metoclopramide ampoules 5 mg / ml, 2 ml, 10 pcs. (metoclopramide)
Special Price
$18.70
Regular Price
$22.00
In stock
SKU
newyork473397
Latin name
Metoclopramide Buy metoclopramide ampoules 5 mg / ml, 2 ml, 10 pcs. (metoclopramide) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Metoclopramide Buy metoclopramide ampoules 5 mg / ml, 2 ml, 10 pcs. (metoclopramide) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Latin name
Metoclopramide
Release form
Injection solution
Packing
10 ampoules of 2 ml.
Pharmacological action
Metoclopramide - an antiemetic, helps reduce nausea, hiccups stimulate gastrointestinal motility. The antiemetic effect due to blockade of dopamine D2 receptors and an increase in the threshold of the trigger zone chemoreceptors is a blocker of serotonin receptors. It is believed that metoclopramide inhibits the relaxation of smooth muscle of the stomach caused by dopamine, thereby enhancing cholinergic reactions of the smooth muscles of the gastrointestinal tract. Helps to accelerate the emptying of the stomach by preventing relaxation of the body of the stomach and increasing the activity of the antrum and upper small intestine. Reduces the reflux of contents into the esophagus by increasing the pressure of the sphincter of the esophagus at rest and increases the clearance of acid from the esophagus due to an increase in the amplitude of its peristaltic contractions.
Metoclopramide stimulates prolactin secretion and causes a transient increase in circulating aldosterone, which may be accompanied by short-term fluid retention.
Indications
vomiting, nausea, hiccups of various origins (in some cases it can be effective for vomiting caused by radiation therapy or taking cytostatics)
atony and hypotension of the stomach and intestines (in particular, postoperative)
biliary tract reflex dyskinesia Esophagitis
flatulence
functional pyloric stenosis.
as part of the complex treatment of exacerbations of gastric and duodenal ulcer
is used to enhance peristalsis during X-ray contrast studies of the gastrointestinal tract
as a means, facilitating duodenal sounding (to accelerate the emptying of the stomach and the movement of food through the small intestine).
Contraindications
bleeding from the gastrointestinal tract
stenosis of the pylorus
mechanical intestinal obstruction
perforation of the stomach wall or bowel
pheochromocytoma
epilepsy
glaucoma
extrapyramidal disorders
Parkinson's disease
prolaktinozavisimye tumor
vomiting during therapy or antipsychotic drugs overdose in patients
breast cancer bronchial asthma in patients with hypersensitivity to
sulfites pregnancy (I trimester), lact period
anions early childhood (for children under 2 years of age - the use of metoclopramide in the form of any dosage forms is contraindicated for children under 6 years of age, parenteral administration is contraindicated)
hypersensitivity to metoclopramide or any of the components of the drug.
Do not prescribe after gastrointestinal surgery (such as pyloroplasty or intestinal anastomosis), since vigorous muscle contractions interfere with healing.
If you are hypersensitive to metoclopramide or other components of the drug, be sure to consult your doctor before taking it.
Precautions: bronchial asthma, arterial hypertension, Parkinson's disease, renal and / or liver failure, advanced age (over 65 years), childhood (increased risk of developing dyskinetic syndrome).
Pregnancy and lactation
Contraindicated in pregnancy.
When used during lactation (breastfeeding), it should be borne in mind that metoclopramide passes into breast milk.
In experimental studies, no adverse effects of metoclopramide on the fetus were found.
Composition of
1 ml of the solution contains:
Active ingredient: metoclopramide hydrochloride - 5 mg
Excipients: disodium hydrochloric acid and sodium disodium hydrochloric acid for injection.
Method of use and doses
Injection solution is administered intravenously or intramuscularly to adults in a dose of 10–20 mg (maximum daily dose is 60 mg) for children over 6 years old - 5 mg 1 –3 times a day for children aged 2 to 6 years, the daily dose is 0.5–1 mg / kg body weight, the frequency of administration is 1-3 times.
For the prevention and treatment of nausea and vomiting due to cytostatics or radiation therapy, the drug is administered intravenously at a dose of 2 mg / kg body weight 30 minutes before the use of cytostatics or irradiation, if necessary, the administration is repeated after 2-3 hours.
Before radiological examination, adults are administered iv 10–20 mg 5–15 minutes before start of research.
