Minolexin capsules 50 mg, 20 pcs. (Minocycline)

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Latin name

MINOLEXIN Buy Minolexin capsules 50 mg, 20 pcs. (Minocycline) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Latin name

MINOLEXIN

Packaging

20 pcs.

Pharmacological action of

Minolexin is a semi-synthetic antibiotic from the tetracycline group. It has a bacteriostatic effect on cells of sensitive strains of microorganisms due to reversible inhibition of protein synthesis at the level of 30S ribosome subunits. It has a wide range of antibacterial activity.

Sensitivity of microorganisms: Some of the microorganisms listed below have shown resistance to minocycline, therefore laboratory tests are recommended before use. sensitivity study. Antibiotics of the tetracycline group are not recommended for the treatment of streptococcal and staphylococcal infections, unless

sensitivity of microorganisms to minocycline is shown.

Gram-positive aerobic: Bacillus anthracis, Listeria monocytogenes, Staphylococcus aureus, Streptococcus pneumoniae.

Gram-negative aerobic: Bartonella bacilliformis, Brucella species, Calymmatobacterium granulomatis, Campylobacterfetils, Francisella tularensis, Haemophilus ducreyi, Vibrio cholerae, Yersinia pestis.

Indications

Minolexin is used to treat the following diseases, provided pathogenic microorganisms are sensitive: Acne

Skin infections

Spotted fever, typhoid fever, typhoid fever, respiratory tract disease Ornithosis

Trachoma (infectious keratoconjunctivitis)

Conjunctivitis with inclusions (paratrachoma)

Non-neococcal urethritis, infection of the cervical canal and anus adult

Cyclic fever

Chancroid

Plague

Tularemia

Cholera

Brucellosis

Bartonellosis

granuloma inguinale

Syphilis

Gonorrhea

Yaws (tropical granuloma, non-venereal syphilis)

Listerrioz

Anthrax

Angina Vincent

Actinomycosis

In the case of acute intestinal amebiasis, minocycline may be used as a supplement to amoebicidal drugs.

In severe acne. minocycline can be used as adjunctive therapy.

Oral administration of minocycline is indicated for asymptomatic carriage of Neisseria mepigitidis to eradicate meningococci from the nasopharynx.

Contraindications

Hypersensitivity to minocycline, tetracyclines and other components of the

preparation Porphyria

Severe hepatic and renal failure

Leukopenia

Pregnancy breastfeeding

Systemic lupus erythematosus

Children under 8 years of age have been diagnosed with acute illness

malabsorption Precautions: impaired liver and kidney function, concomitant use with hepatotoxic drugs.

Composition

Active ingredient: minocycline hydrochloride dihydrate (in terms of minocycline) 50 mg

Excipients: microcrystalline cellulose, low molecular weight povidone, potato starch, magnesium stearate, lactose monohydrate.

Dosage and Administration

Inside, after meals. It is recommended to drink plenty of fluids (can be milk) for. reduce the risk of irritation and ulceration in the esophagus.

The initial dose of Minolexin is 200 mg (2 capsules of 100 mg or 4 capsules of 50 mg), then take 100 mg (1 capsule of 100 mg or 2 capsules of 50 mg) every 12 hours (twice a day) .

The maximum daily dose should not exceed 400 mg.

Urogenital and anogenital infections caused by chlamydia and ureaplasma: 100 mg (1 capsule of 100 mg or 2 capsules of 50 mg) every 12 hours for 7-10 days.

Inflammatory diseases of the pelvic organs in women in the acute stage: 100 mg (1 capsule of 100 mg or 2 capsules of 50 mg) every 12 hours, sometimes in combination with cephalosporins.

Primary syphilis in patients. with hypersensitivity to penicillins: 100 mg (1 capsule of 100 mg or 2 capsules of 50 mg) twice a day for 10 to 15 days.

Gonorrhea: 100 mg (1 capsule of 100 mg or 2 capsules of 50 mg) twice a day for 4-5 days, or once 300 mg.

