Sparex capsules prolong. action 200 mg 60 pcs. (Mebeverin)

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Pharmacological action

Antispasmodic myotropic action, It has a direct effect on the smooth muscles of the gastrointestinal tract (mainly the large intestine). Eliminates spasm without affecting normal intestinal motility. Inhibits phosphodiesterase. It stabilizes the level of cyclic adenosine monodiphosphoric acid. It does not have an anticholinergic effect.

Pharmacokinetics

When administered orally, it undergoes presystem hydrolysis and is not detected in plasma. It is metabolized in the liver to veratric acid and mebeverine alcohol. It is excreted mainly by the kidneys in the form of metabolites, in small quantities by bile. Mebeverin capsules have the property of prolonged release. Even after repeated administration, no significant cumulation is observed. Buy Sparex capsules prolong. action 200 mg 60 pcs. (Mebeverin) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Pharmacological action

Antispasmodic myotropic action, It has a direct effect on the smooth muscles of the gastrointestinal tract (mainly the large intestine). Eliminates spasm without affecting normal intestinal motility. Inhibits phosphodiesterase. It stabilizes the level of cyclic adenosine monodiphosphoric acid. It does not have an anticholinergic effect.

Pharmacokinetics

When administered orally, it undergoes presystem hydrolysis and is not detected in plasma. It is metabolized in the liver to veratric acid and mebeverine alcohol. It is excreted mainly by the kidneys in the form of metabolites, in small quantities by bile. Mebeverin capsules have the property of prolonged release. Even after repeated administration, no significant cumulation is observed.

Indications

In adults:

spasm of the gastrointestinal tract (including that caused by an organic disease)

intestinal colic

biliary colic

irritable bowel syndrome.

In children over 12 years of age:

functional disorders of the gastrointestinal tract, accompanied by abdominal pain.

Contraindications

Hypersensitivity

porphyria

pregnancy

children under 12 years of age (due to insufficient data on efficacy and safety).

Precautions: use during lactation.

Composition

1 caps.

mebeverine hydrochloride 200 mg

Excipients: silicon dioxide colloidal (aerosil) - 5 mg, hypromellose (hydroxypropyl methylcellulose) - 38 mg, povidone K90 - 5 mg, magnesium stearate - 2 mg.

Composition of hard gelatin capsule: case: titanium dioxide - 1.378 mg, gelatin - 44.522 mg, quinoline yellow dye - 0.308 mg, sunset yellow dye - 0.003 mg cap: titanium dioxide - 0.893 mg, gelatin - 28.686 mg, quinoline yellow dye - 0.199 mg, dye sunny sunset yellow - 0. 002 mg.

Dosage and administration

Inside adults and children over 12 years old, 1 capsule (200 mg) 2 times / day 20 minutes before meals (morning and evening). Swallow whole with water.

Side effects

Dizziness, headache, diarrhea, constipation.

Allergic reactions: urticaria, Quincke's edema, facial edema and exanthema.

Overdose of

Symptoms: CNS arousal. The specific antidote is unknown. Gastric lavage and symptomatic therapy are recommended.

Storage conditions

The drug should be stored in a dry, dark place and out of the reach of children at a temperature not exceeding 25 ° C.

Do not use after expiration date.

Shelf life

2 years.

active substance

Mebeverin

Pharmacy terms

prescription

Appointment

Adults prescribed by a doctor

Indications

of meteorism, from spazmov ZHKT, dyskinesia zhelchev vodyashtih Putten



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