Osterepar tablets 70 mg, 4 pcs. (Alendronovaya acid)

Release form

Tablets.

Packing

4 pcs.

Pharmacological action

OSTEREPAR - an inhibitor of bone resorption. Sodium alendronate is a bisphosphonate, a synthetic analogue of pyrophosphate that binds bone hydroxyapatite. Being a non-hormonal specific inhibitor of osteoclast activity, it prevents bone resorption. Does not affect bone formation processes. Stimulates osteogenesis, restores a positive balance between resorption and bone restoration. Progressively increases bone mineral density (regulates calcium-phosphorus metabolism), promotes the formation of bone tissue of normal composition and structure.

Contraindications

- abnormalities of the esophagus and other factorsl

- period of lactation (breastfeeding)

- childhood

- vitamin D deficiency

- severe metabolic disorders

- hypersensitivity to the drug.

With caution, the drug should be used for diseases of the digestive tract in the exacerbation phase (dysphagia, esophageal diseases, gastritis, duodenitis, ulcer, serious gastrointestinal tract disease in the previous 12 months, for example, peptic ulcer, gastrointestinal bleeding, surgery, except for operations on spastic pylorus).



Composition Sodium alendronate trihydrate 91.37

mg Excipients: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, anhydrous colloidal silicon dioxide.

Dosage and administration of

The drug is taken orally. The recommended dose is 70 mg once a week. To ensure optimal absorption, the drug should be taken in the morning on an empty stomach, 2 hours (at least 30 minutes) before the first meal or liquid, washed down with plain drinking water. Other drinks, including mineral waters, food, a number of drugs can impair the absorption of alendronate.

In order to avoid local irritation of the mucous membrane of the oral cavity and esophagus in the morning, immediately after getting out of bed, drink at least 200 ml of plain water, then take a tablet without chewing and preventing it from dissolving in the mouth, during the next 30 minutes you can’t take a horizontal body position, after this period you should take breakfast. You can not take the pill in the morning, before getting out of bed or in the evening, after going to bed.

Treatment with alendronate should be supplemented with calcium and vitamin D.

Dosage adjustment is not required for elderly patients.

For KK> 35 ml / min dose adjustment is not required. In renal failure with CC <35 ml / min, the drug should not be prescribed due to lack of clinical experience.

Storage conditions

The drug should be stored out of the reach of children, in a dry, dark place at temperatures below 25 ° C.

Expiration

2 years.

Deystvuyuschee substances

Alendronovaya acid

dosage form

tablets

Polpharma, Poland



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