Mexidol tablets 0.125 g, 50 pcs. (etylmetylhydroksypyrydyna succinate succinate succinate)
Special Price
$25.50
Regular Price
$30.00
In stock
SKU
newyork462423
Latin name
Mexidolum Buy Mexidol tablets 0.125 g, 50 pcs. (etylmetylhydroksypyrydyna succinate succinate succinate) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Mexidolum Buy Mexidol tablets 0.125 g, 50 pcs. (etylmetylhydroksypyrydyna succinate succinate succinate) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Latin name
Mexidolum
Release form
Tablets, coated with a white to white cream-colored shade, biconvex
in the cross section, 2 layers are visible: the inner (core) gray or cream-gray shade and the outer white or creamy white shade.
packaging 10 pcs - blister packagings (5) - packs of cardboard.
Pharmacological action
Mexidol® is an inhibitor of free radical processes, a membrane protector with antihypoxic, stress-protective, nootropic, anticonvulsant and anxiolytic effects. The drug increases the body's resistance to the effects of various damaging factors (shock, hypoxia and ischemia, cerebrovascular accident, intoxication with alcohol and antipsychotics (antipsychotics)).
The mechanism of action of Mexidol® is due to its antioxidant, antihypoxic and membrane protective effect. It inhibits lipid peroxidation, increases the activity of superoxide dismutase, increases the lipid-protein ratio, reduces the viscosity of the membrane, and increases its fluidity. Mexidol® modulates the activity of membrane-bound enzymes (calcium independent phosphodiesterase, adenylate cyclase, acetylcholinesterase), receptor complexes (benzodiazepine, GABA, acetylcholine), which enhances their ability to bind to ligands, helps preserve the structural and functional organization of biomembranes, neurotransmitter transport and improved synaptic transmission.
Mexidol® boosts dopamine levels in the brain. It causes an increase in the compensatory activation of aerobic glycolysis and a decrease in the degree of inhibition of oxidative processes in the Krebs cycle under hypoxia with an increase in the content of ATP and creatine phosphate, activation of the energy-synthesizing functions of mitochondria, and stabilization of cell membranes.
The drug improves metabolism and blood supply to the brain, improves microcirculation and rheological properties of blood, reduces platelet aggregation. It stabilizes the membrane structures of blood cells (red blood cells and platelets) during hemolysis. It has a lipid-lowering effect, reduces the content of total cholesterol and low density lipoproteins.
Antistress action is manifested in the normalization of post-stress behavior, somatovegetative disorders, restoration of sleep-wakefulness cycles, impaired learning and memory processes, reduction of dystrophic and morphological changes in various brain structures.
Mexidol® has a pronounced antitoxic effect in withdrawal symptoms. It eliminates the neurological and neurotoxic manifestations of acute alcohol intoxication, restores behavioral disorders, autonomic functions, and is also able to remove cognitive impairment caused by prolonged intake of ethanol and its cancellation. Under the influence of Mexidol®, the effect of tranquilizing, antipsychotic, antidepressant, hypnotics and anticonvulsants is enhanced, which allows to reduce their doses and reduce side effects. Mexidol® improves the functional state of the ischemic myocardium. In conditions of coronary insufficiency, it increases the collateral blood supply to the ischemic myocardium, helps to preserve the integrity of cardiomyocytes and maintain their functional activity. Effectively restores myocardial contractility with reversible cardiac dysfunction.
Pharmacokinetics
Absorption
With the introduction of Mexidol in doses of 400-500 mg Cmax in plasma is 3.5-4.0 μg / ml and is achieved within 0.45-0.5 hours.
Distribution of
After i / m administration, the drug is determined in blood plasma for 4 hours The average retention time of the drug in the body is 0.7-1.3 hours.
Excretion of
It is excreted in the urine mainly in a glucuronoconjugated form and in small amounts unchanged.
