Spazgan tablets, 20 pcs. (metamizol sodium , Pithophenone, Phenpiverine bromide)

Release form

Tablets.

Packaging

In a package of 20 pieces.

Pharmacological action

Spazgan - a combined analgesic and antispasmodic, contains three active ingredients: metamizole sodium - an analgesic non-narcotic drug, pitofenone hydrochloride has papaverine-like action and fenpiverine bromide - M-anticholinergic action.

Has a fast onset, prolonged analgesic and antispasmodic effect.

Indications

Mild or moderate pain syndrome with spasms of smooth muscles of internal organs:

renal colic,

biliary colic,

algodismenorea,

intestinal colic

biliary duct dyskinesia due to bile duct dyskinesia.

Contraindications

hypersensitivity to pyrazolone derivatives (butadione, tribuzon), other components of the

preparation severe liver or kidney dysfunctions

genetic lack of glucose-6-phosphate dehydrogenase

tachyarrhythmia

angle-closure form of glaucoma

prostate hypertrophy with a tendency to urinary retention

gastrointestinal disease age under 5 years.

Use during pregnancy and lactation

Contraindicated in pregnancy (especially the first trimester and the last 6 weeks), as well as during lactation.

Dosage and administration

Inside: adults and adolescents over 15 years: 1-2 tablets 4 times a day, without chewing, and washed down with a small amount of liquid.

Children 12-14 years old: single dose -1 tablet, maximum daily dose - 6 tablets (1.5 tablets 4 times a day),

8-11 years old - 0.5 tablets, maximum daily dose - 4 tablets (1 tablet 4 times per day), 5-7 years - 0.5 tablets, the maximum daily dose - 2 tablets (0.5 tablets 4 times a day).

Side effects

allergic reactions (skin rash, itching, urticaria, Quincke's edema rarely - anaphylactic shock in very rare cases - malignant exudative erythema (Stevens-Johnson syndrome),

toxic epidermal necrolysis (Redkoell syndrome) long-term administration or administration of high doses)

agranulocytosis,

leukopenia,

thrombocytopenia,

impaired renal function: oliguria, anuria, proteinuria, interstitial nephritis,

bronchospasm,

decrease in gastritis srdlprd, srdlgrd, srd stitching urine in red.

Very rarely - anticholinergic effects (dry mouth, decreased sweating, paresis of accommodation, tachycardia, urinary retention).

Drug Interaction

Concomitant administration of Spazgana with other non-narcotic analgesics may lead to mutual enhancement of toxic effects.

Tricyclic antidepressants, contraceptives, allopurinol disrupt metabolic metabolism in the liver and increase its toxicity.

Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes attenuate the effect of metamizole. Co-administration with ciclosporin reduces the latter's level in the blood. Sedatives and tranquilizers enhance Spazgan's analgesic action.

Consult your doctor when using these and other medicines at the same time.

Overdose

The following symptoms can be observed with overdose: vomiting, dry mouth, change in sweating, impaired accommodation, decreased blood pressure, drowsiness, confusion, impaired liver and kidney function.

Treatment: gastric lavage, administration of activated charcoal, symptomatic therapy.

Storage conditions

In a dry, dark place at a temperature of no higher than 25 ° C.

Expiration

3 years.

Active ingredient

Metamizole sodium, Pithophenone, Fenpiverin bromide

Dispensing conditions from

pharmacies No prescription

dosage form

dosage form

tablets

Wockhardt, India



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