Magnerot tablets 500 mg 50 pcs. (magnesium orotate)

Latin name

SERUM AGAINST OREFI NEREFRENEFRENEFRENEFRENEFRENEFRENEFRENEFRENEFRENEFRENEFRENEFENEFIREFEREDENEFRENEFREDERENEFREDERENEREDERENT

Magnerot

Release form

Tablets.

Packaging

Per pack 50 pcs.

Pharmacological action

Magnerot - a preparation of magnesium. Magnesium is a macrocell, it is necessary for providing many energy processes, it is involved in the metabolism of proteins, fats, carbohydrates and nucleic acids. Magnesium takes part in the process of neuromuscular excitation, inhibiting neuromuscular transmission. Of particular interest is magnesium as a natural physiological calcium antagonist.

Magnesium controls the normal functioning of myocardial cells, is involved in the regulation of myocardial contractile function. In stressful situations, an increased amount of free ionized magnesium is excreted, and therefore an additional amount of magnesium contributes to an increase in resistance to stress.

Magnesium deficiency leads to neuromuscular disorders (motor and sensory hyperactivity, convulsions, paresthesia), mental changes (depression, confusion and hallucinations), cardiovascular diseases (ventricular extrasystole, tachycardia, and increased sensitivity to cardiac glycosides).

Magnesium deficiency during pregnancy increases the likelihood of toxicosis and premature birth. Salts of orotic acid are involved in the metabolism. In addition, salts of orotic acid are necessary for the fixation of magnesium on ATP in the cell and the manifestation of its action.

Pharmacokinetics

Absorbed approximately 35–40% of the dose taken. Hypomagnesemia stimulates the absorption of magnesium ions. The presence of orotic acid salts improves the absorption of magnesium. Magnesium is excreted by the kidneys, excretion decreases with a deficiency of magnesium and increases with its excess.

Indications

myocardial infarction

angina pectoris

chronic heart failure

cardiac arrhythmias caused by magnesium deficiency

spastic conditions - pain and muscle spasms (including angiospasm)

atherosclerosis lipid arteriosclerosis lipid arteriosclerosis erythematosis

Contraindications

hypersensitivity to the components of the drug

impaired renal function

urolithiasis

predisposition to the formation of calcium-magnesium-ammonium-phosphate stones

lactobacillus malignancy 18 .

Use during pregnancy and lactation

It is possible to use the drug during pregnancy and lactation (breastfeeding) according to indications, since during these periods the need for magnesium increases significantly. If its content is not balanced, then this can lead to serious complications, including miscarriage.

Use of the drug during pregnancy and lactation is possible if the potential benefit to the mother outweighs the potential risk to the fetus and baby.

Ingredients

Active ingredient mgdrgp colloidal silicon dioxide - 2.5 mg carmellose sodium - 10 mg MCC - 67.5 mg corn starch - 22.5 mg povidone K30 - 30 mg lactose monohydrate - 50 mg sodium cyclamate - 1.5 mg talc - 18.75 mg magnesium stearate - 1.63 mg

Dosage and administration

Inside, before meals, with a small amount of liquid.

Assign 2 tablets 3 times a day for 7 days, then 1 tablet 2-3 times a day daily. The duration of the course is at least 4-6 weeks. If necessary, Magnerot® can be used for a long time.

For night cramps of the calf muscles, it is recommended to take 2-3 tablets in the evening.

Side effects

From the gastrointestinal tract: unstable stool and diarrhea (when taking high doses), which usually go away on their own with a lower dose.

Allergic reactions.

If any of these side effects worsen or any other side effects that are not listed in the instructions appear, you should inform your doctor.

Overdose

Symptoms: decreased blood pressure, nausea, vomiting, depression, slowing reflexes, respiratory depression, coma, cardiac arrest, anuric syndrome.

Treatment: rehydration, forced diuresis. Renal insufficiency requires hemodialysis or peritoneal dialysis.

Storage conditions

At a temperature not exceeding 25 ° C.

term life

5 Chron

Dispensing conditions from

pharmacies Without a prescription

dosage form

dosage form

tablets

Crest Pharma Lek, Germany



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