Trimectal MV tablets 35 mg, 120 pcs. (Trimetazidine)

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Release form

Film-modified release tablets. Buy Trimectal MV tablets 35 mg, 120 pcs. (Trimetazidine) in newyork free shipping. Fast international shipping USA, AU, EU, UK and others.
Release form

Film-modified release tablets.

Packing

120 pcs.

Pharmacological action

Trimektal MV - universal anti-ischemic drug. It has antianginal, antihypoxic effect.

Directly affecting cardiomyocytes and brain neurons, optimizes their metabolism and function. The cytoprotective effect is due to increased energy potential, activation of oxidative decarboxylation and rationalization of oxygen consumption (increased aerobic glycolysis and blockade of fatty acid oxidation).

Trimectal supports myocardial contractility, prevents a decrease in the intracellular content of ATP and phosphocreatinin

Under conditions of acidosis, it normalizes the functioning of membrane ion channels, prevents the accumulation of calcium and sodium in cardiomyocytes, normalizes the intracellular content of potassium ions

Reduces intracellular and myocardial fibrosis, and reduces myocardial fibrosis and myocardia.

Prevents the damaging effects of free radicals, preserves the integrity of cell membranes prevents the activation of neutrophils in the ischemic zone, increases the duration of the electric potential, reduces the yield of creatine phosphokinase from the cells and the severity of ischemic damage to the myocardium.

With angina pectoris it reduces the frequency of seizures (nitrate intake decreases), after 2 weeks of treatment, exercise tolerance increases, and blood pressure drops decrease.

Hearing and results of vestibular tests in patients improve, dizziness and tinnitus decrease.

With vascular pathology, the eye restores the functional activity of the retina.

Indications

Coronary heart disease: prevention of angina attacks (in combination therapy)

Cochleovestibular disorders of ischemic nature, such as dizziness, tinnitus, hearing impairment.

In ophthalmology: chorioretinal vascular disorders with ischemic components.

Contraindications

Hypersensitivity to any component of the

preparation Renal failure (creatinine clearance below 15 ml / min)

Severe hepatic impairment

Pregnancy breastfeeding

Age not established 18 years (safety and.

Special instructions

Do not use for relief of angina attacks.

The drug is not indicated for the initial course of therapy for unstable angina pectoris or myocardial infarction.

In the event of an attack of angina pectoris, treatment should be reviewed and adapted.

During treatment with patients with coronary heart disease, there is a significant decrease in the daily need for nitrates.

The use of the drug does not affect the ability to drive a car and perform work requiring a high speed of mental and physical reactions.

Composition

1 tablet contains trimetazidine dihydrochloride - 0.035 g

excipients:

collidone SR [polyvinyl acetate 80%, povidone 19%, sodium lauryl sulfate 0.8%, silicon dioxide 0.2%],

calcium hydrogen phosphate dihydrate,

silicon dioxide colloidal (aerosil),

magnesium stearate

film sheath: hydroxypropyl methylcellulose),

talc,

titanium dioxide,

macrogol 4000 (polyethylene oxide 4000 or polyethylene glycol 4000) or film coat Advantia Prime 390009ZA09-white (hypromellose, talc, titanium dioxide, macrogol 4000).

Dosage and Administration

Inside, with meals.

Trimektal take 1 tablet 2 times a day (morning and evening).

The course of treatment as recommended by a doctor.

Side effects

Allergic reactions: pruritus, urticaria

From the gastrointestinal tract: gastralgia, diarrhea, nausea, vomiting (rarely).

From the central nervous system: often - dizziness, headache, asthenia very rarely - extrapyramidal disorders (tremor, rigidity, akinesia), reversible after discontinuation of the drug.

From the side of the cardiovascular system: rarely - orthostatic hypotension, "flushing" of blood to the skin of the face.

Drug interaction

In clinical trials of trimetazidine, it was shown that it promotes an increase in the anti-ischemic activity of other antianginal drugs, and other interactions were not observed.

Overdose of

Currently, cases of overdose of the drug Trimektal MV have not been reported.

Storage conditions

In a dry, dark place at a temperature not exceeding 25 ° C.

Keep out of the reach and sight of children!

Active ingredient

Trimetazidine



pharmacy terms for prescription

Form of Treatment

tablets

Indications

Angina, Yshemycheskaya disease heart



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