Sodium pikosulfat (Sodium pikosulfat)

Latin name

Slabilen

Packing

Bottle of 15 ml.

Pharmacological action

Pharmacodynamics

Sodium picosulfate is a laxative. Under the influence of intestinal microorganisms it is hydrolyzed to form an active form, which causes irritation of the receptors of the mucous membrane of the large intestine and increased peristalsis. The action occurs 10-12 hours after administration.

Pharmacokinetics of

After oral administration, it is not absorbed from the gastrointestinal tract and does not undergo hepatic-intestinal circulation.

Indications

Constipation due to hypotension and flaccid peristalsis of the colon. Regulation of stool with hemorrhoids, proctitis, anus cracks.

Preparation for surgical operations, instrumental and radiological examinations.

Contraindications

Hypersensitivity, intestinal obstruction, restrained hernia, acute inflammatory diseases of the abdominal organs, peritonitis, abdominal pain (of unclear origin), bleeding from the gastrointestinal tract, metrorrhagia, cystitis, severe dehydration 4 years old, dehydration ), pregnancy (I trimester).

Precautions - II and III trimesters of pregnancy, lactation.

Pregnancy and lactation

There are no reliable and well-controlled studies in pregnant women. Long-term experience of use did not reveal a negative effect of sodium picosulfate on pregnancy.

The use of sodium picosulfate in the first trimester of pregnancy is contraindicated. In the II and III trimesters of pregnancy (as with other laxatives), the use of the drug is possible only as directed by the doctor.

The active metabolite and its glucuronides are not excreted in breast milk. Thus, the drug can be used during breastfeeding.

Composition of

1 ml drops for oral administration contains:

Active ingredient:

sodium picosulfate 7.5 mg

Excipients:

methyl paraben sodium,

sorbitol hydrochloric acid solution 1 M,

purified water.

Dosage and administration

Inside with a little water, before bedtime. Adults, the initial dose of 10-20 drops, with persistent constipation - up to 30 drops. For children over 4 years of age, the initial dose is 5-8 drops.

Depending on the effect obtained, the dose is increased or decreased in subsequent doses. The maximum daily dose for adults is 30 drops for children - 15 drops.

Side effects

Diarrhea, abdominal pain, dehydration, water-electrolyte imbalance, weakness, cramps, decreased blood pressure.

Overdose

Symptoms: diarrhea, dehydration, lowering blood pressure, impaired electrolyte balance, convulsions. In addition, chronic overdose may develop ischemia of the mucous membrane of the colon, secondary hyperaldosteronism, urolithiasis, renal tubular lesions.

Treatment: gastric lavage, correction of water-electrolyte balance disorders, antispasmodics.

Storage conditions

In a dark place at a temperature not lower than 8 C.

Keep out of the reach of children.

Expiration

3 years.

Deystvuyuschee substances

Sodium pikosulfat

Terms

pharmacy leave without a prescription

Dosage form

Dosage form

oral drops



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