VisOptic eye drops 0.05% 15 ml (Tetryzolyn)

Latin name

VisOptic

Release form

eye drops.

Packing

15 ml - polymer dropper bottle (1) - packs of cardboard.

Pharmacological action

alpha-adrenergic agonist. It has a vasoconstrictor and decongestant effect.

When applied topically reduces conjunctival edema, burning sensations, soreness of the mucous membrane of the eyes, lacrimation.

The vasoconstrictor effect develops within a few minutes and lasts 4-8 hours.

Pharmacokinetics

When applied topically, systemic absorption is low.

Indications

moderate eye irritation: itching, swelling and hyperemia of the conjunctiva, burning, lacrimation, injection of sclera due to chemical and physical factors (dust, cosmetics, swimming in chlorinated water, exposure to bright light or radiation from a computer monitor)

aller

Contraindications

glaucoma

endothelial-epithelial corneal dystrophy

acute cardiovascular failure

bacterial eye infection

foreign body of the eye

children's age up to 3 years

drug sensitivity.

Caution should be used in arterial hypertension, arrhythmias, aneurysms, hyperthyroidism, pheochromocytoma, diabetes mellitus, severe organic diseases of the heart and blood vessels (including coronary heart disease), as well as during treatment with MAO inhibitors and other drugs that increase blood pressure.

Use during pregnancy and lactation

Use of the drug during pregnancy and lactation (breastfeeding) is possible only if the intended benefit to the mother outweighs the risk to the fetus or baby.

Composition of

In 1 ml of eye drops contains:

Active ingredient

Tetrizoline hydrochloride 500 mcg.

Excipients

Boric acid, sodium tetraborate decahydrate, disodium edetate dihydrate, benzalkonium chloride, purified water.

Dosage and administration

Adults and children 3 years of age are instilled 1-2 drops 2-3 times / day in the lower conjunctival sac of the affected eye.

If there is no improvement within 48 hours, further use of the drug should be discontinued and a doctor should be consulted.

Side effects

Local reactions: increased intraocular pressure, burning sensation and reactive hyperemia of the eye rarely - dilated pupil.

Systemic reactions: increased blood pressure, hyperglycemia, impaired heart function, headache, nausea, drowsiness, weakness, tremor, dizziness, insomnia, tachycardia, allergic reactions.

Drug Interaction

Concurrent use with MAO inhibitors, tricyclic antidepressants, guanethidine can cause hypertension, tachycardia.

Co-administration with reserpine, insulin, propranolol, general anesthesia, atropine increases the risk of cardiovascular effects of tetrizolin.

Concomitant use with guanethidine may provoke mydriasis with temporary visual impairment.

overdose

The development of systemic symptoms of overdose is possible by accidental or deliberate ingestion or overdosage with topical administration.

Symptoms: pupil dilation, nausea, cyanosis, fever, convulsions, arrhythmias, hypertension, pulmonary edema, dyspnoea. Excessive systemic absorption of imidazole derivatives can lead to CNS depression, accompanied by drowsiness, hypothermia, bradycardia, collapse, apnea and coma.

The risk of overdose symptoms associated with the absorption of the drug is high in young children, especially when swallowed. Overdose in children can be manifested by CNS depression, accompanied by drowsiness, excessive sweating, expressed hypotension, up to shock.

Treatment: appoint activated charcoal, gastric lavage, oxygen inhalation, use of antipyretic and anticonvulsants. Phentolamine 5 mg per 0.9% sodium chloride solution is slowly administered intravenously or 100 mg orally to reduce blood pressure. The specific antidote is unknown.

Storage conditions

The drug should be stored out of the reach of children at a temperature of 15 ° to 25 ° C.

Expiration

5 years.

After opening the vial, the drops should be used for 4 weeks.

Active ingredient

tetrisolin

Dosage form

dosage form

eye drops

K.O.Romfarm Company S.RL., Romania



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