Polydex ear drops, 10.5 ml (Dexamethasone, neomycin, polymyxin B)

Release form

Drops.

Packaging

A bottle of yellow glass with a capacity of 10.5 ml, complete with a pipette, is placed in a cardboard box along with instructions for use.

Pharmacological action

Combined topical preparation in otolaryngology.

The therapeutic effect of Polydex is due to the anti-inflammatory effect of dexamethasone and the antibacterial effect of the antibiotics neomycin and polymyxin B. When these antibiotics are combined, the spectrum of antibacterial action on most gram-positive and gram-negative microorganisms causing infectious and inflammatory diseases of the outer and middle ear is expanded.

Neomycin is active against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae.

Polymyxin B is active against gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa.

Streptococcus spp is resistant to these antibiotics. (including Streptococcus pneumoniae).

Indications

- Otitis externa without damage to the eardrum

- infected eczema of the external auditory canal.

Contraindications

infectious or traumatic injuries of the eardrum

hypersensitivity to the components of the drug

suspected angle-closure glaucoma

concomitant use of MAO inhibitors

kidney disease accompanied by albuminuria srdlk lr.

Use during pregnancy and lactation

With prolonged treatment of pregnant women, there is a risk of an ototoxic effect on the fetus.

Special instructions

Do not administer under pressure. The simultaneous use of other aminoglycosides is not allowed. With topical use of neomycin or polymyxin B, the development of an allergic reaction may exclude the possibility of systemic use of other antibiotics that are similar in structure to neomycin and polymyxin B. When allergic to neomycin, cross-allergy with antibiotics, aminoglycosides, is possible.

Composition

Per 100 ml

Active ingredients:

Neomycin sulfate 1g, which corresponds to 650,000 ME.

Polymyxin B Sulfate 1,000,000ME.

Dexamethasone sodium metasulfobenzoate 0.100 g

Excipients: thiomersal, citric acid, 1N sodium hydroxide solution, macrogol 400, polysorbate 80, purified water qs up to 100 ml.

Dosage and administration

Adults: instill 1-5 drops in each ear 2 times a day for 6-10 days.

For children: instill 1-2 drops in each ear 2 times a day for 6-10 days. Duration of treatment - should not exceed -10 days.

Before using ear drops, it is recommended to warm the bottle by holding it in your hand, in order to avoid unpleasant sensations associated with the ingress of cold liquid into the ear. After instillation of the drug in one ear, you should tilt your head in the opposite direction for several minutes, and then instill in the other ear.

Side effects

Allergic reactions possible, rarely skin manifestations.

If the integrity of the eardrum is compromised, there is a risk of toxic effects on the auditory and vestibular apparatus.

Drug interactions

Incompatible with monomycin, streptomycin, gentamicin, amikacin, netilmicin (increased ototoxic effect).

overdose

Due to the low degree of absorption into the systemic circulation, an overdose is unlikely.

Storage conditions

At a temperature not exceeding 25 ° C out of the reach of children.

Shelf life

3 years.

Active ingredient

Dexamethasone, Neomycin, Polymyxin B

drugstore conditions

drugstore

Dosage form

drops ear

Possible product names

POLYDEX 10.5ML DROPS EARS

POLYDEX 10.5ML. EAR DROPS + PIPET

Polydex 10.5ml us.droplets

Polydex ear drops 10.5ml with

dropper POLYDEX DROPS USHN. 10,5ML

Laboratory Bouchard, France



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