Triftazine tablets 5 mg, 50 pcs. (trifluoperazine)

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Latin name

Triphtazinum Buy Triftazine tablets 5 mg, 50 pcs. (trifluoperazine) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Latin name

Triphtazinum

release form

film-coated tablets



packaging 50 pcs

Indications for

schizophrenia and other mental illnesses that occur with delusions, hallucinations and psychomotor agitation

vomiting of central origin.

Special instructions

During treatment, regular monitoring of blood pressure, pulse and liver, kidney and blood function is necessary.

Do not allow alcohol during treatment!

During the treatment period, it is necessary to refrain from engaging in potentially hazardous activities that require an increased concentration of attention and speed of psychomotor reactions.

Composition of

In 1 film-coated tablet contains:

active substance: trifluoperazine hydrochloride 5 mg

excipients: refined sugar, potato starch, aerosil, calcium stearate, gelatin, basic magnesium carbonate, indivironolamine, titanium wax, carmin, titanium wax dioxide, talc.

Dosage and administration of

Triftazine is taken orally after a meal.

Doses are selected individually according to the severity of the condition, for dose titration, it is advisable to use dosage forms with the appropriate (lower) dosage. Upon reaching the maximum therapeutic effect, the dose is gradually reduced to a maintenance one. Usually, for the treatment of anxiety, adults are prescribed 1 mg 2 times a day. For patients with psychotic disorders start 2-5 mg 2 times a day. To obtain the optimal therapeutic effect, the dose is gradually increased to 15-20 mg / day, divided by 2-3 doses, the maximum daily dose is 40 mg.

To obtain the desired therapeutic effect and improve the patient's condition, usually 2-3 weeks are needed.

Children 6-12 years old, with psychotic disorders, are prescribed 1 mg 1-2 times a day, if necessary, this dose can be increased to 4 mg / day. Dose for children over 12 years old - 5-6 mg per day, divided into several techniques.

Adults with vomiting - 1-2 mg 2 times a day. For elderly patients, the initial dose should be reduced by 2 times.

Side effects of the

From the nervous system: drowsiness, dizziness, insomnia, phenomena of mental indifference (with prolonged use), delayed reactions to external irritations. The use of triftazine is often accompanied by extrapyramidal disorders (dyskinesias, akinetorigid phenomena, akathisia, hyperkinesis, tremors, autonomic disorders), in isolated cases, convulsions. Antiparkinsonian drugs, tropacin, are used as correctors. trihexyphenidyl (cyclodol) and others. Dyskinesias (paroxysmal cramps in the muscles of the neck, tongue, bottom of the mouth, oculogyric crises) are stopped by sodium caffeine benzoate (2 ml of a 20% solution subcutaneously) and atropine (1 ml of a 0.1% solution subcutaneously).

With prolonged use, the development of tardive dyskinesia, less commonly, malignant antipsychotic syndrome, is possible.

From the senses: paresis of accommodation, with prolonged use - retinopathy, clouding of the lens and cornea.

From the genitourinary system: urinary retention, decreased potency, frigidity, decreased libido, ejaculation disorders, priapism, oliguria.

From the endocrine system: hypo- or hyperglycemia, glucosuria, amenorrhea, hyperprolactinemia, dysmenorrhea, galactorrhea, swelling or pain in the mammary glands, gynecomastia, weight gain.

From the digestive system: dry mouth, decreased appetite, constipation, bulimia, nausea, vomiting, diarrhea, gastralgia, cholestatic jaundice.

On the part of the sensory organs: visual impairment - paresis of accommodation (at the beginning of treatment), retinopathy, clouding of the lens and cornea.

Laboratory indicators: thrombocytopenia, lympho- and leukopenia, increased blood coagulation, anemia, agranulocytosis (more often at 4-10 weeks of treatment), pancytopenia, eosinophilia - less often than other phenothiazines, false-positive pregnancy tests.

From the cardiovascular system: tachycardia, decreased blood pressure (including orthostatic hypotension) especially in elderly patients and people with alcoholism, heart rhythm disturbances, prolonged QT interval, decreased or inverted T wave. Allergic reactions: skin rash, urticaria, angioedema (less often than other phenothiazines).