Uncomplicated gonococcal infections (excluding urethritis and anorectal infections) in men: initial dose - 200 mg (2 capsules of 100 mg or 4 capsules of 50 mg), maintenance dose - 100 mg (1 capsule of 100 mg or 2 capsules of 50 mg) every 12 hours for at least 4 days, followed by a microbiological assessment of recovery 2-3 days after stopping the drug.

Uncomplicated gonococcal urethritis in men: 100 mg (1 capsule of 100 mg or 2 capsules of 50 mg) every 12 hours for 5 days.

Acne: 50 mg (1 capsule of 50 mg) per day, long course of 6-12 weeks.

Side effects of the digestive system: anorexia, nausea, vomiting, diarrhea, dyspepsia, stomatitis, glossitis, dysphagia, hypoplasia of tooth enamel, enterocolitis, pseudomembranous colitis, pancreatitis, inflammatory

lesions (including fungal) in the oral cavity and anogenital region, hyperbilirubinemia, cholestasis, an increase in the content of “liver” enzymes, liver failure, including terminal, hepatitis, including autoimmune.

From the genitourinary system: candidiasis vulvovaginitis, interstitial nephritis, dose-dependent increase in urea in the blood plasma.

From the skin: baldness, erythema nodosum, nail pigmentation, itching, toxic epidermal necrosis, vasculitis, maculopapular and erythematous rash, Stevens-Johnson syndrome, exfoliative dermatitis, balanitis.

From the respiratory tract: shortness of breath, bronchospasm, exacerbation of asthma, pneumonia.

From the musculoskeletal system: arthralgia, arthritis, limitation of mobility and swelling of the joints, discoloration of bone tissue, muscle pain (myalgia).

Allergic reactions: urticaria, angioedema, polyarthralgia, anaphylactic reactions (including shock), anaphylactoid purpura (Purple Schoenlein Genoch), pericarditis, exacerbations of systemic lupus erythematosus, pulmonary infiltration, or eosinosis.

From the hemopoietic organs: agranulocytosis, hemolytic anemia, tr6mbocytopenia, leukopenia, neutrocytopenia, pancytopenia, eosinopenia, eosiophilia.

From the central nervous system: cramps, dizziness, numbness (including limbs), lethargy, vertigo, increased intracranial pressure in adults, headaches.

From the sensory organs: tinnitus and hearing impairment.

Metabolism: Thyroid: a single case of malignant neoplasms, discoloration (according to the results of patho-morphological studies), impaired function.

Others: Change in color of the oral cavity (tongue, gum, palate), change in color of tooth enamel, fever, discharge color (for example, sweat).

Drug Interactions

Tetracycline drugs decrease the prothrombin activity of blood plasma, which may necessitate lower doses of anticoagulants in patients undergoing anticoagulant therapy.

Due to Since bacteriostatic drugs affect the bactericidal effect of penicillins, the simultaneous administration of penicillin and tetracycline groups should be avoided.

The absorption of tetracyclines is impaired when taken with antacids containing aluminum, calcium, magnesium or iron-containing drugs, which can lead to a decrease in the effectiveness of antibiotic therapy.

There have been cases of terminal renal toxicity while taking methoxyfruran and drugs of the

group of tetracyclines.

The simultaneous use of antibiotics of the tetracycline group and oral contraceptives can lead to a decrease in the effectiveness of contraception.

Isotretinoin should be avoided immediately before, simultaneously and immediately after taking minocycline, since both drugs can cause a benign increase in intracranial pressure.

Concomitant use of tetracycline drugs with ergot alkaloids and their derivatives increases the risk of ergotism.

Overdose

Symptoms: Dizziness, nausea, and vomiting are most commonly observed.

Treatment: The selective antidote for minocycline is currently unknown. In case of an overdose, it is necessary to stop taking the drug, provide symptomatic treatment and supportive therapy. Hemo- and peritoneal dialysis remove minocycline in small quantities.

Storage conditions

In a place protected from moisture and light, at temperatures. is not higher than 25 ° C. Keep out of reach of children.

Expiration

2 years.

active substance

Minocycline

Pharmacy terms

Prescription

lekarstvennaja form

kapsul

Prescribing

Adults as prescribed by a doctor, Children over 8 years old, Children as prescribed by a doctor



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