Tagista tablets 16 mg, 30 pcs. (Betagistin)

Release form

Pills

Packing

30 pcs.

Pharmacological action of

Betagistin acts mainly on the histamine H1 and H3 receptors of the inner ear and central vestibular nuclei. By direct agonistic action on the H1 receptors of the vessels of the inner ear, as well as indirectly through action on the NS receptors, it improves microcirculation and capillary permeability, normalizes the pressure of the endolymph in the labyrinth and cochlea. However, betahistine increases blood flow in the basilar artery.

It has a pronounced central effect, being an inhibitor of the NK receptors of the vestibular nerve nuclei. Normalizes the conductivity in neurons of the vestibular nuclei at the level of the brain stem.

The clinical manifestation of these properties is a decrease in the frequency and intensity of dizziness, a decrease in tinnitus, and an improvement in hearing if it is reduced.

Pharmacokinetics

Absorbed rapidly, binding to plasma proteins is low. The time to reach maximum plasma concentration is 3 hours. It is almost completely excreted by the kidneys as a metabolite (2-pyridylacetic acid) within 24 hours. Half-life is 3-4 hours.

Indications

Treatment and prevention of vestibular dizziness of various origins

Syndromes including dizziness and headache, tinnitus, progressive hearing loss, nausea and vomiting

Illness or Meniere's syndrome.

Contraindications

Hypersensitivity to any of the components of the drug

age up to 18 years (due to lack of data)

pregnancy and lactation (due to lack of data).

With caution

Peptic ulcer of the stomach or duodenum (including history), pheochromocytoma, bronchial asthma. These patients should be regularly observed during treatment.

Use during pregnancy and lactation

Due to lack of data, the drug is contraindicated during pregnancy and lactation.

Special instructions

Effect on ability to drive vehicles and work with mechanisms

Betagistin does not have a sedative effect and does not affect the ability to drive a car or engage in activities that require quick psychomotor reactions.

Composition

1 tablet contains

Active ingredient: betahistine dihydrochloride 8.0 mg 16.0 mg 24.0 mg

Excipients: microcrystalline cellulose - 54.75 / 109.5 / 164.25 mg, povidone (Collidone 25) - 9.0 / 18.0 / 27.0 mg potato starch - 20.0 / 40.0 / 60.0 mg, citric acid - 2.0 / 4.0 / 6.0 mg, colloidal silicon dioxide (Aerosil ), - 3.0 / 6.0 / 9.0 mg, talc - 2.8 / 5.6 / 8.4 mg, magnesium stearate - 0.45 / 0.9 / 1.35 mg.

Dosage and Administration

Inside, with meals.

Tablets 16 mg: 1 / 2-1 tablet 3 times a day.

Improvement is usually noted already at the beginning of therapy, a stable therapeutic effect occurs after two weeks of treatment and can increase over several months of treatment. The treatment is long. The duration of treatment is determined individually.

Side effects

Gastrointestinal upset. the appearance of hypersensitivity reactions from the skin (rash, itching, urticaria), Quincke's edema.

Drug Interactions

Cases of interaction or incompatibility with other drugs are unknown.

Overdose

Symptoms: nausea, vomiting, convulsions.

Treatment: gastric lavage, activated carbon intake, symptomatic therapy.

Storage Conditions

In a dry, dark place at a temperature not exceeding 25 ° C. Keep out of reach of children.

Expiration date

3 years

Deystvuyushtee substance

Betagistin

dosage form

tablets

Prescription

Prescription

Adults prescribed by a doctor



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