozole, 250 mg of clarithromycin and 400 mg of metronidazole 2 times a day for 1 week
40 mg of gastrozole, 500 mg of amoxicillin and 400 mg of metronidazole 3 times a day for 1 week
20-40 mg of gastrozole 1 time per day, 500 mg of clarithromycin 3 times per day and 0, 75–1 g of amoxicillin 2 times a day for 2 weeks
40 mg of gastrozole and 750 mg of amoxicillin 2 times a day for 2 weeks.
For patients with impaired liver function, the maximum daily dose is 20 mg.
Side effects
From the nervous system and sensory organs: dizziness, headache, agitation, depression.
From the cardiovascular system and blood (hematopoiesis, hemostasis): leukemia, thrombocytopenia, agranulocytosis.
From the digestive tract: dry mouth, nausea, vomiting, abdominal pain, flatulence, diarrhea or constipation, increased activity of hepatic transaminases.
From the musculoskeletal system: arthralgia, myalgia.
From the skin: photosensitivity, alopecia, erythema multiforme.
Allergic reactions: urticaria, skin rash.
Overdose
Symptoms: confusion, blurred vision, drowsiness, dry mouth, headache, nausea, tachycardia, arrhythmia.
Treatment: symptomatic treatment. Hemodialysis is not effective enough.
Active ingredient
Omeprazole
Terms and conditions otpuska from
pharmacies Without a prescription
lekarstvennaja form
kapsul
Gastrozole capsules 10 mg 14 pcs. (omeprazole) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Gastrozole capsules 10 mg 14 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
Inhibits H + K + ATPase (proton pump) in the parietal cells of the stomach and blocks the final stage of basal and stimulated secretion of hydrochloric acid.
After oral administration, acid secretion begins to decline within 1-2 hours. A 2-fold decrease in HCl biosynthesis is observed over a period of 17-24 hours. The pH of the gastric environment is maintained at 3 units. The maximum therapeutic effect is achieved on the 4th-5th day of treatment, and lasts 3-4 days after the end of the course.
The active component of Gastrozole is rapidly and almost completely absorbed in the digestive tract. The highest plasma concentration is recorded after) .5-3 hours after application.
Bioavailability level - dose-dependent, with a single dose it reaches 40%, and with a second dose - 70%. Omeprazole forms conjugates with acidic 1-glycoprotein and plasma albumin. Due to the high degree of lipophilicity, the substance freely enters the lining cells of the walls of the stomach. The active component has the ability to activate in their secretory tubules, where the medium has a pronounced acid reaction.
The process of biotransformation occurs in the liver. The resulting inactive metabolites are excreted in the urine (up to 80%) and bile. The half-life is from 30 to 60 minutes. A decrease in the functional activity of the kidneys increases bioavailability to 100%, but the half-life increases to 3 hours.
Indications
treatment of peptic ulcer of the stomach and duodenum
prevention of relapse of peptic ulcer of the stomach and duodenum
reflux esophagitis
hypersecretory syndrome, gastrointestinal syndrome, gastrointestinal syndrome, Helicobacter pylori eradication in infected patients with gastric and duodenal ulcer (as part of combination therapy)
Contraindications
Hypersensitivity to the drug Gastrozole.
Special instructions
Before starting treatment, it is necessary to exclude the presence of a malignant process (especially with gastric ulcer), because Gastrozole may mask symptoms and delay the correct diagnosis.
Taking the drug at the same time as food does not affect its effectiveness.
Use in cases of impaired liver function
Use with caution in patients with hepatic impairment.
Use in cases of impaired renal function
Use with caution in patients with renal failure.
Composition of
1 capsule contains 10 mg omeprazole
Dosage and administration
Inside, in the morning, on an empty stomach, without chewing and washing down with a small amount of liquid.
With exacerbation of peptic ulcer of the stomach and duodenum - 20 mg once a day, if necessary, the dose can be increased to 40 mg once a day. The duration of treatment is from 4 (in patients with a duodenal ulcer) to 8 weeks (in patients with a stomach ulcer). With poor healing of the ulcer, it is recommended to prescribe the drug for another 4 weeks.
For the prevention of relapse of gastric ulcer and duodenal ulcer - 20-40 mg (if necessary) 1 time per day.
With reflux esophagitis - 20–40 mg once a day for 4–12 weeks.
With Zollinger-Ellison syndrome, the dose is set individually. The recommended starting dose is 60 mg once daily. A dose exceeding 80 mg / day should be divided into 2 doses (every 12 hours), a dose of more than 120 mg - into 3 doses.
For the prevention of acid aspiration - 40 mg in the evening before surgery and 40 mg 1–4 hours before the procedure.
Treatment of erosive and ulcerative lesions, caused by taking NSAIDs - 20 mg 1 time per day for 4 weeks, if necessary, treatment can be continued for another 4 weeks. For the prevention of relapse, maintenance therapy at a dose of 20 mg is recommended.
With peptic ulcer associated with Helicobacter pylori there are several combination therapy regimens (triple or double):
20 mg gastrozole, 1 g amoxicillin and 500 mg clarithromycin 2 times a day for 1 week
20 mg gastrozole, 250 mg of clarithromycin and 400 mg of metronidazole 2 times a day for 1 week
40 mg of gastrozole, 500 mg of amoxicillin and 400 mg of metronidazole 3 times a day for 1 week
20-40 mg of gastrozole 1 time per day, 500 mg of clarithromycin 3 times per day and 0, 75–1 g of amoxicillin 2 times a day for 2 weeks
40 mg of gastrozole and 750 mg of amoxicillin 2 times a day for 2 weeks.
For patients with impaired liver function, the maximum daily dose is 20 mg.
Side effects
From the nervous system and sensory organs: dizziness, headache, agitation, depression.
From the cardiovascular system and blood (hematopoiesis, hemostasis): leukemia, thrombocytopenia, agranulocytosis.
From the digestive tract: dry mouth, nausea, vomiting, abdominal pain, flatulence, diarrhea or constipation, increased activity of hepatic transaminases.
From the musculoskeletal system: arthralgia, myalgia.
From the skin: photosensitivity, alopecia, erythema multiforme.
Allergic reactions: urticaria, skin rash.
Overdose
Symptoms: confusion, blurred vision, drowsiness, dry mouth, headache, nausea, tachycardia, arrhythmia.
Treatment: symptomatic treatment. Hemodialysis is not effective enough.
Active ingredient
Omeprazole
Terms and conditions otpuska from
pharmacies Without a prescription
lekarstvennaja form
kapsul
Gastrozole capsules 10 mg 14 pcs. (omeprazole) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Gastrozole capsules 10 mg 14 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
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