Indications
the consequences of acute cerebrovascular accidents, including after in the subcompensation phase as prophylactic courses
mild traumatic brain injury, consequences of traumatic brain injuries
encephalopathy of various origins (discirculatory, dysmetabolic, post-traumatic, mixed)
autonomic dystonia syndrome
pulmonary necrotizing neurotrophic neurotic disorders
conditions after acute intoxication with antipsychotics
asthenic conditions, as well as for the prevention of Itijah somatic diseases under the influence of extreme factors and
exposure to extreme stress (stress) factors.
coronary heart disease as part of the complex therapy
relief of withdrawal symptoms in alcoholism with a predominance of neurosis and vegetative-vascular disorders, post-withdrawal disorders
Contraindications
increased individual sensitivity to the drug
acute renal failure
acute liver failure.
Due to insufficient knowledge of the effect of the drug - childhood, pregnancy, breastfeeding.
Use during pregnancy and lactation
There have been no strictly controlled clinical trials of the safety of the drug MexidolВ® during pregnancy and lactation.
Composition
Active ingredient:
ethylmethylhydroxypyridine succinate (2-ethyl-6-methyl-3-hydroxypyridine succinate) - 125.0 mg
Excipients:
lactose monohydrate - 97.5 mg, 25.0 mg, ppm
magnesium stearate - 2.50 mg
Film coat:
opadra II white 33G28435 - 7.5 mg (hypromellose - 3.0 mg, titanium dioxide - 1.875 mg, lactose monohydrate - 1.575 mg, polyethylene glycol (macrogol) - 0.6 mg, triacetin - 0.45 mg)
Side effects
From the digestive system: rarely - nausea, dry mouth.
Other: rarely - allergic reactions.
The drug interaction
Mexidol® is combined with all drugs used to treat somatic diseases.
When used together, Mexidol® enhances the effects of benzodiazepine derivatives, antidepressants, anxiolytics, antiparkinsonian and anticonvulsants.
Mexidol® reduces the toxic effects of ethanol.
Overdose
Symptoms: possible drowsiness.
Storage conditions
In a dry, dark place at a temperature of no higher than 25 ° C.
Keep out of the reach of children.
Expiration
3 years.
Do not use after the expiry date stated on the package
Deystvuyuschee substances
Эtylmetylhydroksypyrydyna succinate
Dosage form
tablets dosage form
tablets
Farmasoft, Russia
Mexidol tablets 0.125 g, 50 pcs. (etylmetylhydroksypyrydyna succinate succinate succinate) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Mexidol tablets 0.125 g, 50 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
Mexidolum
Release form
Tablets, coated with a white to white cream-colored shade, biconvex
in the cross section, 2 layers are visible: the inner (core) gray or cream-gray shade and the outer white or creamy white shade.
packaging 10 pcs - blister packagings (5) - packs of cardboard.
Pharmacological action
Mexidol® is an inhibitor of free radical processes, a membrane protector with antihypoxic, stress-protective, nootropic, anticonvulsant and anxiolytic effects. The drug increases the body's resistance to the effects of various damaging factors (shock, hypoxia and ischemia, cerebrovascular accident, intoxication with alcohol and antipsychotics (antipsychotics)).
The mechanism of action of Mexidol® is due to its antioxidant, antihypoxic and membrane protective effect. It inhibits lipid peroxidation, increases the activity of superoxide dismutase, increases the lipid-protein ratio, reduces the viscosity of the membrane, and increases its fluidity. Mexidol® modulates the activity of membrane-bound enzymes (calcium independent phosphodiesterase, adenylate cyclase, acetylcholinesterase), receptor complexes (benzodiazepine, GABA, acetylcholine), which enhances their ability to bind to ligands, helps preserve the structural and functional organization of biomembranes, neurotransmitter transport and improved synaptic transmission.
Mexidol® boosts dopamine levels in the brain. It causes an increase in the compensatory activation of aerobic glycolysis and a decrease in the degree of inhibition of oxidative processes in the Krebs cycle under hypoxia with an increase in the content of ATP and creatine phosphate, activation of the energy-synthesizing functions of mitochondria, and stabilization of cell membranes.
The drug improves metabolism and blood supply to the brain, improves microcirculation and rheological properties of blood, reduces platelet aggregation. It stabilizes the membrane structures of blood cells (red blood cells and platelets) during hemolysis. It has a lipid-lowering effect, reduces the content of total cholesterol and low density lipoproteins.
