Niperten tablets 5 mg, 100 pcs. (bisoprolol)
Special Price
$22.95
Regular Price
$27.00
In stock
SKU
newyork467591
Release form
Film-coated tablets. Buy Niperten tablets 5 mg, 100 pcs. (bisoprolol) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Film-coated tablets. Buy Niperten tablets 5 mg, 100 pcs. (bisoprolol) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Release form
Film-coated tablets.
Packing
100 pcs.
Pharmacological action
Niperten has a hypotensive, antianginal, antiarrhythmic effect.
Indications
arterial hypertension
ischemic heart disease: prevention of angina attacks
CHF.
Special instructions
Influence on the ability to drive vehicles and control mechanisms:
The question of the possibility of engaging in potentially dangerous activities that require increased attention and speed of psychomotor reactions should be decided only after evaluating the patient's individual reaction to the drug (especially at the beginning of treatment, in connection with the possibility of developing dizziness).
Composition
1 tablet contains bisoprolol fumarate (2: 1) 5 mg.
Dosage and administration of
Niperten is taken orally, on an empty stomach in the morning, without chewing, once. It is recommended to take 5 mg once. If necessary, increase the dose to 10 mg once a day. The maximum daily dose is 20 mg.
Side effects of the
From the central nervous system and peripheral nervous system: fatigue, weakness, dizziness, headache, sleep disturbances, depression, anxiety, confusion or short-term memory loss, hallucinations, asthenia, myasthenia gravis, paresthesia in the extremities (in patients with "Intermittent" lameness and Raynaud's syndrome), tremor, cramps (including calf muscles).
From the side of the organ of vision: visual impairment, decreased secretion of lacrimal fluid, dryness and soreness of the eyes, conjunctivitis.
From the cardiovascular system: sinus bradycardia, palpitations, impaired myocardial conduction, AV block (up to the development of complete lateral blockade and cardiac arrest), arrhythmias, weakened myocardial contractility, development (aggravation) of heart failure (ankle swelling, stop shortness of breath), decreased blood pressure, orthostatic hypotension, the manifestation of angiospasm (increased disturbance of peripheral circulation, cooling of the lower extremities, Raynaud's syndrome), chest pain.
From the digestive system: dry oral mucosa, nausea, vomiting, abdominal pain, constipation or diarrhea, impaired liver function (dark urine, yellowness of the sclera or skin, cholestasis), taste changes.
From the respiratory system: nasal congestion, difficulty breathing when prescribed in high doses (loss of selectivity) and / or in predisposed patients - laryngo- and bronchospasm.
From the endocrine system: hyperglycemia (in patients with non-insulin-dependent diabetes), hypoglycemia (in patients receiving insulin), hypothyroid state.
Allergic reactions: pruritus, rash, urticaria.
From the skin: increased sweating, flushing of the skin, exanthema, psoriasis-like skin reactions, exacerbation of the symptoms of psoriasis, alopecia.
Laboratory parameters: thrombocytopenia (unusual bleeding and hemorrhage), agranulocytosis, leukopenia, changes in liver enzyme activity (increased ALT, ACT, bilirubin, triglycerides.
Effect on the fetus: intrauterine growth retardation, hypoglycemia, s bradycardia. , arthralgia, decreased libido, decreased potency, withdrawal syndrome (increased angina attacks, increased blood pressure)
Drug Interactions
Allergens used for immunotherapy, or allergen extracts for skin tests increase the risk of severe systemic allergic reactions or anaphylaxis in patients receiving bisoprolol.
Iodine-containing radiopaque agents for iv administration increase the risk of anaphylactic reactions.
Phenytoin with iv administration, funds for inhalation anesthesia (hydrocarbon derivatives) increase the severity of the cardio-depressant effect of bisoprolol and the likelihood of lowering blood pressure.
Niperten changes the effectiveness of insulin and hypoglycemic agents for oral administration, masks the symptoms of developing hypoglycemia (tachycardia, increased blood pressure).
Bisoprolol reduces the clearance of lidocaine and xanthines (except theophylline) and increases their concentration in blood plasma, especially in patients with initially increased clearance of theophylline under the influence of smoking.
Antihypertensive effect is weakened by NSAIDs (sodium ion retention and prostaglandin synthesis blockade by the kidneys), corticosteroids and estrogens (sodium ion retention).
