Lysoretic tablets 10 mg + 12.5 mg, 28 pcs. (lisinopril, Hydrohlorotyazyd)
Special Price
$23.80
Regular Price
$28.00
In stock
SKU
newyork471243
Release form
Tablets. Buy Lysoretic tablets 10 mg + 12.5 mg, 28 pcs. (lisinopril, Hydrohlorotyazyd) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Tablets. Buy Lysoretic tablets 10 mg + 12.5 mg, 28 pcs. (lisinopril, Hydrohlorotyazyd) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Release form
Tablets.
Packing
28 pcs. packaged.
Pharmacological action
Lysoretic has an antihypertensive, diuretic effect.
Contraindications
- anuria
- severe renal failure (CC less than 30 ml / min)
- angioedema (including a history of the use of ACE inhibitors)
- hemodialysis using high-flow membranes
- hypercalcemia
- hyponatremia
- porphyria
- precoma, hepatic coma
- diabetes mellitus - severe spl period srd (efficacy and safety not established)
- hypersensitivity to the components of the drug
- hypersensitivity to other ACE inhibitors and sulfanilamide derivatives.
Precautions: aortic stenosis / hypertrophic cardiomyopathy, bilateral renal artery stenosis, stenosis of a single kidney artery with progressive azotemia, condition after kidney transplantation, renal failure (CC more than 30 ml / min), primary hyperaldosteronism, arterial hypotension,
Use during pregnancy and lactation
Use of lysoretics during pregnancy is contraindicated. When pregnancy is established, the drug should be discontinued as soon as possible. Reception of inhibitors in the II and III trimester of pregnancy has an adverse effect on the fetus (a pronounced decrease in blood pressure, renal failure, hyperkalemia, skull hypoplasia, intrauterine death are possible). There are no data on the negative effects of Lysoretik on the fetus if used during the first trimester. It is recommended to monitor newborns and infants who underwent intrauterine exposure to ACE inhibitors to timely detect a pronounced decrease in blood pressure, oliguria, hyperkalemia. For the period of treatment with the drug, it is necessary to cancel breastfeeding.
Special instructions
The most pronounced decrease in blood pressure occurs with a decrease in BCC caused by diuretic therapy, a decrease in the amount of salt in food, dialysis, diarrhea, or vomiting. In patients with chronic heart failure with simultaneous renal failure or without it, the development of symptomatic hypotension is possible. It is more often detected in patients with severe forms of heart failure, as a result of the use of large doses of diuretics, hyponatremia, or impaired renal function. In such patients, treatment should begin under the strict supervision of a physician. Similar rules should be followed when prescribing to patients with coronary artery disease, cerebrovascular insufficiency, in which a sharp decrease in blood pressure can lead to myocardial infarction or stroke.
Influence on the ability to drive vehicles and operate machinery:
During the treatment period, patients should refrain from driving vehicles and engaging in potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions, as dizziness is possible, especially at the beginning of the course of treatment.
Composition
1 tab. contains lisinopril 10 mg, hydrochlorothiazide 12.5 mg.
Excipients: calcium hydrogen phosphate, mannitol, corn starch, pregelatinized starch, iron oxide red, iron oxide yellow, magnesium stearate, purified water.
Dosage and administration of
Take orally 1 tablet. Lysoretica 10 mg + 12.5 mg 1 time / day. If necessary, the dose can be increased to 1 table. Lysoretica 20 mg + 12.5 mg 1 time per day.
Doses for renal failure:
In patients with CC more than 30 and less than 80 ml / min, the drug can be used only after titration of a dose of individual components of the drug. The recommended initial dose of lisinopril for uncomplicated renal failure is 5-10 mg.
Side effects of
From the cardiovascular system: marked decrease in blood pressure, chest pain rarely - orthostatic hypotension, tachycardia, bradycardia, onset of symptoms of heart failure, impaired AV conduction, myocardial infarction.
From the digestive tract: nausea, vomiting, abdominal pain, dry mouth, diarrhea, dyspepsia, anorexia, taste change, pancreatitis, hepatitis (hepatocellular and cholestatic), jaundice.
From the skin: urticaria, increased sweating, photosensitivity, skin itching, hair loss.
From the side of the nervous system: lability of mood, impaired concentration of attention, paresthesia, increased fatigue, drowsiness, convulsive twitching of the muscles of the limbs and lips rarely - asthenic syndrome, confusion.
From the respiratory system: dyspnea, bronchospasm, apnea.
From the hemopoietic system: leukopenia, thrombocytopenia, neutropenia, agranulocytosis, anemia (decreased hemoglobin, hematocrit, erythrocytopenia).
Allergic reactions: angioedema of the face, limbs, lips, tongue, epiglottis and / or larynx, skin rashes, itching, fever, vasculitis, positive reactions to antinuclear antibodies, increased ESR, eosinophilia.