Patients with clinically severe hepatic-renal failure are initially prescribed a dose 2 times lower than the usual dose, the next dose depends on the patient's individual response to metoclopramide.
Side effects of the
From the digestive system: at the beginning of treatment, constipation is possible, diarrhea is rare - dry mouth.
From the side of the central nervous system: at the beginning of treatment, a feeling of tiredness, drowsiness, dizziness, headache, depression, akathisia are possible. Extrapyramidal symptoms may occur in children and young adults (even after a single use of metoclopramide): facial muscle spasm, hyperkinesis, spasmodic torticollis (usually go away immediately after stopping metoclopramide). With prolonged use, more often in elderly patients, the phenomena of parkinsonism, dyskinesia are possible.
From the hematopoietic system: agranulocytosis is possible at the beginning of treatment.
From the endocrine system: rarely, with prolonged use in high doses - galactorrhea, gynecomastia, menstrual irregularities.
Allergic reactions: rarely - skin rash.
ЛРкарствРнноРвзаимодРйствимbr>
При одноврРмРнном примРнРнии с антихолинРргичРскими срРдствами возможно взаимноРослаблРниРэффРктов.
При одноврРмРнном примРнРнии с нРйролРптиками (особРнно фРнотиазинового ряда и производн х бутирофРнона) пов шаРтся риск возникновРния экстрапирамидн х рРакций.
При одноврРмРнном примРнРнии усиливаРтся абсорбция ацРтилсалициловой кислот , парацРтамола, этанола.
МРтоклопрамид при в/в ввРдРнии пов шаРт скорость абсорбции диазРпама и пов шаРт Рго максимальную концРнтрацию в плазмРкрови.
При одноврРмРнном примРнРнии с мРдлРнно растворяющРйся лРкарствРнной формой дигоксина возможно умРньшРниРконцРнтрации дигоксина в с вороткРкрови на 1/3. При одноврРмРнном примРнРнии с дигоксином в жидкой лРкарствРнной формРили в видРб строрастворимой лРкарствРнной форм взаимодРйствия нРотмРчРно.
При одноврРмРнном примРнРнии с зопиклоном ускоряРтся абсорбциязопиклона с кабРрголином - возможно умРньшРниРэффРктивности кабРрголина с кРтопрофРном - умРньшаРтся биодоступность кРтопрофРна.
ВслРдствиРантагонизма в отношРнии допаминов х рРцРпторов мРтоклопрамид можРт умРньшать противопаркинсоничРскоРдРйствиРлРводоп , при этом возможно пов шРниРбиодоступности лРводоп вслРдствиРускорРния РРэвакуации из жРлудка под влияниРм мРтоклопрамида. РРзультат взаимодРйствия нРоднозначн .
При одноврРмРнном примРнРнии с мРксилРтином ускоряРтся абсорбция мРксилРтина с мРфлохином - пов шаРтся скорость абсорбции мРфлохина и Рго концРнтрация в плазмРкрови, при этом возможно умРньшРниРРго побочн х эффРктов.
При одноврРмРнном примРнРнии с морфином ускоряРтся абсорбция морфина при приРмРвнутрь и усиливаРтся Рго сРдативноРдРйствиР.
При одноврРмРнном примРнРнии с нитрофурантоином умРньшаРтся абсорбция нитрофурантоина.
При примРнРнии мРтоклопрамида нРпосрРдствРнно пРрРд ввРдРниРм пропофола или тиопРнтала можРт потрРбоваться умРньшРниРих индукционн х доз.
У пациРнтов, получающих мРтоклопрамид, усиливаются и пролонгируются эффРкт суксамРтония хлорида.
При одноврРмРнном примРнРнии с толтРродином умРньшаРтся эффРктивность мРтоклопрамида с флувоксамином - описан случай развития экстрапирамидн х нарушРний с флуоксРтином - имРРтся риск развития экстрапирамидн х нарушРний с циклоспорином - пов шаРтся абсорбция циклоспорина и увРличиваРтся Рго концРнтрация в плазмРкрови.
Storage Conditions
In a dry, dark place at a temperature not exceeding 25 ° C.
shelf life
3 years
Deystvuyushtee substance
Metoclopramide
dosage form
injection
Possible product names
metoclopramide ampoules 5 mg / ml, 2 ml, 10 pcs.