Cardiac glycosides, methyldopa, reserpine and guanfacine, slow calcium channel blockers (verapamil, diltiazem), amiodarone and other antiarrhythmic drugs increase the risk of developing or exacerbating bradycardia, AV blockade, cardiac arrest and heart failure.
Nifedipine can lead to a significant decrease in blood pressure.
Diuretics, clonidine, sympatholytics, hydralazine and other antihypertensive drugs can lead to an excessive decrease in blood pressure.
Extends the action of non-depolarizing muscle relaxants and increases the anticoagulant effect of coumarins.
Tri- and tetracyclic antidepressants, antipsychotics (antipsychotics), ethanol, sedative and hypnotic drugs increase CNS depression.
The simultaneous use with MAO inhibitors is not recommended, due to a significant increase in the hypotensive effect, the treatment interval between taking MAO inhibitors and bisoprolol should be at least 14 days.
Non-hydrogenated ergot alkaloids increase the risk of peripheral circulation disorders.
Ergotamine increases the risk of developing peripheral circulatory disorders sulfasalazine increases the concentration of bisoprolol in blood plasma rifampicin reduces.
Overdose
Symptoms: arrhythmia, ventricular extrasystole, severe bradycardia, AV block, marked decrease in blood pressure, chronic heart failure, cyanosis of fingernails or palms of the fingers, difficulty breathing, bronchospasm, dizziness, fainting, convulsions.
Treatment: gastric lavage and administration of absorbent agents. Symptomatic therapy: in case of developed AV block, intravenous administration of 1-2 mg of atropine, epinephrine or temporary setting of a pacemaker with ventricular extrasystole - lidocaine (class IA drugs are not used) with a decrease in blood pressure - the patient should be in the Trendelenburg position if there are no signs of pulmonary edema - in / in the introduction of plasma-replacing solutions, with inefficiency - the introduction of epinephrine, dopamine, dobutamine (to maintain a chronotropic and inotropic effect and eliminate a pronounced decrease in blood pressure) with heart failure nostalgia - cardiac glycosides, diuretics, glucagon for convulsions - iv diazepam for bronchospasm - beta2-adrenostimulators inhaled.
Storage Conditions
In a dark place at a temperature not exceeding 25 ° C.
Expiration
2 years.
active substance
bisoprolol
Terms of dispatch from
pharmacies Prescription
lekarstvennaja form
tablets
KRKA d.d. Novo mesto AO, Slovenia
Niperten tablets 5 mg, 100 pcs. (bisoprolol) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Niperten tablets 5 mg, 100 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
Film-coated tablets.
Packing
100 pcs.
Pharmacological action
Niperten has a hypotensive, antianginal, antiarrhythmic effect.
Indications
arterial hypertension
ischemic heart disease: prevention of angina attacks
CHF.
Special instructions
Influence on the ability to drive vehicles and control mechanisms:
The question of the possibility of engaging in potentially dangerous activities that require increased attention and speed of psychomotor reactions should be decided only after evaluating the patient's individual reaction to the drug (especially at the beginning of treatment, in connection with the possibility of developing dizziness).
Composition
1 tablet contains bisoprolol fumarate (2: 1) 5 mg.
Dosage and administration of
Niperten is taken orally, on an empty stomach in the morning, without chewing, once. It is recommended to take 5 mg once. If necessary, increase the dose to 10 mg once a day. The maximum daily dose is 20 mg.
Side effects of the
From the central nervous system and peripheral nervous system: fatigue, weakness, dizziness, headache, sleep disturbances, depression, anxiety, confusion or short-term memory loss, hallucinations, asthenia, myasthenia gravis, paresthesia in the extremities (in patients with "Intermittent" lameness and Raynaud's syndrome), tremor, cramps (including calf muscles).
From the side of the organ of vision: visual impairment, decreased secretion of lacrimal fluid, dryness and soreness of the eyes, conjunctivitis.
From the cardiovascular system: sinus bradycardia, palpitations, impaired myocardial conduction, AV block (up to the development of complete lateral blockade and cardiac arrest), arrhythmias, weakened myocardial contractility, development (aggravation) of heart failure (ankle swelling, stop shortness of breath), decreased blood pressure, orthostatic hypotension, the manifestation of angiospasm (increased disturbance of peripheral circulation, cooling of the lower extremities, Raynaud's syndrome), chest pain.
From the digestive system: dry oral mucosa, nausea, vomiting, abdominal pain, constipation or diarrhea, impaired liver function (dark urine, yellowness of the sclera or skin, cholestasis), taste changes.
