Nazivin Sensitive spray nasal 22, 5 mcg / dose 10 ml (oxymetazoline)

Latin name

Nasivin Sansitive

Release form

Nasal spray.

Packing

Bottle of 10 ml.

Pharmacological action

Nazivin® Sensitive (oxymetazoline) has a vasoconstrictor effect. When applied locally to the inflamed mucous membrane of the nasal cavity, it reduces its swelling and discharge from the nose. Restores nasal breathing.

Elimination of edema of the mucous membrane of the nasal cavity helps to restore aeration of the paranasal sinuses of the nasal cavity, middle ear cavity, which reduces the likelihood of bacterial complications (sinusitis, sinusitis, otitis media).

When applied topically at therapeutic concentrations, it does not irritate or cause hyperemia of the nasal mucosa.

Oxymethazoline begins to act quickly, within a few minutes. Duration of action of Nazivin® Sensitive up to 12 hours.

Pharmacokinetics. With topical intranasal use, oxymetazoline does not have a systemic effect. The half-life of oxymetazoline when administered intranasally is 35 hours. 2.1% of oxymetazoline is excreted in the urine and about 1.1% with feces.

Indications

Colds or viral infections of the upper respiratory tract, accompanied by a runny nose, sinusitis, eustachiitis, otitis media, rhinitis of any etiology

To eliminate edema before diagnostic procedures in the nasal passages.

Contraindications

Atrophic rhinitis

Angle-closure glaucoma

Hypersensitivity to the drug.

Nazivin® Sensitive Nasal Spray Spray (22.5 mcg / dose) is contraindicated in children under 6 years of age.

Precautions for: increased intraocular pressure

chronic heart failure

arterial hypertension, angina pectoris

arrhythmias

chronic renal failure

in patients with prostatic hyperplasia with clinical symptoms (urinary retention)

severe atherosclerosis

with hyperthyroidism

diabetes mellitus

pheochromocytoma.

Use during pregnancy and lactation

When using during pregnancy or breastfeeding, the recommended dose should not be exceeded.

The drug can be used only if the potential benefit to the mother outweighs the potential risk to the fetus and baby.

Composition of

1 ml of the solution contains:

Active ingredient:

Oxymethazoline hydrochloride 0.500 mg

Excipients:

citric acid monohydrate 0.609 mg

sodium citrate dihydrate 3.823 mg

rgp 85 mg gldrgp 85 grld

Total: 1,008.00 mg, equivalent to 1 ml.

Dosage and Administration

Nazivin® Sensitive Nasal Spray Dosage 22.5 mcg / dose is intended for intranasal administration.

Adults and children over 6 years of age: 1 injection of Nazivin® Sensitive nasal spray dosed 22.5 mcg / dose in each nostril 2-3 times a day. If symptoms intensify or improvement does not occur within 3 days, you should consult your doctor. In the recommended dose, without consulting a doctor, use no more than 7 days.

Doses higher than recommended may only be used under medical supervision. A single injection with a volume of 45 μl contains 22.5 μg of oxymetazoline hydrochloride - for Nazivin® Sensitive Nasal Spray, dosed 22.5 μg / dose.

Side effects

Infrequently:

burning or dry nasal mucosa, sneezing, nosebleeds, Quincke's edema, pruritus. In rare cases: after the effect of the use of the drug Nazivin® Sensitive disappears, a feeling of nasal congestion (reactive hyperemia).

Rarely:

increased blood pressure, headache, dizziness, palpitations, tachycardia, anxiety, irritability, sleep disturbance (in children), nausea, insomnia, exanthema, impaired vision (in the eyes).

Very rare:

fatigue, drowsiness, restlessness, hallucinations,

cramps, respiratory arrest (in infants).

Prolonged continuous use of vasoconstrictor drugs can lead to tachyphylaxis, atrophy of the nasal mucosa and recurrent edema of the nasal mucosa (drug rhinitis).



overdose Symptoms (after significant overdose or accidental ingestion):

pupil constriction, nausea, vomiting, cyanosis, fever, tachycardia, arrhythmia, vascular insufficiency, arterial hypertension, arterial hypertension Mental disorders, as well as CNS function depression, accompanied by drowsiness, decreased body temperature, bradycardia, arterial hypotension, respiratory arrest, and possible coma development may occur.

Treatment:

gastric lavage, activated charcoal and urgent medical attention.

Storage Conditions

In a dark place at a temperature not exceeding 25 ° C.

Shelf life

3 years.

Deystvuyushtee substance

Oxymethazoline

prescriptions ka from drugstore

Without prescription

Dosage form

spray nasal

For

Appointment

vasoconstrictive

Ursafarm Arzneimittel, Germany



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