Thrombopol tablets 75 mg, 30 pcs. (Atsetylsalytsylovaya acid)

Latin name

Trombopol



packaging 30 pcs

Indications

Prevention of acute myocardial infarction in the presence of risk factors (eg, diabetes mellitus, hyperlipidemia, hypertension, obesity, smoking, advanced age) and myocardial infarction.

Unstable angina pectoris.

Stroke prophylaxis (including in patients with transient cerebrovascular accident).

Prevention of transient cerebrovascular accident.

Prevention of thromboembolism after surgery and invasive vascular interventions (e.g. coronary artery bypass grafting, endarterectomy of the carotid arteries, arteriovenous bypass surgery, carotid artery angioplasty).

Prevention of deep vein thrombosis and thromboembolism of the pulmonary artery and its branches (including during prolonged immobilization as a result of extensive surgery).

Contraindications

erosive and ulcerative lesions of the gastrointestinal tract in the exacerbation phase

gastrointestinal bleeding

hemorrhagic diathesis

bronchial asthma induced by salicylates and NSAIDs srdlkosylochylocephalic acid and bronchial arrhythmias dose of 15 mg per week or more

I and III trimesters of pregnancy

lactation (breastfeeding)

age under 18

increased sensitivity sensitivity to the components of the drug Thrombopol

hypersensitivity to other NSAIDs.

Caution: the drug should be used for gout, hyperuricemia, gastric and duodenal ulcer or gastrointestinal bleeding (history), renal / hepatic insufficiency, bronchial asthma, chronic respiratory diseases, hay fever, nasal polyposis, drug allergy, while taking metrex at a dose of less than 15 mg / week., concomitant therapy with anticoagulants, in the second trimester of pregnancy.

Use during pregnancy and lactation

The use of the drug Trombopol in the I and III trimesters of pregnancy and during lactation is contraindicated. The use of salicylates in the first trimester of pregnancy leads to the development of cleavage of the upper palate, heart defects in the third trimester cause inhibition of labor, premature closure of the ductus arteriosus in the fetus, increased bleeding in the mother and fetus, and administration immediately before delivery can cause intracranial hemorrhage, especially in premature babies children.

In the second trimester of pregnancy, salicylates can be prescribed only after a rigorous assessment of the expected benefits of the therapy to the mother and the potential risk to the fetus. Salicylates and their metabolites in small quantities are excreted in breast milk. A random intake of salicylates during lactation is not accompanied by the development of adverse reactions in the child and does not require cessation of breastfeeding. However, with prolonged use of the drug or the appointment of a high dose, breastfeeding should be stopped immediately.

Composition

1 tablet contains:

Active ingredient: acetylsalicylic acid 75 mg

Excipients: corn starch, microcrystalline cellulose, sodium carboxymethyl starch

Shell composition: hypromellose, Acrylic Is (tablet coating mixture): methacrylic acid copolymer type C, talc, titanium dioxide, triethyl citrate, crimson dye (Ponso 4R), silicon dioxide sodium colloid sodium lauryl sulfate.

Dosage and administration

The drug is intended for prolonged use. The duration of therapy is determined by the doctor. The tablets are taken orally, regardless of the meal, without chewing, with a little water.

For the prevention of acute myocardial infarction: 75 mg per day or 150 mg per day are prescribed.

In order to prevent the onset of acute myocardial infarction in the presence of risk factors: 75 mg per day or 150 mg per day are prescribed.

In order to prevent recurrent myocardial infarction, with unstable angina, to prevent stroke and transient cerebrovascular accident, to prevent thromboembolic complications after surgery or invasive research: 75 mg per day or 150 mg per day are prescribed.

For the prevention of deep vein thrombosis and thromboembolism of the pulmonary artery and its branches: 75 mg per day or 150 mg per day are prescribed.

Side effects of the digestive system: nausea, vomiting, heartburn, pain in the abdomen, diarrhea, ulcers of the mucous membrane of the stomach and duodenum, including perforated, gastrointestinal bleeding, increased activity of liver enzymes.

From the respiratory system: bronchospasm.

From the side of the central nervous system: dizziness, tinnitus.

From the hematopoietic system: increased bleeding rarely - anemia.

Allergic reactions: urticaria, Quincke's edema.

Overdose

Symptoms: first symptoms - nausea, vomiting, tinnitus and shortness of breath. Hearing loss, vision disorders, headaches, motor excitement, drowsiness, convulsions, hyperthermia are also possible. In severe intoxication may develop acid-base and water-electrolyte balance (metabolic acidosis and dehydration). The symptoms of mild and moderate intoxication develop after the use of acetylsalicylic acid at a dose of 150-300 mg / kg. Symptoms of severe overdose develop at a dose of 300-500 mg / kg. The potentially lethal dose of acetylsalicylic acid is over 500 mg / kg.

Treatment: induce vomiting and wash the stomach (to reduce the absorption of the drug). Such actions give effect within 3-4 h after administration of the drug, and in the case of administration in excessive dose - up to 10 h. To reduce the absorption of acetylsalicylic acid, it is necessary to take activated carbon in the form of an aqueous suspension (dose for adults - 50-100 g, for children - 30-60 g), it is necessary to carefully monitor the violation of the water-electrolyte balance and replenish it. In order to accelerate the excretion of acetylsalicylic acid by the kidneys and in the treatment of acidosis, sodium bicarbonate should be given. The pH must be maintained within 7.0-7.5. For very severe intoxication, hemodialysis or peritoneal dialysis should be performed. Due to the possibility of respiratory acidosis, it is forbidden to take drugs that depress the CNS, for example, barbiturates. Patients with respiratory distress should be provided with airway and oxygen access. If necessary, perform intratracheal intubation and ensure IVL. There is no specific antidote.

Storage conditions

Store in a dry, dark place at a temperature not exceeding 25 ° C.

Expiration

2 years.

Active ingredient

Acetylsalicylic acid OTA

Dosage form

Dosage form

tablets

Polarma, Poland



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