Serum against venom viper ordinary ampoule 150 AE syringe 1 pc. (antitoxin Jada viper ob knovennoy)

Release form

Injection.

Packing

1 pc

Indications

Treatment for people bitten by a viper.

Contraindications

Contraindication to continued use of serum is only the development of anaphylactic shock with the introduction of 0.1-0.25 ml of serum.

Use during pregnancy and lactation

During pregnancy, it is possible to use it for health reasons, taking into account the benefits to the mother and the possible risk to the fetus.

Lactation is not a contraindication.

Composition

1 dose contains:

Active substances: specific immunoglobulins of the protein fraction of the blood serum of horses hyperimmunized with venom of the viper ordinary 150 AE.

Dosage and Administration

Serum is administered subcutaneously, intramuscularly or intravenously as soon as possible after a snake bite.

First aid for a bitten on-site

An injured person is placed in the shade and given a plentiful drink: tea, coffee, milk, broth, water (drinking alcohol is prohibited) and 1 therapeutic dose of serum is administered regardless of the body weight of the bitten. In order to avoid anaphylactic shock or other allergic complications, before the introduction of serum, the patient is given 1-2 tablets of any antihistamine drug (diphenhydramine, pipolfen, tavegil, etc.) inside. The serum is injected subcutaneously fractionally (according to Bezredka) into any part of the victim’s body: first, 0.1 ml, in the absence of reaction after 10-15 minutes, 0.25 ml is administered, and then after 15 minutes in the absence of adverse reactions, the remaining serum. The opened ampoule should be covered with a sterile bandage or cotton swab.

After first aid, it is necessary to provide emergency hospitalization of the victim to the nearest medical facility, where treatment will continue. The patient is transported in a supine position. The bitten leg is bandaged to a healthy one, giving a slightly elevated position. When bitten in the arm, it is fixed in a bent position with a tissue thrown over the neck.

Assistance in a medical facility

The total administered dose of serum is determined by the doctor depending on the degree of intoxication: with a mild degree, intramuscularly 1-2 doses, with severe 4-5 doses, taking into account the dose administered before hospitalization.

In case of especially severe intoxication, serum is recommended to be administered intravenously slowly dropwise after dilution (1 / 5-1 / 10) with a sterile, 0.9% sodium chloride solution for injection heated to a temperature of (37 ± 1) ° С. Speed ​​of administration: at first 1 ml for 5 minutes, then 1 ml per minute. In exceptional cases, when it is impossible to carry out a drip infusion, a slow jet administration of a therapeutic dose of serum without dilution with a syringe is allowed. In order to avoid possible allergic reactions, 60-90 mg of prednisolone is injected into the patient jet before the start of intravenous infusion of serum. Intravenous administration of serum is allowed only to medical personnel!

Children use the same dosing principle as adults, regardless of weight and age.

In some cases, when a bite is contaminated with soil, wounds, tissue necrosis of any type, emergency tetanus prophylaxis is necessary in accordance with the profile instructionsactics of tetanus.

Side effects of

The administration of serum against viper venom can be accompanied by the development of various allergic reactions: immediate, occurring immediately after administration or several hours later and manifesting symptoms of anaphylactic shock, early - on the 2nd day after administration and distant - on 5-10 days . The latter are accompanied by a symptom complex of serum sickness (fever, the appearance of itching and rashes on the skin, joint pain, etc.). When an anaphylactic reaction occurs, the administration of serum is stopped. Adrenaline (epinephrine) (0.3-1 ml) is injected subcutaneously cordiamine (1.5-2 ml), prednisone 25 ml or hydrocortisone (50-100 ml), strophanthin (0.5 ml 0.04%) with glucose (20 ml 40% solution). Given the possibility of shock with the introduction of serum for each vaccine, it is necessary to ensure medical supervision within 1 hour after the end of the drug.

Serum administration should be registered in the established accounting forms with the obligatory indication of the date, method and time of administration, patient response, manufacturer and serial number of the drug.

Drug Interaction

Compatibility with other medicines containing foreign protein must be considered.

Overdose

Not established.

Storage conditions

Store and transport in accordance with the joint venture. 3.3.2.1248-03 at a temperature of 2 ° to 8 ° C.

Keep out of the reach of children.

Expiration

2 years.

Deystvuyuschee substances

antitoxin Jada viper ob knovennoy

Pharmacy

Prescription

dosage form

dosage form

injection solution



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