Panzinorm forte 20000 tablets, 30 pcs. (Pancreatin)

release form

coated tablets



packaging 30 pcs

Indications

insufficiency of exocrine pancreatic function (including chronic pancreatitis, cystic fibrosis)

chronic inflammatory dystrophic diseases of the stomach, intestines, liver, gall bladder after resection or irradiation of these organs, accompanied by a violation of digestion, flatulence, diarrhea (as part of combination therapy)

to improve food digestion in patients with normal gastrointestinal function in case of errors in

nutrition preparation for x-ray and ultrasound examination of abdominal organs.

Contraindications

hypersensitivity to pork protein or other components of the

drug acute pancreatitis, exacerbation of chronic pancreatitis

children under 3 years of age (for this dosage form) and up to 15 years (for children suffering from cystic fibrosis).

Use during pregnancy and lactation

The use of PanzinormВ® forte 20000 during pregnancy and lactation (breastfeeding) is possible only if if the expected positive effect of therapy exceeds the possible risk (due to the lack of clinical data confirming the safety of the use of pancreatic enzymes in this category of patients).

Dosage and Administration

Inside, with meals. Tablets should be taken whole, without chewing, with a sufficient amount of liquid.

The dose and duration of therapy is determined individually depending on the age and degree of pancreatic insufficiency.

Adults Panzinorm forte 20 000 is recommended to take (in the absence of other prescriptions) at the beginning of treatment, 1 tablet 3 times a day, during each main meal. It is possible to take Panzinorm forte 20,000 tablets while taking a light snack. If necessary, a single dose is increased by 2 times. The average daily dose is 1-2 tablets 3 times.

Before x-ray and ultrasound examinations - 2 tablets 2-3 times a day 2-3 days before the examination.

In children, the drug is used as directed by a doctor. Children over the age of 3 - 100 thousand units / day (in terms of lipase).

The duration of treatment can vary from a single dose or several days (if the digestive process is disturbed due to errors in the diet) to several months or years (if constant replacement therapy is necessary).

Side effects

Allergic reactions: flushing of the skin, skin rash, skin itching, sneezing, choking, lacrimation.

From the digestive system (with prolonged use in large doses): nausea, vomiting, abdominal pain (including intestinal colic), diarrhea, constipation, perianal irritation, irritation of the oral mucosa. With cystic fibrosis in case of exceeding the required dose of pancreatin (more than 10,000 units Heb. Pharm. lipases per 1 kg of body weight) it is possible to develop strictures (fibrotic colonopathy) in the ileocecal section and in the ascending colon.

Other: hyperuricemia, hyperuricosuria, folate deficiency.

Drug Interaction

When co-administered with pancreatin, the absorption of iron (clinically insignificant) and folic acid may be reduced. It is recommended that folate levels and / or folic acid be monitored periodically.

The acid-resistant coating of Pansinorm® Fort 20000 tablets dissolves in the duodenum. At low pH, pancreatin is not released in the duodenum.

Concurrent use of H2-histamine receptor blockers (cimetidine), hydrocarbonates, proton pump inhibitors can lead to increased pancreatin efficacy.

Overdose

Symptoms: nausea, vomiting, diarrhea, hyperuricosuria, hyperuricemia, perianal irritation, fibrous colonopathy (with cystic fibrosis).

Treatment: drug withdrawal, hydration, symptomatic therapy.

Storage conditions

In the dark place at a temperature of no higher than 25 ° C.

The Expiration of

is 3 years.

Deystvuyuschee substances

Pancreatin

dosage form

dosage form

tablets

KRKA d.d. Novo mesto AO, Slovenia



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