Pyrantel tablets 250 mg, 3 pcs. (Pyrantel)

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Latin name

Pyrantel Buy Pyrantel tablets 250 mg, 3 pcs. (Pyrantel) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Latin name

Pyrantel

Packaging

3 pcs

Pharmacological action

Pyrantel - anthelmintic.

Blocks neuromuscular transmission in sensitive helminths.

Pharmacodynamics

Acts on helminths in the early phase of development and on mature forms, does not affect larvae in the migration stage. Active against Enterobius vermicularis, Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Trichostrongylus orientalis, Trichostrongylus colubriformis.

Pharmacokinetics

Practically not absorbed in the digestive tract. After oral administration in a single dose of 10 mg / kg body weight, Cmax is 0.005–0.13 μg / ml and is achieved within 1-3 hours. It is partially metabolized in the liver to N-methyl-1,3-propanediamine. It is excreted with feces (50% of the dose taken - unchanged) and with urine (about 7% - unchanged and as a metabolite).

Indications

Enterobiosis, ascariasis, hookworm infection, necatorosis.

Contraindications

Hypersensitivity.

Pregnancy and lactation

Adequate and well-controlled safety studies of the use of Pyrantel during pregnancy and lactation (breastfeeding) have not been conducted. The use of the drug during these periods is possible only if the intended benefit to the mother outweighs the potential risk to the fetus or child.

In experimental studies, no negative effect of Pyrantel on the fetus was found.

Composition

1 tablet contains:

Active ingredient: pyrantel 250 mg

Excipients: starch, gum, starch, gel , methyl parahydroxybenzoate, propyl parahydroxybenzoate, sodium carboxymethyl starch, talc, magnesium stearate, colloidal silicon dioxide (aerosil).

Dosage and Administration

Inside. The dose and frequency of administration are set individually, depending on the indications, age and body weight of the patient.

In case of ascariasis and enterobiasis, it is prescribed once at the rate of 10 mg / kg: for adults and children over 12 years old - 750 mg (for body weight over 75 kg - 1 g) for children from 6 months to 2 years old - 125 mg, 2-6 years old - 250 mg, 6-12 years - 500 mg. In order to avoid self-invasion, it is recommended that the course be repeated 3 weeks after the first dose.

With hookworm infection - 10 mg / kg in 1 dose for 3 days.

In case of necatorosis (severe forms) - 20 mg / kg / day for 2 days.

With isolated ascariasis, 5 mg / kg once.

Chew tablets before swallowing.

Side effects

From the nervous system and sensory organs: rarely - headache, dizziness, drowsiness, insomnia, weakness in some cases - hearing impairment, hallucinations, confusion, paresthesia.

From the digestive tract: nausea, vomiting, diarrhea, stomach pain rarely - increased activity of hepatic transaminases.

Other: skin rash, fever.

Storage Conditions

In a dark place, at a temperature of 15-25 ° C.

Term hodnosty

3 years

Active ingredient

Pyrantel

Terms leave through pharmacies

In retseptu

lekarstvennaja form

tablets

Ozon, Russia



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