Sodium chloride (Sodium chloride)

Release form

infusion solution

Packing

Bottle 200 ml.

Pharmacological action

Sodium chloride - detoxification.

Pharmacodynamics

It has a detoxifying and rehydrating effect. Replenishes sodium deficiency in various pathological conditions. A 0.9% solution of sodium chloride is isotonic to human plasma and therefore is rapidly excreted from the vascular bed, only temporarily increasing the BCC (effectiveness with blood loss and shock is insufficient).

Pharmacokinetics

Sodium concentration - 142 mmol / L (plasma) and 145 mmol / L (interstitial fluid), chloride concentration - 101 mmol / l (interstitial fluid). It is excreted by the kidneys.

Indications

large loss of extracellular fluid or insufficient intake (toxic dyspepsia, cholera, diarrhea, "indomitable" vomiting, extensive burns with severe exudation, etc. a)

hypochloremia and hyponatremia with dehydration

intestinal obstruction

intoxication

washing the wounds, eyes, nasal mucosa, dissolving and diluting drugs and moisturizing dressings.

Contraindications

hypernatremia

acidosis

hyperchloremia

hypokalemia

extracellular hyperhydration

intracellular dehydration

pulmonary congestive pulmonary and cerebral pulmonary edema

Precautions: renal failure

heart failure

oligo- and anuria.

Special instructions

Caution is advised to use large volumes of sodium chloride in patients with impaired renal excretory function, with hypokalemia. The introduction of large quantities of the solution can lead to chloride acidosis, hyperhydration, increased excretion of potassium from the body.

Hypertonic solution is not used s / c and / m.

With prolonged use, it is necessary to control the concentration of electrolytes in plasma and daily diuresis.

The temperature of the infusion solution should be 38 ° C.

Ingredients

Active ingredients: sodium chloride 9 g

Excipients: water for injection - up to 1 l

Dosage and administration

Intravenous drip, externally.

Before administration, the solution is heated to 36–38 ° C. The dose is determined depending on the body's loss of fluid, Na + and Cl ?, and averages 1000 ml per day. With large losses of fluid and severe intoxication, up to 3000 ml per day can be administered. The speed of administration - 540 ml per hour, if necessary - the speed of administration is increased.

Children with dehydration, expressed in a decrease in blood pressure (without determining laboratory parameters) are administered 20-30 ml / kg. In the future, the dosage regimen is adjusted depending on laboratory parameters. With long-term administration of large doses of isotonic sodium chloride solution, it is necessary to control the content of electrolytes in plasma and urine.

Isotonic sodium chloride solution is used to wash wounds, eyes, nasal mucosa, moisturize dressings.

Side effects

Acidosis, hyperhydration, hypokalemia.

Storage conditions

In a dry, dark place at a temperature of no higher than 25 ° C.

Expiration

1 year.

Active ingredient

Sodium chloride

Terms of sale from

pharmacies prescription

dosage form

infusion solution



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