urdox capsules 250 mg 50 pcs. (ursodeoxycholic acid)

Release form

Capsules.

Packing

50 pcs

Indications

Primary biliary cirrhosis with no signs of decompensation

dissolution of small and medium cholesterol stones with a functioning gall bladder

biliary reflux gastritis.

Contraindications

X-ray-positive (high calcium) gallstones

non-functioning gallbladder

acute inflammatory diseases: gall bladder, bile duct, intestines

liver cirrhosis in the stage of decompensation

expressed liver function, pregnancy period and: lactation

children's age

hypersensitivity to the components of the drug.

Use during pregnancy and lactation

Contraindicated in pregnancy and lactation.

Composition

1 capsule contains:

Active ingredient:

ursodeoxycholic acid 250 mg.

Excipients:

corn starch,

silicon dioxide colloidal anhydrous,

magnesium stearate.

Shell composition:

titanium dioxide,

methylhydroxybenzoate,

propylhydroxybenzoate,

acetic acid,

gelatin.

Dosage and Administration

Inside.

To dissolve cholesterol gallstones

The average daily dose is 250-500 mg (after or with meals), which is 1-2 capsules. The course of treatment is from 4-6 months to 12 months or more. The dose for maintenance therapy is 250 mg once a day.

For biliary reflux gastritis

250 mg once daily. The course of treatment is set by the doctor.

Symptomatic treatment of primary biliary cirrhosis

The daily dose depends on body weight and ranges from 2 to 6 capsules (approximately 10 to 15 mg of ursodeoxycholic acid per 1 kg of body weight).

Recommended use:

Body weight 34-50 kg: 2 capsules (daily dose) in the morning - 1 afternoon - - in the evening - 1.

Body weight 51-65 kg: 3 capsules (daily dose) in the morning - 1 afternoon - 1 evening - 1.

Body weight 66-85 kg: 4 capsules (daily dose) in the morning - 1 afternoon - 1 in the evening - 2.

Body weight 86-110 kg: 5 capsules (daily dose) in the morning - 1 afternoon - 2 in the evening - 2

Body weight over 110 kg: 6 capsules (daily dose) in the morning - 2 in the afternoon - 2 in the evening - 2.

Side effects

Back pain abdominal pain diarrhea (may be dose-dependent)

calcification of gallstones transient (increase) activity of hepatic transaminases

alopecia

constipation, dizziness, nausea, and nausea .

Drug Interaction

It is not recommended to use concurrently with drugs, reducing intestinal absorption of bile acids (eg, cholestyramine) and with drugs that increase biliary elimination of cholesterol (estrogens, hormonal contraceptives, some lipid-lowering agents).

Concomitant use with potentially hepatotoxic agents is not recommended.

Overdose

Symptoms: increased side effects.

Treatment: carrying out detoxification activities and the appointment of colestyramine (for the formation of chelate complexes with bile acids).

Storage conditions

Store in a dry, dark place at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Expiration

4 years.

Active ingredient TVO

ursodeoxycholic acid

dosage form

dosage form

capsules

pharm , Russia



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