From the respiratory system: nasal congestion, difficulty breathing when prescribed in high doses (loss of selectivity) and / or in predisposed patients - laryngo- and bronchospasm.
From the endocrine system: hyperglycemia (in patients with non-insulin-dependent diabetes), hypoglycemia (in patients receiving insulin), hypothyroid state.
Allergic reactions: pruritus, rash, urticaria.
From the skin: increased sweating, flushing of the skin, exanthema, psoriasis-like skin reactions, exacerbation of the symptoms of psoriasis, alopecia.
Laboratory parameters: thrombocytopenia (unusual bleeding and hemorrhage), agranulocytosis, leukopenia, changes in liver enzyme activity (increased ALT, ACT, bilirubin, triglycerides.
Effect on the fetus: intrauterine growth retardation, hypoglycemia, s bradycardia. , arthralgia, decreased libido, decreased potency, withdrawal syndrome (increased angina attacks, increased blood pressure)
Drug Interactions
Allergens used for immunotherapy, or allergen extracts for skin tests increase the risk of severe systemic allergic reactions or anaphylaxis in patients receiving bisoprolol.
Iodine-containing radiopaque agents for iv administration increase the risk of anaphylactic reactions.
Phenytoin with iv administration, funds for inhalation anesthesia (hydrocarbon derivatives) increase the severity of the cardio-depressant effect of bisoprolol and the likelihood of lowering blood pressure.
Niperten changes the effectiveness of insulin and hypoglycemic agents for oral administration, masks the symptoms of developing hypoglycemia (tachycardia, increased blood pressure).
Bisoprolol reduces the clearance of lidocaine and xanthines (except theophylline) and increases their concentration in blood plasma, especially in patients with initially increased clearance of theophylline under the influence of smoking.
Antihypertensive effect is weakened by NSAIDs (sodium ion retention and prostaglandin synthesis blockade by the kidneys), corticosteroids and estrogens (sodium ion retention).
Cardiac glycosides, methyldopa, reserpine and guanfacine, slow calcium channel blockers (verapamil, diltiazem), amiodarone and other antiarrhythmic drugs increase the risk of developing or exacerbating bradycardia, AV blockade, cardiac arrest and heart failure.
Nifedipine can lead to a significant decrease in blood pressure.
Diuretics, clonidine, sympatholytics, hydralazine and other antihypertensive drugs can lead to an excessive decrease in blood pressure.
Extends the action of non-depolarizing muscle relaxants and increases the anticoagulant effect of coumarins.
Tri- and tetracyclic antidepressants, antipsychotics (antipsychotics), ethanol, sedative and hypnotic drugs increase CNS depression.
The simultaneous use with MAO inhibitors is not recommended, due to a significant increase in the hypotensive effect, the treatment interval between taking MAO inhibitors and bisoprolol should be at least 14 days.
Non-hydrogenated ergot alkaloids increase the risk of peripheral circulation disorders.
Ergotamine increases the risk of developing peripheral circulatory disorders sulfasalazine increases the concentration of bisoprolol in blood plasma rifampicin reduces.
Overdose
Symptoms: arrhythmia, ventricular extrasystole, severe bradycardia, AV block, marked decrease in blood pressure, chronic heart failure, cyanosis of fingernails or palms of the fingers, difficulty breathing, bronchospasm, dizziness, fainting, convulsions.
Treatment: gastric lavage and administration of absorbent agents. Symptomatic therapy: in case of developed AV block, intravenous administration of 1-2 mg of atropine, epinephrine or temporary setting of a pacemaker with ventricular extrasystole - lidocaine (class IA drugs are not used) with a decrease in blood pressure - the patient should be in the Trendelenburg position if there are no signs of pulmonary edema - in / in the introduction of plasma-replacing solutions, with inefficiency - the introduction of epinephrine, dopamine, dobutamine (to maintain a chronotropic and inotropic effect and eliminate a pronounced decrease in blood pressure) with heart failure nostalgia - cardiac glycosides, diuretics, glucagon for convulsions - iv diazepam for bronchospasm - beta2-adrenostimulators inhaled.
Storage Conditions
In a dark place at a temperature not exceeding 25 ° C.
Expiration
2 years.
active substance
bisoprolol
Terms of dispatch from
pharmacies Prescription
lekarstvennaja form
tablets
KRKA d.d. Novo mesto AO, Slovenia
Niperten tablets 5 mg, 100 pcs. (bisoprolol) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Niperten tablets 5 mg, 100 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.
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