Pentas tablets retard 500 mg, 50 pcs. (mesalazine)

release form

coated tablets

Packing

50 pcs

Pharmacological action of

Pentas - anti-inflammatory. Pentasa reduces the formation of leukotrienes and cytokinins, neutralizes free radicals, and inhibits leukocyte chemotaxis.

Indications

Nonspecific ulcerative colitis Crohn's disease.

Contraindications

Hypersensitivity (including salicylates or other components of the drug) severe impaired liver and kidney function.

Use during pregnancy and lactation

During pregnancy and during lactation, it is prescribed only in cases where the positive effect exceeds the risk of possible side effects.

Composition

1 tablet contains:

Active ingredient: mesalazine 500 mg

Excipients: povidone ethyl cellulose magnesium stearate talc MCC up to 750 mg.

Dosage and administration

Inside, without chewing, if possible swallowing whole (to facilitate swallowing, they are divided into several parts or dissolved in water or juice immediately before administration), the dose is selected individually. For adults, with exacerbation of ulcerative colitis or Crohn’s disease, usually up to 4 g / day in several doses, the maintenance dose is 2 g / day in several doses for ulcerative colitis and 4 g / day in several doses for Crohn’s disease for children over 2 years old - usually 20 –30 mg / kg / day in divided doses.

Side effects

Sensation of discomfort in the abdomen, nausea, vomiting, headache, diarrhea, skin rash in the form of urticaria or eczema is very rare - muscle and joint pain, temporary hair loss, impaired liver and kidney function, pericarditis, myocarditis, pancreatitis, changes in the blood formula (leukopenia, granulocytopenia, thrombocytopenia, anemia).

Drug Interaction

With the simultaneous use of Pentas, it enhances the hypoglycemic action of sulfanyl urea derivatives, the ACS ulcerogenicity, the methotrexate toxicity and the action of anticoagulants.

With the simultaneous use of Pentas, the activity of furosemide, spironolactone, sulfonamides, rifampicin is attenuated.

With the simultaneous use of Pentas increases the effectiveness of uricosuric drugs.

When used with Pentas, it slows down the absorption of cyancobalamin.

Overdose

Symptoms: nausea, vomiting, gastralgia, weakness, drowsiness.

Treatment: gastric lavage, prescription laxatives, symptomatic therapy.

Storage conditions

The drug should be stored at a temperature not exceeding 25C.

The Expiration of

is 3 years.

Deystvuyuschee substances

mesalazane

Dosage form

Dosage form

tablets prolong.

Ferring GmbH, Germany



Pentas tablets retard 500 mg, 50 pcs. (mesalazine) newyork in pharmacy online. Cheap price, instruction, side effects, dosage. Pentas tablets retard 500 mg, 50 pcs. - Sale. PayPal accept. Free shipping newyork. Fast international shipping.