From the genitourinary system: uremia, oliguria / anuria, impaired renal function, acute renal failure, decreased potency.
Laboratory indicators: hyperkalemia and / or hypokalemia, hyponatremia, hypomagnesemia, hypochloraemia, hypercalcemia, hyperuricemia, hyperglycemia, increased levels of urea and creatinine in blood plasma, hyperbilirubinemia, hypercholesterolemia, hypertemia, high blood pressure a history of kidney disease, diabetes mellitus and renovascular hypertension.
Other: dry cough, arthralgia, arthritis, myalgia, fever, impaired fetal development, exacerbation of gout.
Drug interaction
When used simultaneously with potassium-sparing diuretics (spironolactone, triamteren, amiloride), potassium preparations, and salt substitutes containing potassium, the risk of hyperkalemia increases, especially in patients with impaired renal function.
With simultaneous use with vasodilators, barbiturates, phenothiazines, tricyclic antidepressants, ethanol, the hypotensive effect is enhanced.
With the simultaneous use of NSAIDs (indomethacin and others), estrogen decreases the antihypertensive effect of lisinopril.
With simultaneous use with lithium preparations, a slowdown in the excretion of lithium from the body is noted (increased cardiotoxic and neurotoxic effects of lithium).
With simultaneous use with antacids and colestramine, absorption from the gastrointestinal tract is reduced.
The drug enhances the neurotoxicity of salicylates.
The drug reduces the effects of oral hypoglycemic agents, norepinephrine, epinephrine and anti-gout agents.
The drug enhances the effects (including side) of cardiac glycosides, the action of peripheral muscle relaxants.
The drug reduces the excretion of quinidine.
Reduces the effectiveness of oral contraceptives.
Overdose
Symptoms: marked decrease in blood pressure.
Treatment: artificial vomiting and / or gastric lavage, symptomatic therapy aimed at correcting dehydration and water-salt balance disorders. Isotonic solution should be administered for hypotension. Control of urea, creatinine and electrolytes in serum, as well as diuresis is required.
Storage Conditions
In a dark place at a temperature not exceeding 15 ° C.
Shelf life
2 years.
Deystvuyushtee substance
Lisinopril, Gidrohlorotiazid
Dosage form
tablets
Possible product names Lg. X28
LYSORETIC 0.01 + 0.0125 N28 TABLE P / O
LYSORETIC 10MG. + 12.5MG. No. 28 TAB. P / O
LYSORETIC TAB 10MG + 12.5 MG No. 28
Lysoretic table. 10mg + 12.5mg N28 India
Lysoretic tablets 10 mg + 12.5 mg, 28 pcs. (lisinopril, Hydrohlorotyazyd) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Lysoretic tablets 10 mg + 12.5 mg, 28 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
Tablets.
Packing
28 pcs. packaged.
Pharmacological action
Lysoretic has an antihypertensive, diuretic effect.
Contraindications
- anuria
- severe renal failure (CC less than 30 ml / min)
- angioedema (including a history of the use of ACE inhibitors)
- hemodialysis using high-flow membranes
- hypercalcemia
- hyponatremia
- porphyria
- precoma, hepatic coma
- diabetes mellitus - severe spl period srd (efficacy and safety not established)
- hypersensitivity to the components of the drug
- hypersensitivity to other ACE inhibitors and sulfanilamide derivatives.
Precautions: aortic stenosis / hypertrophic cardiomyopathy, bilateral renal artery stenosis, stenosis of a single kidney artery with progressive azotemia, condition after kidney transplantation, renal failure (CC more than 30 ml / min), primary hyperaldosteronism, arterial hypotension,
Use during pregnancy and lactation
Use of lysoretics during pregnancy is contraindicated. When pregnancy is established, the drug should be discontinued as soon as possible. Reception of inhibitors in the II and III trimester of pregnancy has an adverse effect on the fetus (a pronounced decrease in blood pressure, renal failure, hyperkalemia, skull hypoplasia, intrauterine death are possible). There are no data on the negative effects of Lysoretik on the fetus if used during the first trimester. It is recommended to monitor newborns and infants who underwent intrauterine exposure to ACE inhibitors to timely detect a pronounced decrease in blood pressure, oliguria, hyperkalemia. For the period of treatment with the drug, it is necessary to cancel breastfeeding.
Special instructions
The most pronounced decrease in blood pressure occurs with a decrease in BCC caused by diuretic therapy, a decrease in the amount of salt in food, dialysis, diarrhea, or vomiting. In patients with chronic heart failure with simultaneous renal failure or without it, the development of symptomatic hypotension is possible. It is more often detected in patients with severe forms of heart failure, as a result of the use of large doses of diuretics, hyponatremia, or impaired renal function. In such patients, treatment should begin under the strict supervision of a physician. Similar rules should be followed when prescribing to patients with coronary artery disease, cerebrovascular insufficiency, in which a sharp decrease in blood pressure can lead to myocardial infarction or stroke.