Other: pigmentation of the skin and conjunctiva, discoloration of the sclera and cornea, decreased tolerance to high temperatures (up to the development of heat stroke), melanosis.

Local reactions: intramuscular administration may cause infiltrates, and if liquid forms get on the skin - contact dermatitis.

Drug interaction

With the simultaneous use of trimethoprim enhances the action of hypoglycemic agents - sulfonylureas.

With the combined use of Biseptolum with thiazide diuretics, the risk of thrombocytopenia and increased bleeding increases.

Co-trimoxazole enhances the anticoagulant effect of warfarin and the anticonvulsant activity of phenytoin.

When used together, rifampicin decreases the half-life of trimethoprim.

The combined use of Biseptolum and cyclosporine after kidney transplantation worsens the patient's condition. maprotilin or monoamine oxidase inhibitors (MAOs) - increased risk of developing antipsychotic malignant syndrome with anticonvulsants - possibly lowering the seizure threshold with drugs for treating hyperthyroidism - increasing the risk of agranulocytosis with other drugs causing extrapyramidal reactions - possibly increasing the frequency and severity of extrapyramidal disorders with hypritic srdlp - severe orthostatic hypotension with ephedrine is possible - vasoconstriction is weakened effect of ephedrine. In the treatment with triftazine, administration of epinephrine (adrenaline) should be avoided, as the effect of epinephrine can be distorted, which can lead to a drop in blood pressure. The antiparkinsonian effect of levodopa is reduced due to blocking of dopamine receptors. Triftazine can suppress the effects of amphetamines, clonidine, guanethidine. Triftazin enhances the anticholinergic effects of other drugs, while the antipsychotic effect of antipsychotics may decrease.

With the simultaneous use of triftazine with prochlorperazine, prolonged loss of consciousness may occur.

Combination with lithium preparations increases the risk of extrapyramidal complications. Triftazin may mask some manifestations of ototoxicity (tinnitus, dizziness), drugs that have an ototoxic effect (e.g. antibiotics). Other hepatotoxic drugs increase the risk of hepatotoxicity. Antacids containing Al3 + and Mg2 + reduce the absorption of triftazine.

overdose

Symptoms: areflexia or hyperreflexia, fuzzy visual perception, cardiotoxicity (arrhythmia, heart failure, decrease in blood pressure, shock, tachycardia, change in QRS complex, fibrillation, fibrillation convulsions, disorientation, drowsiness, stupor or coma mydriasis, dry mouth, hyperpyrexia or hypothermia, muscle rigidity, vomiting, pulmonary edema or respiratory depression.

Treatment - symptomatic: with arrhythmia - intravenous (in / in) phenytoin 9-11 mg / kg, with heart failure - cardiac glycosides, with marked decrease in blood pressure - intravenous injection of fluid or vasopressor agents, such as norepinephrine alpha- and beta-adrenomimetics, such as epinephrine, as a paradoxical decrease in blood pressure due to blockade of alpha-adrenergic receptors by trifluoperazine), in convulsions - diazepam (avoid the appointment of barbiturates, followed by stvie vozmozhnoy posleduyuscheho oppression CNS and respiratory), with parkynsonyzme - dyfenyltropyn, diphenhydramine. Monitoring of cardiovascular function for at least 5 days, CNS function, breathing, body temperature measurement, psychiatrist consultation. Dialysis is ineffective.

Storage conditions

In a dry, dark place, out of the reach of children.

Shelf life

3 years.

Deystvuyushtee substance

Trifluoperazine

Dosage form

tablets

Possible Product Names

TRIFTAZINE TAB. PO 5MG No. 50

TRIFTAZINE TABL.P.O. 5MG N50

Triftazine tablets 5 mg 50 pcs.

Triftazine tablets 5 mg, 50 pcs.

Dalkhimpharm, Russia



Triftazine tablets 5 mg, 50 pcs. (trifluoperazine) florida in pharmacy online. Cheap price, instruction, side effects, dosage. Triftazine tablets 5 mg, 50 pcs. - Sale. PayPal accept. Free shipping florida. Fast international shipping.

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