Oraleur Allergen meadow grass pollen maintenance course, tablets, 90 pcs. (herb pollen allergens)

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newyork527761
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Release form

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Release form

tablets

Packing

90 pcs.

Pharmacological action

The exact mechanism of action of the allergen during allergen specific immunotherapy (ASIT) is not fully understood. The following biological changes are proven: the appearance of specific antibodies (IgG4), which play the role of “blocking antibodies”, a decrease in the level of specific IgE in plasma for a long period of time, a decrease in cell reactivity, involved in an allergic reaction, an increase in the activity of interaction between Th2 and Th1 T-lymphocytes and even Th0, leading to a positive change in the production of cytokines (a decrease in IL-4 and an increase in gamma interferon) that regulate the production of IgE. In addition, ASIT induces an immune response, which allows you to maintain immunobiological memory for a long period. The effectiveness of ASIT is higher when treatment is started in the early stages of the disease.

Indications

Allergen specific immunotherapy (ASIT) for patients with an allergic reaction of type 1 (IgE mediated), manifested in the form of rhinitis or rhinoconjunctivitis, with increased sensitivity to meadow pollen (hedgehog, common spikelet, summer grass, summer grass) meadow) confirmed by positive skin testing and / or elevated specific IgE content. Immunotherapy can be carried out for adults and children from 5 years of age.

Contraindications

Hypersensitivity to one of the excipients

beta-blocker therapy

uncontrolled or severe bronchial asthma (forced expiratory volume less than 70%)

severe immunodeficiencies and ulcerous diseases ulcerous diseases lichen planus, ulceration, mycosis)

hereditary galactose intolerance, Lapp lactase deficiency, impaired glucose absorption and galactoses.

Special instructions

For surgical operations in the rh cavity (including removal of tubes), therapy should be interrupted until it is completely cured (at least for 7 days). In the case of severe allergic reactions, the doctor may recommend taking epinephrine. It should be borne in mind that in patients taking tricyclic antidepressants, monoamine oxidase inhibitors, the risk of side effects on its administration increases up to death. There is no clinical experience with simultaneous vaccination and drug treatment. Vaccination can be carried out only after consulting a doctor. The drug does not affect the ability to drive vehicles and mechanisms.

Composition

Active e material: allergen extract from a mixture of grass pollen (cocksfoot, common spikelet bayberry, Lolium perenne, Poa pratense, timothy grass) in equal proportions, TS 100 and TS 300

Excipients: microcrystalline cellulose - 12.5 mg, croscarmellose sodium - 2.5 mg, colloidal silicon dioxide - 0.5 mg, magnesium stearate - 0.7 mg, lactose monohydrate - up to 100 mg

Dosage and administration of

Treatment with the drug should be carried out by an allergist. If the drug is used in pediatric practice, the doctor must have appropriate experience in treating children. It is recommended that you take the first pill under the supervision of a doctor to monitor the patient for 30 minutes. Treatment should be started 4 months before the expected flowering season, continued throughout the dusting season and stopped with its end. The drug is recommended to be taken in the morning on an empty stomach. The tablet should be placed under the tongue and kept until completely dissolved (for at least 1 minute), then swallow. Breaks in taking the drug should be avoided. Do not increase the dose after skipping the drug. If the pass in taking the drug is less than 7 days, it is recommended to resume taking the drug in the same dose at which the treatment was interrupted, and then follow the recommended regimen. With a long pass (more than 7 days), you should consult your doctor.

Side effects of the

From the immune system: allergic reactions.

From the side of the central nervous system and peripheral nervous system: headache, dizziness, change in taste, paresthesia.

From the side of the organ of vision: conjunctivitis, hyperemia.

On the part of the hearing organ: itchy ears, stuffy ear.

From the respiratory system: sore throat, difficulty breathing, swelling, rhinitis symptoms, sore throat, cough, suffocation, dysphonia.

From the gastrointestinal tract: itching, swelling, inflammation, numbness, tingling in the mouth, increased salivation, dry mouth, lips, vesicular eruptions in the mouth, on the lips, glossodynia, gastrointestinal disturbances, inflammation in the gastrointestinal tract.

From the skin and subcutaneous tissues: facial swelling, itching, urticaria, angioedema, eczema.

General disorders: fatigue, anxiety.

active substance

Allergens grass pollen

lekarstvennaja form

tablets

Stallergen, France



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