tetracycline tablets 100 mg, 20 pcs. (tetracycline)

Release form

Tablets.

Packaging

20 pcs.

Pharmacological action of

Tetracycline has a bacteriostatic effect by inhibiting the synthesis of protein pathogens. Active against aerobic gram-positive bacteria: Staphylococcus spp. (including penicillinase producing strains), Streptococcus spp. Gram-negative bacteria: Neisseria gonorrhoeae, Bordetella pertussis, Enterobacter spp., Escherichia coli, Klebsiella spp., Salmonella spp., Shigella spp. anaerobic bacteria: Clostridium spp.

Indications

Infectious and inflammatory diseases caused by tetracycline-sensitive microorganisms, incl. pneumonia, bronchitis, pleural empyema, tonsillitis, cholecystitis, pyelonephritis, intestinal infections, endocarditis, endometritis, prostatitis, syphilis, gonorrhea, brucellosis, rickettsioses, purulent infections of soft tissues, trachoma osteomyelitis, conjunctivitis, acne blepharitis.

Prevention of postoperative infections.

Contraindications

Liver failure, leukopenia, mycoses, children under 8 years of age, pregnancy, lactation (breast-feeding), hypersensitivity to tetracycline.

Use during pregnancy and lactation

Tetracycline is contraindicated in pregnancy and lactation. Penetrates through the placental barrier. May cause long-term discoloration of teeth, enamel hypoplasia, suppression of bone growth of the skeleton of the fetus. In addition, tetracycline can cause the development of fatty liver.

Dosage and administration of

Inside adults - 250-500 mg every 6 hours. Children over 8 years old - 25-50 mg / kg every 6 hours.

Topically apply several times a day, if necessary, apply a weak bandage.

Locally - 3-5 times /

The maximum daily dose for adults when taken orally is 4 g.

Side effects of the digestive system: nausea, vomiting, anorexia, abdominal pain, diarrhea, constipation, dry mouth, glossitis, discoloration of the tongue, esophagitis, transient increase in liver transaminases, alkaline phosphatase, bilirubin concentration, residual nitrogen.

From the side of the central nervous system: dizziness, headache.

From the hemopoietic system: neutropenia, thrombocytopenia, hemolytic anemia.

Allergic reactions: skin rash, itching, eosinophilia, Quincke's edema.

Dermatological reactions: photosensitivity.

Effects due to chemotherapeutic action: candidal stomatitis, candidal vulvovaginitis, intestinal dysbiosis.

Local reactions: pain at the injection site.

Other: vitamin B hypovitaminosis

Drug Interaction

Drugs containing metal ions (antacids, preparations containing iron, magnesium, calcium) form inactive chelates with tetracycline, so their simultaneous use should be avoided.

Combination with penicillins, cephalosporins, exerting bactericidal action and being antagonists of bacteriostatic antibiotics (including tetracycline).

The development of intracranial hypertension may occur with concomitant use of tetracycline with retinol.

When administered with cholestyramine or colestipol, tetracycline absorption is impaired.

Storage conditions

Store in a dark place at a temperature not exceeding 25 ° C.

Shelf life

2 years.

tablet dosage form of tablets



Indications

Indications

Pyelonephritis, Skin infections, Bronchitis, Urinary tract infections, Pneumonia, Vaginal infections



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