Hyalur solution for intraarticular injection. 15 mg / ml 2 ml syringe 1 pc. (sodium hyaluronate)

Release form

Intra-articular solution

Packaging

Syringe 2 ml.

Pharmacological action

Solution for intra-articular administration HYALUROM - 1.5% sodium hyaluronate solution in 2 ml disposable syringes is a sterile, viscoelastic sodium hyaluronate solution. Sodium hyaluronate is obtained by fermentation. Sodium hyaluronate HYALUROM is a polysaccharide identical to human, consists of repeating disaccharide units of N-acetylglycosamine and sodium glucuronate, with a molecular weight exceeding 2,400,000 Da. Sodium hyaluronate is present everywhere in the human body and is present in high concentrations in tissues such as the vitreous, synovial fluid, umbilical cord and dermis. In synovial fluid, sodium hyaluronate acts as a lubricant and shock absorber, which contributes to normal movement without pain. In case of a disease like arthritis, the viscoelasticity of the synovial fluid decreases, so that the mechanical load on the joint increases significantly and the destruction of the articular cartilage is increased, it is manifested by limitation and pain when moving in the joints. The lubricating and cushioning effect of this drug alleviates pain and improves joint mobility during intraarticular use. These effects last more than 6 months after one course of treatment.

Indications

HYALUROM solution is used as a viscoelastic supplement to replace synovial fluid for pain caused by degenerative diseases of the synovial joints, such as osteoarthritis or osteoarthritis. In its action, the HYALUROM drug serves as a lubricant and mechanical support for a diseased joint.

HYALUROM solution is injected into the joints of a person: for pain and limited mobility caused by degenerative-dystrophic and traumatic changes in the knee,

hip and other synovial joints for temporary replacement and replenishment of

synovial fluid in the treatment of patients who lead an active lifestyle and regularly load the affected joint.

Contraindications

individual intolerance (including a history of hypersensitivity) of the solution components HYALUROM

presence of infected wounds, abrasions in the joint area

infectious diseases of the joints

known systemic disorders of blood coagulation. HYALUROM may contain traces of bacterial proteins and is contraindicated in patients with appropriate hypersensitivity.

Composition

1 syringe contains:

Active substances: sodium hyaluronate, sodium chloride, water for injection.

Dosage and administration

Injections of HYALUROM are made by specialist doctors. The HYALUROM solution is intended for intraarticular use only. Do not use intravenously. The introduction of sodium hyaluronate is carried out at room temperature. The volume injected depends on the size of the joint, but does not exceed 2 ml in the knee joint and other large joints, or 1 ml for small joints. The doctor is responsible for determining the applicable volume and must ensure that the joint is not overloaded. The HYALUROM solution is injected into the joint cavity once a week for 3 consecutive weeks. Simultaneous treatment of several joints is possible. The repeated treatment cycle cannot be carried out earlier than after 6 months, for the same joint. Before using the HYALUROM drug, the accumulation of fluid in the joint should be removed by suction with a syringe. The HYALUROM solution is available in the form of a pre-filled syringe, the contents of which do not need to be diluted. The drug is sterile and must be used immediately after opening the package. The drug is intended for single use only. HYALUROM must be carefully inserted into the joint cavity, carefully observing the administration schedule. The introduction is an aseptic procedure, so take appropriate precautions. The finished syringe is removed from the sterile case, the cap is removed, after which a sterile needle is put on, which is fixed by a small rotation. Before introduction it is necessary to remove air from the syringe.

Side effects

Sodium hyaluronate has excellent tolerance. Perhaps the occurrence of local secondary phenomena, such as pain, a feeling of warmth, redness and swelling, can be observed on the joint, into which the drug is injected (applying ice to the joint within five to ten minutes will remove all such phenomena). Very rarely, allergic reactions can be observed. With intra-articular administration, there are minimal risks associated with infection and bleeding.

active substance

Hyaluronate Sodium

Terms of delivery from

pharmacies Prescription

dosage form

infusion solution

K.O. Rompharm Company S.R.L., Romania



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