Novosibkhimpharm, Russia
metoclopramide ampoules 5 mg / ml, 2 ml, 10 pcs. (metoclopramide) florida in pharmacy online. Cheap price, instruction, side effects, dosage. metoclopramide ampoules 5 mg / ml, 2 ml, 10 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
Metoclopramide
Release form
Injection solution
Packing
10 ampoules of 2 ml.
Pharmacological action
Metoclopramide - an antiemetic, helps reduce nausea, hiccups stimulate gastrointestinal motility. The antiemetic effect due to blockade of dopamine D2 receptors and an increase in the threshold of the trigger zone chemoreceptors is a blocker of serotonin receptors. It is believed that metoclopramide inhibits the relaxation of smooth muscle of the stomach caused by dopamine, thereby enhancing cholinergic reactions of the smooth muscles of the gastrointestinal tract. Helps to accelerate the emptying of the stomach by preventing relaxation of the body of the stomach and increasing the activity of the antrum and upper small intestine. Reduces the reflux of contents into the esophagus by increasing the pressure of the sphincter of the esophagus at rest and increases the clearance of acid from the esophagus due to an increase in the amplitude of its peristaltic contractions.
Metoclopramide stimulates prolactin secretion and causes a transient increase in circulating aldosterone, which may be accompanied by short-term fluid retention.
Indications
vomiting, nausea, hiccups of various origins (in some cases it can be effective for vomiting caused by radiation therapy or taking cytostatics)
atony and hypotension of the stomach and intestines (in particular, postoperative)
biliary tract reflex dyskinesia Esophagitis
flatulence
functional pyloric stenosis.
as part of the complex treatment of exacerbations of gastric and duodenal ulcer
is used to enhance peristalsis during X-ray contrast studies of the gastrointestinal tract
as a means, facilitating duodenal sounding (to accelerate the emptying of the stomach and the movement of food through the small intestine).
Contraindications
bleeding from the gastrointestinal tract
stenosis of the pylorus
mechanical intestinal obstruction
perforation of the stomach wall or bowel
pheochromocytoma
epilepsy
glaucoma
extrapyramidal disorders
Parkinson's disease
prolaktinozavisimye tumor
vomiting during therapy or antipsychotic drugs overdose in patients
breast cancer bronchial asthma in patients with hypersensitivity to
sulfites pregnancy (I trimester), lact period
anions early childhood (for children under 2 years of age - the use of metoclopramide in the form of any dosage forms is contraindicated for children under 6 years of age, parenteral administration is contraindicated)
hypersensitivity to metoclopramide or any of the components of the drug.
Do not prescribe after gastrointestinal surgery (such as pyloroplasty or intestinal anastomosis), since vigorous muscle contractions interfere with healing.
If you are hypersensitive to metoclopramide or other components of the drug, be sure to consult your doctor before taking it.
Precautions: bronchial asthma, arterial hypertension, Parkinson's disease, renal and / or liver failure, advanced age (over 65 years), childhood (increased risk of developing dyskinetic syndrome).
Pregnancy and lactation
Contraindicated in pregnancy.
When used during lactation (breastfeeding), it should be borne in mind that metoclopramide passes into breast milk.
In experimental studies, no adverse effects of metoclopramide on the fetus were found.
Composition of
1 ml of the solution contains:
Active ingredient: metoclopramide hydrochloride - 5 mg
Excipients: disodium hydrochloric acid and sodium disodium hydrochloric acid for injection.
Method of use and doses
Injection solution is administered intravenously or intramuscularly to adults in a dose of 10–20 mg (maximum daily dose is 60 mg) for children over 6 years old - 5 mg 1 –3 times a day for children aged 2 to 6 years, the daily dose is 0.5–1 mg / kg body weight, the frequency of administration is 1-3 times.
For the prevention and treatment of nausea and vomiting due to cytostatics or radiation therapy, the drug is administered intravenously at a dose of 2 mg / kg body weight 30 minutes before the use of cytostatics or irradiation, if necessary, the administration is repeated after 2-3 hours.
Before radiological examination, adults are administered iv 10–20 mg 5–15 minutes before start of research.
Patients with clinically severe hepatic-renal failure are initially prescribed a dose 2 times lower than the usual dose, the next dose depends on the patient's individual response to metoclopramide.
Side effects of the
From the digestive system: at the beginning of treatment, constipation is possible, diarrhea is rare - dry mouth.