Influence on the ability to drive vehicles and operate machinery:
During the treatment period, patients should refrain from driving vehicles and engaging in potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions, as dizziness is possible, especially at the beginning of the course of treatment.
Composition
1 tab. contains lisinopril 10 mg, hydrochlorothiazide 12.5 mg.
Excipients: calcium hydrogen phosphate, mannitol, corn starch, pregelatinized starch, iron oxide red, iron oxide yellow, magnesium stearate, purified water.
Dosage and administration of
Take orally 1 tablet. Lysoretica 10 mg + 12.5 mg 1 time / day. If necessary, the dose can be increased to 1 table. Lysoretica 20 mg + 12.5 mg 1 time per day.
Doses for renal failure:
In patients with CC more than 30 and less than 80 ml / min, the drug can be used only after titration of a dose of individual components of the drug. The recommended initial dose of lisinopril for uncomplicated renal failure is 5-10 mg.
Side effects of
From the cardiovascular system: marked decrease in blood pressure, chest pain rarely - orthostatic hypotension, tachycardia, bradycardia, onset of symptoms of heart failure, impaired AV conduction, myocardial infarction.
From the digestive tract: nausea, vomiting, abdominal pain, dry mouth, diarrhea, dyspepsia, anorexia, taste change, pancreatitis, hepatitis (hepatocellular and cholestatic), jaundice.
From the skin: urticaria, increased sweating, photosensitivity, skin itching, hair loss.
From the side of the nervous system: lability of mood, impaired concentration of attention, paresthesia, increased fatigue, drowsiness, convulsive twitching of the muscles of the limbs and lips rarely - asthenic syndrome, confusion.
From the respiratory system: dyspnea, bronchospasm, apnea.
From the hemopoietic system: leukopenia, thrombocytopenia, neutropenia, agranulocytosis, anemia (decreased hemoglobin, hematocrit, erythrocytopenia).
Allergic reactions: angioedema of the face, limbs, lips, tongue, epiglottis and / or larynx, skin rashes, itching, fever, vasculitis, positive reactions to antinuclear antibodies, increased ESR, eosinophilia.
From the genitourinary system: uremia, oliguria / anuria, impaired renal function, acute renal failure, decreased potency.
Laboratory indicators: hyperkalemia and / or hypokalemia, hyponatremia, hypomagnesemia, hypochloraemia, hypercalcemia, hyperuricemia, hyperglycemia, increased levels of urea and creatinine in blood plasma, hyperbilirubinemia, hypercholesterolemia, hypertemia, high blood pressure a history of kidney disease, diabetes mellitus and renovascular hypertension.
Other: dry cough, arthralgia, arthritis, myalgia, fever, impaired fetal development, exacerbation of gout.
Drug interaction
When used simultaneously with potassium-sparing diuretics (spironolactone, triamteren, amiloride), potassium preparations, and salt substitutes containing potassium, the risk of hyperkalemia increases, especially in patients with impaired renal function.
With simultaneous use with vasodilators, barbiturates, phenothiazines, tricyclic antidepressants, ethanol, the hypotensive effect is enhanced.
With the simultaneous use of NSAIDs (indomethacin and others), estrogen decreases the antihypertensive effect of lisinopril.
With simultaneous use with lithium preparations, a slowdown in the excretion of lithium from the body is noted (increased cardiotoxic and neurotoxic effects of lithium).
With simultaneous use with antacids and colestramine, absorption from the gastrointestinal tract is reduced.
The drug enhances the neurotoxicity of salicylates.
The drug reduces the effects of oral hypoglycemic agents, norepinephrine, epinephrine and anti-gout agents.
The drug enhances the effects (including side) of cardiac glycosides, the action of peripheral muscle relaxants.
The drug reduces the excretion of quinidine.
Reduces the effectiveness of oral contraceptives.
Overdose
Symptoms: marked decrease in blood pressure.
Treatment: artificial vomiting and / or gastric lavage, symptomatic therapy aimed at correcting dehydration and water-salt balance disorders. Isotonic solution should be administered for hypotension. Control of urea, creatinine and electrolytes in serum, as well as diuresis is required.
Storage Conditions
In a dark place at a temperature not exceeding 15 ° C.
Shelf life
2 years.
Deystvuyushtee substance
Lisinopril, Gidrohlorotiazid
Dosage form
tablets
Possible product names Lg. X28
LYSORETIC 0.01 + 0.0125 N28 TABLE P / O
LYSORETIC 10MG. + 12.5MG. No. 28 TAB. P / O
LYSORETIC TAB 10MG + 12.5 MG No. 28
Lysoretic table. 10mg + 12.5mg N28 India
Lysoretic tablets 10 mg + 12.5 mg, 28 pcs. (lisinopril, Hydrohlorotyazyd) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Lysoretic tablets 10 mg + 12.5 mg, 28 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
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