Antistress action is manifested in the normalization of post-stress behavior, somatovegetative disorders, restoration of sleep-wakefulness cycles, impaired learning and memory processes, reduction of dystrophic and morphological changes in various brain structures.
Mexidol® has a pronounced antitoxic effect in withdrawal symptoms. It eliminates the neurological and neurotoxic manifestations of acute alcohol intoxication, restores behavioral disorders, autonomic functions, and is also able to remove cognitive impairment caused by prolonged intake of ethanol and its cancellation. Under the influence of Mexidol®, the effect of tranquilizing, antipsychotic, antidepressant, hypnotics and anticonvulsants is enhanced, which allows to reduce their doses and reduce side effects. Mexidol® improves the functional state of the ischemic myocardium. In conditions of coronary insufficiency, it increases the collateral blood supply to the ischemic myocardium, helps to preserve the integrity of cardiomyocytes and maintain their functional activity. Effectively restores myocardial contractility with reversible cardiac dysfunction.
Pharmacokinetics
Absorption
With the introduction of Mexidol in doses of 400-500 mg Cmax in plasma is 3.5-4.0 μg / ml and is achieved within 0.45-0.5 hours.
Distribution of
After i / m administration, the drug is determined in blood plasma for 4 hours The average retention time of the drug in the body is 0.7-1.3 hours.
Excretion of
It is excreted in the urine mainly in a glucuronoconjugated form and in small amounts unchanged.
Indications
the consequences of acute cerebrovascular accidents, including after in the subcompensation phase as prophylactic courses
mild traumatic brain injury, consequences of traumatic brain injuries
encephalopathy of various origins (discirculatory, dysmetabolic, post-traumatic, mixed)
autonomic dystonia syndrome
pulmonary necrotizing neurotrophic neurotic disorders
conditions after acute intoxication with antipsychotics
asthenic conditions, as well as for the prevention of Itijah somatic diseases under the influence of extreme factors and
exposure to extreme stress (stress) factors.
coronary heart disease as part of the complex therapy
relief of withdrawal symptoms in alcoholism with a predominance of neurosis and vegetative-vascular disorders, post-withdrawal disorders
Contraindications
increased individual sensitivity to the drug
acute renal failure
acute liver failure.
Due to insufficient knowledge of the effect of the drug - childhood, pregnancy, breastfeeding.
Use during pregnancy and lactation
There have been no strictly controlled clinical trials of the safety of the drug MexidolВ® during pregnancy and lactation.
Composition
Active ingredient:
ethylmethylhydroxypyridine succinate (2-ethyl-6-methyl-3-hydroxypyridine succinate) - 125.0 mg
Excipients:
lactose monohydrate - 97.5 mg, 25.0 mg, ppm
magnesium stearate - 2.50 mg
Film coat:
opadra II white 33G28435 - 7.5 mg (hypromellose - 3.0 mg, titanium dioxide - 1.875 mg, lactose monohydrate - 1.575 mg, polyethylene glycol (macrogol) - 0.6 mg, triacetin - 0.45 mg)
Side effects
From the digestive system: rarely - nausea, dry mouth.
Other: rarely - allergic reactions.
The drug interaction
Mexidol® is combined with all drugs used to treat somatic diseases.
When used together, Mexidol® enhances the effects of benzodiazepine derivatives, antidepressants, anxiolytics, antiparkinsonian and anticonvulsants.
Mexidol® reduces the toxic effects of ethanol.
Overdose
Symptoms: possible drowsiness.
Storage conditions
In a dry, dark place at a temperature of no higher than 25 ° C.
Keep out of the reach of children.
Expiration
3 years.
Do not use after the expiry date stated on the package
Deystvuyuschee substances
Эtylmetylhydroksypyrydyna succinate
Dosage form
tablets dosage form
tablets
Farmasoft, Russia
Mexidol tablets 0.125 g, 50 pcs. (etylmetylhydroksypyrydyna succinate succinate succinate) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Mexidol tablets 0.125 g, 50 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
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