Pyridoxine ampoules 5%, 1 ml, 10 pcs. (pyridoxine)

Packing

10 ampoules of 1 ml.

Pharmacological action

Pyridoxine hydrochloride - Vitamin B6. Phosphorylated and in the form of pyridoxalphosphate is part of enzymes that catalyze decarboxylation and transamination. It plays an important role in the metabolism of tryptophan, glutamic acid, cysteine, methionine, as well as in the transport of amino acids across the cell membrane. It is necessary for the activation of phosphorylase, for the formation of neurotransmitters, gamma-aminobutyric acid, glycine, serotonin. Participates in the exchange of vitamin B12, folic acid, in the synthesis of porphyrins, in the exchange of unsaturated fatty acids. It is used to activate metabolic processes in myofibrils, especially with myocardial hypoxia. The daily requirement for adults is 2–2.5 mg, for children from 6 months to 1 year — 0.5 mg, 1–1.5 years — 0.9 mg, 1.5–2 years — 1 mg, 3– 4 years old - 1.3 mg, 5-6 years old - 1.4 mg, 7-10 years old - 1.7 mg, 11-13 years old - 2 mg, for boys 14-17 years old - 2.2 mg, for girls 14-17 years - 1.9 mg.

Contraindications

Hypersensitivity.

Use during pregnancy and lactation

It is possible to use pyridoxine during pregnancy and lactation (breastfeeding) according to indications.

Special instructions

Use with caution in case of gastric and duodenal ulcer, ischemic heart disease.

In severe liver damage, high-dose pyridoxine can cause impaired function.

Composition

Active ingredient: pyridoxine hydrochloride - 50 mg

Excipients: water for injection.

Dosage and administration

Subcutaneously (s / c), intravenously (i / v), intramuscularly (i / m) if oral administration is not possible (with vomiting) and with malabsorption in the intestines. Adults - 50 - 100 mg / day in 1-2 doses, children - 20 mg. The course of treatment for adults is 1 month, for children - 2 weeks. With concomitant therapy with isoniazid, phthivazide - 5 to 10 mg / day.

For the treatment of sideroblastic anemia, it is prescribed orally, 100 mg daily or 100 mg IM, 2 times a week. It is advisable to take folic acid, cyanocobalamin, riboflavin at the same time.

In case of parkinsonism - i / m, 100 mg / day per course - 20-25 injections, the treatment course is repeated after 2-3 months or, starting with a dose of 50-100 mg / day, daily increase the dose by 50 mg, bringing it up to 300-400 mg / day, as a single injection for 12-15 days.

In depressions of involutional age - v / m, 200 mg / day.

For the treatment of pyridoxine-dependent convulsive syndrome in adults - in / in or in / m 30-600 mg for children - 10-100 mg daily.

Side effects

Allergic reactions, increased acidity of gastric juice.

Drug interaction

Isoniazid, cycloserine, penicillamine reduce the effect. Pharmaceutically incompatible with vitamins B1 and B12. It weakens the antiparkinsonian activity of levodopa.

Storage Conditions

In a light-proof location.

Expiration

3 years.

active substance

Pyridoxine

Prescription conditions from

pharmacies Prescription

lekarstvennaja form

Solution for

Possible product names

Pyridoxine ampoules 5%, 1 ml, 10 pcs.

PYRIDOXINE RR D / IN 50 MG / ML AMP. 1ML No. 10

Pyridoxine solution d / in 50mg / ml 1ml N10 amp

Pyridoxine solution d / in 50mg / ml 1ml N10 amp (PART 20pcs)

Pyridoxine solution for injection 5% 1 ml 10 pcs.

Borisov factory, Belarus



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