From the side of the central nervous system: at the beginning of treatment, a feeling of tiredness, drowsiness, dizziness, headache, depression, akathisia are possible. Extrapyramidal symptoms may occur in children and young adults (even after a single use of metoclopramide): facial muscle spasm, hyperkinesis, spasmodic torticollis (usually go away immediately after stopping metoclopramide). With prolonged use, more often in elderly patients, the phenomena of parkinsonism, dyskinesia are possible.
From the hematopoietic system: agranulocytosis is possible at the beginning of treatment.
From the endocrine system: rarely, with prolonged use in high doses - galactorrhea, gynecomastia, menstrual irregularities.
Allergic reactions: rarely - skin rash.
ЛРкарствРнноРвзаимодРйствимbr>
При одноврРмРнном примРнРнии с антихолинРргичРскими срРдствами возможно взаимноРослаблРниРэффРктов.
При одноврРмРнном примРнРнии с нРйролРптиками (особРнно фРнотиазинового ряда и производн х бутирофРнона) пов шаРтся риск возникновРния экстрапирамидн х рРакций.
При одноврРмРнном примРнРнии усиливаРтся абсорбция ацРтилсалициловой кислот , парацРтамола, этанола.
МРтоклопрамид при в/в ввРдРнии пов шаРт скорость абсорбции диазРпама и пов шаРт Рго максимальную концРнтрацию в плазмРкрови.
При одноврРмРнном примРнРнии с мРдлРнно растворяющРйся лРкарствРнной формой дигоксина возможно умРньшРниРконцРнтрации дигоксина в с вороткРкрови на 1/3. При одноврРмРнном примРнРнии с дигоксином в жидкой лРкарствРнной формРили в видРб строрастворимой лРкарствРнной форм взаимодРйствия нРотмРчРно.
При одноврРмРнном примРнРнии с зопиклоном ускоряРтся абсорбциязопиклона с кабРрголином - возможно умРньшРниРэффРктивности кабРрголина с кРтопрофРном - умРньшаРтся биодоступность кРтопрофРна.
ВслРдствиРантагонизма в отношРнии допаминов х рРцРпторов мРтоклопрамид можРт умРньшать противопаркинсоничРскоРдРйствиРлРводоп , при этом возможно пов шРниРбиодоступности лРводоп вслРдствиРускорРния РРэвакуации из жРлудка под влияниРм мРтоклопрамида. РРзультат взаимодРйствия нРоднозначн .
При одноврРмРнном примРнРнии с мРксилРтином ускоряРтся абсорбция мРксилРтина с мРфлохином - пов шаРтся скорость абсорбции мРфлохина и Рго концРнтрация в плазмРкрови, при этом возможно умРньшРниРРго побочн х эффРктов.
При одноврРмРнном примРнРнии с морфином ускоряРтся абсорбция морфина при приРмРвнутрь и усиливаРтся Рго сРдативноРдРйствиР.
При одноврРмРнном примРнРнии с нитрофурантоином умРньшаРтся абсорбция нитрофурантоина.
При примРнРнии мРтоклопрамида нРпосрРдствРнно пРрРд ввРдРниРм пропофола или тиопРнтала можРт потрРбоваться умРньшРниРих индукционн х доз.
У пациРнтов, получающих мРтоклопрамид, усиливаются и пролонгируются эффРкт суксамРтония хлорида.
При одноврРмРнном примРнРнии с толтРродином умРньшаРтся эффРктивность мРтоклопрамида с флувоксамином - описан случай развития экстрапирамидн х нарушРний с флуоксРтином - имРРтся риск развития экстрапирамидн х нарушРний с циклоспорином - пов шаРтся абсорбция циклоспорина и увРличиваРтся Рго концРнтрация в плазмРкрови.
Storage Conditions
In a dry, dark place at a temperature not exceeding 25 ° C.
shelf life
3 years
Deystvuyushtee substance
Metoclopramide
dosage form
injection
Possible product names
metoclopramide ampoules 5 mg / ml, 2 ml, 10 pcs.
Novosibkhimpharm, Russia
metoclopramide ampoules 5 mg / ml, 2 ml, 10 pcs. (metoclopramide) florida in pharmacy online. Cheap price, instruction, side effects, dosage. metoclopramide ampoules 5 mg / ml, 2 ml, 10 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.
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