Gliatilin capsules 400 mg, 14 pcs. (Choline alfostserat)

packaging 14 pcs

Pharmacological action

Gliatilin is a central cholinomimetic with a primary effect on the central nervous system. It has a neuroprotective effect. Choline is released in the brain. Choline is involved in the biosynthesis of acetylcholine (one of the main mediators of nervous excitation). Alfoscerate is biotransformed to glycerophosphate, which is a precursor of phospholipids.

Gliatilin improves transmission of nerve impulses in cholinergic neurons, positively affects the plasticity of neuronal membranes and receptor function. Increases cerebral blood flow, enhances metabolic processes and activates the structure of the reticular formation of the brain, and also restores consciousness in traumatic brain damage.

It has a preventive and corrective effect on factors of the involutive psycho-organic syndrome, such as a change in the phospholipid composition of neuronal membranes and a decrease in cholinergic activity.

Experimental studies have shown that gliatilin stimulates dose-dependent secretion of acetylcholine under physiological conditions of nerve impulse transmission.

Increases the synthesis of acetylcholine and positively affects the transmission of nerve impulses, and glycerophosphate is involved in the synthesis of phosphatidylcholine (membrane phospholipid), resulting in improved membrane elasticity and receptor function.

Contraindications

Hypersensitivity to the components of the drug.

Use during pregnancy and lactation

The drug is not recommended for use during pregnancy and during lactation (breastfeeding).

In experimental studies, no embryotoxic and teratogenic effects of the drug, as well as effects on reproductive functions, were revealed.

Dosage and Administration

Inside, before meals.

In case of chronic cerebrovascular insufficiency, changes in the emotional and behavioral sphere and multi-infarction dementia: inside - 400 mg (1 capsule) 3 times a day.

Duration of therapy is 3–6 months.

Side effects

Nausea (as a result of dopaminergic activation), in this case, the dose of the drug should be reduced. Allergic reactions are possible.

Drug Interaction

Drug interaction Gliatilin has not been established.

Overdose

Symptoms: nausea. At occurrence of this symptom it is recommended to reduce the dose of the drug.

Storage conditions

At a temperature not exceeding 25 ° C.

The Expiration of

is 3 years.

dosage form

dosage form

capsules



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