Glutargin alkocline 1g sachets 2 pcs. (arginine glutamate)

Release form

Powder for solution for oral administration.

Packing

2 pcs.

Pharmacological action

Pharmaceutical group: Hypoammonia medication.

Pharmaceutical action: Glutargin alkocline is a combination of arginine and glutamic acid, which play an important role in ensuring biochemical processes of neutralization and excretion of the highly toxic metabolite of nitrogenous metabolism - ammonia. It has a hepatoprotective effect, having antioxidant, antihypoxic and membrane stabilizing activity, positively affects the energy supply processes in hepatocytes.

With alcohol intoxication, Glutargin alkocline stimulates the utilization of alcohol in the monooxygenase system of the liver, prevents the inhibition of the key enzyme of ethanol utilization - alcohol dehydrogenase accelerates the inactivation and elimination of toxic products of ethanol metabolism as a result of an increase in the formation and oxidation of succinic acid and reduces the inhibitory effect of alcohol on the central nervous system due to the neurotransmitter properties of exciting glutamic acid.

Glutargin alkocline has no embryotoxic, gonadotoxic and mutagenic effects, does not cause allergic and immunotoxic reactions.

Indications

- prevention of intoxication and the hepatotoxic effect of alcohol

- treatment of acute alcohol intoxication of mild to moderate severity, as well as as part of the complex treatment of post-toxicosis disorders after severe acute alcohol poisoning.

Contraindications

- hypersensitivity to the components of the

drug - children under 18 years of age

- pregnancy and lactation

- phenylketonuria, since the drug contains aspartame

Caution

- febrile - severe srdlpr nitrogen excretion) renal function (creatinine clearance 30 ml / min)

Special instructions

When prescribing to patients with impaired endocrine glands, it should be borne in mind that the drug may slightly increase the secretion of insulin and growth hormones, that does not require correction of drug therapy in patients with diabetes mellitus and / or acromegaly

Effect of the drug on the ability to drive vehicles

The drug does not affect the ability to drive vehicles

Composition

Active ingredient: arginine glutamate (in terms of 100% substance) 1.0 g.

Excipient: glycine 0.50 g, mannitol (E421) 0.79 G, citric acid (without water) 0, 60 g, aspartame (E951) 0.06 g, Lemon flavoring 0.05 g

Dosage and administration of

The drug is prescribed for adults inside, regardless of food intake, will we first dissolve the packet in? -? glasses of water. To prevent intoxication and the hepatotoxic effect of alcohol, 2 packets (2 g of arginine glutamate) are prescribed 1 to 2 hours before drinking or 1 packet (1 g of arginine glutamate) 1 hour before drinking and 1 packet (1 g of arginine glutamate) for 0, 5 hours after drinking alcohol. For the treatment of acute alcohol intoxication of mild and moderate severity, 1 packet is prescribed 4 times a day with an interval of 1-2.5 hours, in the next 2-3 days - 1 packet 2 times a day. With severe alcohol poisoning, after a course of intravenous administration of the drug Glutargin Alcocline, 1 packet is prescribed 2 times a day for 20 days as part of complex therapy.

Side effects

Rarely there may be feelings of mild discomfort in the epigastric region and nausea immediately after using the drug, which pass on its own.

Storage conditions

Store in its original packaging, at a temperature not exceeding 25 ° C. Keep out of the reach of children.

Expiration

2 years.

Form of Treatment

simply entails dlya accepts vnutry



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